What to Know About Biopsy Sampling and Pathology in Vasculitis?

AbstractPurpose of ReviewTo summarize the histologic findings of vasculitis, and to give some practical considerations on biopsy samples.Recent FindingsThe larger use of imaging and the discoveries of serological markers in the diagnosis of vasculitis have increased the clinical recognition of these entities. Nevertheless, biopsy remains the gold standard for diagnosis in most cases. So far, biopsies are also useful to obtain information about prognosis and to guide a more specific treatment. In recent years, less invasive diagnostic approaches have become available, lowering the risks related to the procedure and permitting a definite diagnosis in most cases.SummaryHistological examination permits a definite diagnosis of vasculitis. However, the findings may be nonspecific if not evaluated in the proper clinical setting. The interaction between clinicians and pathologists is crucial to obtain a definite diagnosis.
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research