New Theory on How Insulin Resistance, Metabolic Disease Begin
Contact: Samiha KhannaPhone: 919-419-5069Email:samiha.khanna@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 4 p.m. (ET) on Monday, Sept. 26, 2016DURHAM, N.C. -- Does eating too much sugar cause type 2 diabetes?The answer may not be simple, but a study published Sept. 26 in the Journal of Clinical Investigation adds to growing research linking excessive sugar consumption -- specifically the sugar fructose -- to a rise in metabolic disease worldwide.The study, conducted in mice and corroborated in human liver samples, unveils a metabolic process that could upend previous ideas about how the body becomes resist...
Source: DukeHealth.org: Duke Health Features - September 28, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Duke Clinical Research Institute to Coordinate National Study of Childhood Health
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Wednesday, Sept. 21, 2016DURHAM, N.C. -- TheDuke Clinical Research Institute (DCRI) has been named the coordinating center as part of a $157-million federal initiative involved in studying how environmental factors affect childhood health.The grant from the National Institutes of Health (NIH) will fund the organizational framework of the Environmental Influences on Child Health Outcomes (ECHO) initiative. The DCRI has been awarded $14.7 million in fiscal year 2016. This award is a seven-year grant with a to...
Source: DukeHealth.org: Duke Health Features - September 22, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Duke Team Identifies Blood Biomarkers in Drug-Resistant Cancer Tumor Cells
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Wednesday, Sept. 21, 2016Duke Team Identifies Blood Biomarkers in Drug-Resistant Cancer Tumor Cells  DURHAM, N.C. -- While searching for  a non-invasive way to detect prostate cancer cells circulating in blood,Duke Cancer Instituteresearchers have identified some blood markers associated with tumor resistance to two common hormone therapies.In a study published online this month in the journalClinical Cancer Research, the Duke-led team reported that they isolated multiple key gene alterations in the circu...
Source: DukeHealth.org: Duke Health Features - September 21, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Humira Provides Effective, Non-Steroid Alternative for Eye Inflammation
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgHumira Provides Effective, Non-Steroid Alternative for Eye InflammationEMBARGOED FOR RELEASE until 5 p.m. (ET) on Wednesday, September 7, 2016DURHAM, N.C. -- Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn ’s disease, according to a study led by a Duke Health researcher.The Food& Drug Administration recently approved the additional use of adal...
Source: DukeHealth.org: Duke Health Features - September 8, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Cancer Centers Often Misinform Patients About Supportive Care Services
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Tuesday, Sept. 6, 2016DURHAM, N.C. – Using a “mystery shopper” approach, researchers atDuke Cancer Institute anonymously called most of the nation ’s comprehensive cancer centers to ask whether palliative care was available, and found barriers to accurate information nearly 40 percent of the time.Reporting their findings during the press program at the 2016 Palliative Care in Oncology Symposium, the researchers said front-line misinformation can impede access to supportive services that patients ove...
Source: DukeHealth.org: Duke Health Features - September 7, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Researchers Find Molecular Link Behind Aspirin’s Protective Powers
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Wednesday, Sept. 7, 2016Aspirin ’s ability to reduce the risk of both cardiovascular disease and colon cancer has been a welcome, yet puzzling, attribute of the pain reliever that has been a mainstay in medicine cabinets for more than 100 years. Now researchers atDuke Health have identified a new mechanism of aspirin ’s action that appears to explain the drug’s diverse benefits. Publishing in the journal EBioMedicine, the researchers describe how aspirin directly impacts the function of a gene regul...
Source: DukeHealth.org: Duke Health Features - September 7, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Immersion Pulmonary Edema May Cause Swimming Deaths During Triathlons
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Thursday, September 1, 2016DURHAM, N.C. --  Heart abnormalities linked to immersion pulmonary edema were present in a greater-than-expected proportion of triathletes who died during the competition’s swim portion, according to astudy led by researchers at Duke Health.The findings, published Aug. 29 in the journal BMJ Open Sport& Exercise Medicine, are based on an analysis of autopsy reports of people who died in the United States and Canada between 2008 and 2015 while participating in triathlons....
