A molecular mechanism governing memory precision
Nature Medicine 24, 390 (2018). doi:10.1038/nm.4532 Authors: Josue Haubrich & Karim Nader A key molecular mechanism has been identified that dictates whether memory will maintain or lose its details over time and that is relevant in post-traumatic stress disorder and dementia. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Josue Haubrich Karim Nader Tags: News and Views Source Type: research

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
Nature Medicine 24, 526 (2018). doi:10.1038/nm0418-526c Author: Nimitha R Mathew, Francis Baumgartner, Lukas Braun, David O'Sullivan, Simone Thomas, Miguel Waterhouse, Tony A Müller, Kathrin Hanke, Sanaz Taromi, Petya Apostolova, Anna L Illert, Wolfgang Melchinger, Sandra Duquesne, Annette Schmitt-Graeff, Lena Osswald, Kai-Li Yan, Arnim Weber, Sonia Tugues, Sabine Spath, Dietmar Pfeifer, Marie Follo, Rainer Claus, Michael Lübbert, Christoph Rummelt, Hartmut Bertz, Ralph Wäsch, Johanna Haag, Andrea Schmidts, Michael Schultheiss, Dominik Bettinger, Robert Thimme, Evelyn Ullrich, Yakup Tanriver, Giang L...
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A M ü ller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Tags: Erratum Source Type: research

Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Nature Medicine 24, 526 (2018). doi:10.1038/nm0418-526b Author: Hamid Bolouri, Jason E Farrar, Timothy Triche, Rhonda E Ries, Emilia L Lim, Todd A Alonzo, Yussanne Ma, Richard Moore, Andrew J Mungall, Marco A Marra, Jinghui Zhang, Xiaotu Ma, Yu Liu, Yanling Liu, Jaime M Guidry Auvil, Tanja M Davidsen, Patee Gesuwan, Leandro C Hermida, Bodour Salhia, Stephen Capone, Giridharan Ramsingh, Christian Michel Zwaan, Sanne Noort, Stephen R Piccolo, E Anders Kolb, Alan S Gamis, Malcolm A Smith, Daniela S Gerhard & Soheil Meshinchi (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Hamid Bolouri Jason E Farrar Timothy Triche Rhonda E Ries Emilia L Lim Todd A Alonzo Yussanne Ma Richard Moore Andrew J Mungall Marco A Marra Jinghui Zhang Xiaotu Ma Yu Liu Yanling Liu Jaime M Guidry Auvil Tanja M Davidsen Patee Gesuwan Leandro C Hermida Tags: Erratum Source Type: research

Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Nature Medicine 24, 526 (2018). doi:10.1038/nm0418-526a Author: Miguel Crespo, Eduardo Vilar, Su-Yi Tsai, Kyle Chang, Sadaf Amin, Tara Srinivasan, Tuo Zhang, Nina H Pipalia, Huanhuan Joyce Chen, Mavee Witherspoon, Miriam Gordillo, Jenny Zhaoying Xiang, Frederick R Maxfield, Steven Lipkin, Todd Evans & Shuibing Chen (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Miguel Crespo Eduardo Vilar Su-Yi Tsai Kyle Chang Sadaf Amin Tara Srinivasan Tuo Zhang Nina H Pipalia Huanhuan Joyce Chen Mavee Witherspoon Miriam Gordillo Jenny Zhaoying Xiang Frederick R Maxfield Steven Lipkin Todd Evans Shuibing Chen Tags: Corrigendum Source Type: research

Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness
Nature Medicine 24, 525 (2018). doi:10.1038/nm0418-525e Author: Nicholas M Morton, Jasmina Beltram, Roderick N Carter, Zoi Michailidou, Gregor Gorjanc, Clare McFadden, Martin E Barrios-Llerena, Sergio Rodriguez-Cuenca, Matthew T G Gibbins, Rhona E Aird, José Maria Moreno-Navarrete, Steven C Munger, Karen L Svenson, Annalisa Gastaldello, Lynne Ramage, Gregorio Naredo, Maximilian Zeyda, Zhao V Wang, Alexander F Howie, Aila Saari, Petra Sipilä, Thomas M Stulnig, Vilmundur Gudnason, Christopher J Kenyon, Jonathan R Seckl, Brian R Walker, Scott P Webster, Donald R Dunbar, Gary A Churchill, Antonio Vidal-Puig, ...
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Nicholas M Morton Jasmina Beltram Roderick N Carter Zoi Michailidou Gregor Gorjanc Clare McFadden Martin E Barrios-Llerena Sergio Rodriguez-Cuenca Matthew T G Gibbins Rhona E Aird Jos é Maria Moreno-Navarrete Steven C Munger Karen L Svenson Annalisa Gas Tags: Corrigendum Source Type: research

Corrigendum: Sex-specific transcriptional signatures in human depression
Nature Medicine 24, 525 (2018). doi:10.1038/nm0418-525d Author: Benoit Labonté, Olivia Engmann, Immanuel Purushothaman, Caroline Menard, Junshi Wang, Chunfeng Tan, Joseph R Scarpa, Gregory Moy, Yong-Hwee E Loh, Michael Cahill, Zachary S Lorsch, Peter J Hamilton, Erin S Calipari, Georgia E Hodes, Orna Issler, Hope Kronman, Madeline Pfau, Aleksandar L J Obradovic, Yan Dong, Rachael L Neve, Scott Russo, Andrew Kasarskis, Carol Tamminga, Naguib Mechawar, Gustavo Turecki, Bin Zhang, Li Shen & Eric J Nestler (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Benoit Labont é Olivia Engmann Immanuel Purushothaman Caroline Menard Junshi Wang Chunfeng Tan Joseph R Scarpa Gregory Moy Yong-Hwee E Loh Michael Cahill Zachary S Lorsch Peter J Hamilton Erin S Calipari Georgia E Hodes Orna Issler Hope Kronman Madeline Tags: Corrigendum Source Type: research

Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
Nature Medicine 24, 525 (2018). doi:10.1038/nm0418-525c Author: James J Morrow, Ian Bayles, Alister P W Funnell, Tyler E Miller, Alina Saiakhova, Michael M Lizardo, Cynthia F Bartels, Maaike Y Kapteijn, Stevephen Hung, Arnulfo Mendoza, Gursimran Dhillon, Daniel R Chee, Jay T Myers, Frederick Allen, Marco Gambarotti, Alberto Righi, Analisa DiFeo, Brian P Rubin, Alex Y Huang, Paul S Meltzer, Lee J Helman, Piero Picci, Henri H Versteeg, John A Stamatoyannopoulos, Chand Khanna & Peter C Scacheri (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: James J Morrow Ian Bayles Alister P W Funnell Tyler E Miller Alina Saiakhova Michael M Lizardo Cynthia F Bartels Maaike Y Kapteijn Stevephen Hung Arnulfo Mendoza Gursimran Dhillon Daniel R Chee Jay T Myers Frederick Allen Marco Gambarotti Alberto Righi An Tags: Corrigendum Source Type: research

Corrigendum: Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury
Nature Medicine 24, 525 (2018). doi:10.1038/nm0418-525b Author: Enrico Velardi, Jennifer J Tsai, Stefan Radtke, Kirsten Cooper, Kimon V Argyropoulos, Shieh Jae-Hung, Lauren F Young, Amina Lazrak, Odette M Smith, Sophie Lieberman, Fabiana Kreines, Yusuke Shono, Tobias Wertheimer, Robert R Jenq, Alan M Hanash, Prema Narayan, Zhenmin Lei, Malcolm A Moore, Hans-Peter Kiem, Marcel R M van den Brink & Jarrod A Dudakov (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Enrico Velardi Jennifer J Tsai Stefan Radtke Kirsten Cooper Kimon V Argyropoulos Shieh Jae-Hung Lauren F Young Amina Lazrak Odette M Smith Sophie Lieberman Fabiana Kreines Yusuke Shono Tobias Wertheimer Robert R Jenq Alan M Hanash Prema Narayan Zhenmin Le Tags: Corrigendum Source Type: research

Corrigendum: Classification and characterization of microsatellite instability across 18 cancer types
Nature Medicine 24, 525 (2018). doi:10.1038/nm0418-525a Author: Ronald J Hause, Colin C Pritchard, Jay Shendure & Stephen J Salipante (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Ronald J Hause Colin C Pritchard Jay Shendure Stephen J Salipante Tags: Corrigendum Source Type: research

Current understanding of the human microbiome
Nature Medicine 24, 392 (2018). doi:10.1038/nm.4517 Authors: Jack A Gilbert, Martin J Blaser, J Gregory Caporaso, Janet K Jansson, Susan V Lynch & Rob Knight (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Jack A Gilbert Martin J Blaser J Gregory Caporaso Janet K Jansson Susan V Lynch Rob Knight Tags: Review Source Type: research

Transplanted neural progenitors bridge gaps to benefit cord – injured monkeys
Nature Medicine 24, 388 (2018). doi:10.1038/nm.4531 Author: Steven A Goldman Human neural progenitor cells have been grafted successfully into rhesus monkeys with spinal cord hemisection, resulting in anatomic integration and improved neurological function. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Steven A Goldman Tags: News and Views Source Type: research

Catalyzing the field of precision oncology, one basket at a time
Nature Medicine 24, 387 (2018). doi:10.1038/nm.4530 Authors: William Pao & Imola Fodor A bedside strategy to overcome the limitations of testing in preclinical models and to determine the role of gene mutations and their targetability directly in patients is presented. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: William Pao Imola Fodor Tags: News and Views Source Type: research

Predicting leukemia relapse
Nature Medicine 24, 385 (2018). doi:10.1038/nm.4529 Author: José Ignacio Martín-Subero Mass cytometry of acute B cell lymphoblastic leukemias at diagnosis reveals intrapatient phenotypic heterogeneity and specific signatures that mimic cell developmental stage and predict future relapse. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Jos é Ignacio Mart í n-Subero Tags: News and Views Source Type: research

Inflammation weakens HIV prevention
Nature Medicine 24, 384 (2018). doi:10.1038/nm.4534 Author: Thomas J Hope The presence of multiple inflammatory cytokines predicts the failure of a topical 1% tenofovir microbicide gel to protect women against HIV infection. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Thomas J Hope Tags: News and Views Source Type: research

A new site of attack for a malaria vaccine
Nature Medicine 24, 382 (2018). doi:10.1038/nm.4533 Authors: Simon J Draper & Matthew K Higgins A newly discovered antibody epitope on the liver-infective form of the parasite that causes malaria opens new doors for vaccine development. (Source: Nature Medicine)
Source: Nature Medicine - April 10, 2018 Category: General Medicine Authors: Simon J Draper Matthew K Higgins Tags: News and Views Source Type: research