Source: DukeHealth.org: Duke Health Features - September 1, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Gastric Bypass is Better than Other Procedures for Sustainable Weight Loss
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 11 a.m. (ET) on Wednesday, August 31, 2016DURHAM, N.C. --  Gastric bypass surgery is more effective for weight loss and long-term weight maintenance than are other surgical procedures and non-surgical treatment, according to a study led by researchers at Duke Health and the Durham VA Medical Center.The study ’s findings, published Aug. 31 in the journal JAMA Surgery, are based on the analysis of ten years of medical records for veterans who underwent one of three different weight-loss surgery proc...
Source: DukeHealth.org: Duke Health Features - September 1, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Duke Health Receives Support from IBM to Advance Community Wellness Program
Contact: Sarah Avery Phone: 919-660-13064 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Thursday, Aug. 25, 2016Duke Health Receives Support from IBM to Advance Community Wellness ProgramDURHAM, N.C. --Duke Health was named among the first recipients of the IBM Health Corps award, and will be receiving expertise from some of IBM ’s top employees to build a communications infrastructure that will help connect members of Durham community health partnerships.Duke was one of five institutions worldwide selected as part of IBM ’s new Health Corps program, which aims to address disparities in he...
Source: DukeHealth.org: Duke Health Features - August 25, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Mouse Study Points Way to Shut Down Harmful Immune Response in Lupus
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Wednesday, Aug. 17, 2016DURHAM, N.C. – Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body’s ability to combat flu, according to Duke Health studies in mice.The molecules, called polymers, have commonly been used in gene-transfer experiments because they bind to the nucleic acid in DNA and RNA. When deployed directly in mice with lupus or an acute flu infection, the polymers home in on the DNA and RNA refuse from dying ...
Source: DukeHealth.org: Duke Health Features - August 18, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Probability Data Could Better Direct Lymph Node Removal for Thyroid Cancer
Contact: Samiha Khanna Phone: 919-419-5069 Email:samiha.khanna@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Tuesday, Aug. 16, 2016DURHAM, N.C. -- Surgeons operating on patients with advanced thyroid cancer are often conflicted when deciding how many lymph nodes they should remove to reduce the patient ’s risk of recurrence.If surgeons don ’t evaluate enough lymph nodes, they could leave cancer behind; but extensive surgery close to structures such as nerves, the voice box and parathyroid glands can carry serious risks.A new study from the Duke Clinical Research Institute and Duke Cancer Institute strives ...
Source: DukeHealth.org: Duke Health Features - August 16, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Paraplegics Regain Some Feeling, Movement After Using Brain-Machine Interfaces
This study was funded by grants from the Brazilian Financing Agency for Studies and Projects (FINEP 01 ·12·0514·00), Brazilian Ministry of Science, Technology and Innovation, and the Itaú Bank. The authors list additional acknowledgements in the manuscript. They declared no competing financial interests related to this work.### (Source: DukeHealth.org: Duke Health Features)
Source: DukeHealth.org: Duke Health Features - August 11, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Warfarin Use May Not Bring Long-Term Stability for Atrial Fibrillation
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 11 a.m. (ET) on Tuesday, Aug. 9, 2016DURHAM, N.C. -- Warfarin prescribed to prevent strokes in atrial fibrillation may not adequately control blood clotting over the long-term, even when patients have been historically stable on the drug, according to a study from the Duke Clinical Research Institute.The findings, published Aug. 9 in the Journal of the American Medical Association (JAMA), are based on an 18-month study of 3,749 patients diagnosed with atrial fibrillation, an irregular heart rhythm. T...
Source: DukeHealth.org: Duke Health Features - August 9, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Compound Shows Promise as Next-Generation Prostate Cancer Therapy
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 11 a.m. (ET) Monday, Aug. 8, 2016DURHAM, N.C. -- In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice.The potential foundation for a next-generation therapy, called tetraaryl cyclobutane, or CB, is being studied as an option for prostate tumors that have grown resistant to current anti-androgen drugs, notably enzalutamide.“Prostate cancer is the most p...
Source: DukeHealth.org: Duke Health Features - August 8, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Duke Team Identifies New ‘Mega-Complex’ Involved in Cell Signaling
Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 12 p.m. (noon, ET) on Thursday, Aug. 4, 2016DURHAM, N.C. -- Duke Health-led researchers have discovered new information about the signaling mechanism of cells that could one day help guide development of more specific drug therapies.For years, well-established science detailed the intricacies of how cells change function after receiving chemical signals from hormones, neurotransmitters or even drugs.  Receptors on the outside of cells were known to launch the signaling process, which alerts proteins tha...
Source: DukeHealth.org: Duke Health Features - August 4, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news