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Total 7072789 results found since Jan 2013.

Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics
Publication date: Available online 9 March 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Maristela L. Onozato, Clarence Yapp, Douglas Richardson, Tilak Sundaresan, Varun Chahal, Jesse Lee, James P. Sullivan, Marisa W. Madden, Hyo S. Shim, Mathew Liebers, Quan Ho, Shyamala Maheswaran, Daniel A. Haber, Zongli Zheng, Brian Clancy, Hunter L. Elliott, Jochen K. Lennerz, A. John IafrateThe quantification of changes in gene copy number is critical to our understanding of tumor biology and for the clinical management of cancer patients. DNA fluorescence in situ hybridization is the gold standard method to detect copy ...
Source: The Journal of Molecular Diagnostics - March 23, 2019 Category: Pathology Source Type: research

Arthroscopic Management of Osteoid Osteoma of the Ankle Joint: A Systematic Review of the Literature
Publication date: Available online 23 March 2019Source: The Journal of Foot and Ankle SurgeryAuthor(s): Susan M. Ge, Yousef Marwan, Abdullah Addar, Nizar Algarni, Ruth Chaytor, Robert E. TurcotteAbstractOsteoid osteomas (OOs) are rare benign bone tumors that may occur in various joints including the ankle. These tumors are generally removed via open surgical excision or radiofrequency ablation. However, when they occur intra-articularly, these treatments are more difficult to perform because of more difficult access and the increased risk of damaging articular cartilage. Therefore, some have advocated for the use of arthro...
Source: The Journal of Foot and Ankle Surgery - March 23, 2019 Category: Orthopaedics Source Type: research

Nonanimal Hyaluronic Acid for the Treatment of Ankle Osteoarthritis: AProspective, Single-Arm Cohort Study
This study shows promise for viscosupplementation with NASHA in the treatment of ankle OA. A single injection was associated with clinically meaningful reductions in pain and disability during a 26-week period and, in general, was well tolerated.
Source: The Journal of Foot and Ankle Surgery - March 23, 2019 Category: Orthopaedics Source Type: research

Noninvasive Interactive Neurostimulation Therapy for the Treatment of Low-Grade Lateral Ankle Sprain in the Professional Contact Sport Athlete Improves the Short-Term Recovery and Return to Sport: A Prospective, Randomized Controlled Trial
The objective of this prospective, double-blinded, randomized controlled trial was to compare the results in terms of improvement of a foot functional score, lower level of reported pain, and return to sports in 2 groups of contact sport athlete affected by a grade I or II lateral ankle sprain. Patients were randomized using random blocks to the NIN program (group I) or a sham device (group II). The outcome measurements were the use of a self-reported Inability Walking Scale, patient-reported subjective assessment of the level of pain using a standard visual analogue scale, and daily intake of nonsteroidal antiinflammatory...
Source: The Journal of Foot and Ankle Surgery - March 23, 2019 Category: Orthopaedics Source Type: research

Patrik Brundin: life on the river
Publication date: Available online 22 March 2019Source: The Lancet NeurologyAuthor(s): Adrian Burton
Source: The Lancet Neurology - March 23, 2019 Category: Neurology Source Type: research

Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders
Publication date: Available online 22 March 2019Source: The Lancet NeurologyAuthor(s): Daniel Friedman, Jacqueline A French, Mauro MaccarroneSummaryIn the past two decades, there has been an increasing interest in the therapeutic potential of cannabinoids for neurological disorders such as epilepsy, multiple sclerosis, pain, and neurodegenerative diseases. Cannabis-based treatments for pain and spasticity in patients with multiple sclerosis have been approved in some countries. Randomised controlled trials of plant-derived cannabidiol for treatment of Lennox-Gastaut syndrome and Dravet syndrome, two severe childhood-onset ...
Source: The Lancet Neurology - March 23, 2019 Category: Neurology Source Type: research

Closing the loop in India's sanitation campaign for public health gains
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): V R Raman, Arundati Muralidharan
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Department of Error
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s):
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Palestinian health care is a global responsibility
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Gene Feder, Anita Berlin, Saleem Haj-Yahia, Ann Louise Kinmonth, Paul Wallace
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Methods to overcome vaccine hesitancy
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Rajasekharan K Nayar, Anoop T Nair, Muhammed Shaffi, Kamala Swarnam, Anant Kumar, Minu Abraham, Jinbert Lordson, Chitra Grace
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

UN concerned about the right to health for migrants in Germany
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Kayvan Bozorgmehr, Anja Dieterich, Johanna Offe
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Action on salt in China – Authors' reply
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Feng J He, Graham A MacGregor
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Action on salt in China
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Luke N Allen
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Beyond representation: women at global health conferences
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Esther Schroeder, Connor Rochford, Maike Voss, Sabine Gabrysch
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

End government support for pro-alcohol research
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Saul J Newman
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Martin Eric Gore
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Geoff Watts
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Abortion as a moral good
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Katie Watson
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Anthony Fauci: fighting HIV/AIDS from the beginning
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Tony Kirby
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again, Eric Topol. Basic Books (2019), 400, US$42·00, ISBN: 9781541644632
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Indra Joshi
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Mali announces far-reaching health reform
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Paul Adepoju
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Second person reported in remission from HIV infection
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Tony Kirby
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Madagascar's battle for health
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Munyaradzi Makoni
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Offline: Public health and the fight against extremism
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Richard Horton
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Heroin body-packing and naloxone
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Maryam Vahabzadeh, Ali Banagozar Mohammadi
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

On the question of water: a matter of life and death
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): The Lancet
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

A tiered health-care delivery system for China
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): The Lancet
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Venezuelans' right to health crumbles amid political crisis
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): The Lancet
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Epithelial ovarian cancer
Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Stephanie Lheureux, Charlie Gourley, Ignace Vergote, Amit M OzaSummaryEpithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Treatment requires expert multidisciplinary care. Population-based screening has been ineffective, but new approaches for early diagnosis and prevention that leverage molecular genomics are in development. Initial therapy includes surgery and adjuvant therapy. Epithelial ovarian cancer is composed of distinct histological subtypes with uniqu...
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial
This study aimed at assessing whether lowering HVPG with β blockers could decrease the risk of decompensation or death in compensated cirrhosis with CSPH.MethodsThis study on β blockers to prevent decompensation of cirrhosis with portal hypertension (PREDESCI) was an investigator-initiated, double-blind, randomised controlled trial done in eight hospitals in Spain. We enrolled patients with compensated cirrhosis and CSPH without high-risk varices. All participants had HVPG measurements with assessment of acute HVPG-response to intravenous propranolol. Responders (HVPG-decrease ≥10%) were randomly assigned to propranolo...
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

When ethics and politics collide in donor-funded global health research
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Katerini T Storeng, Jennifer Palmer
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Three-dimensional visualisation of the fetal heart using prenatal MRI with motion-corrected slice-volume registration: a prospective, single-centre cohort study
The objective of this study was to investigate the combination of prenatal MRI with novel, motion-corrected 3D image registration software, as an adjunct to fetal echocardiography in the diagnosis of congenital heart disease.MethodsPregnant women carrying a fetus with known or suspected congenital heart disease were recruited via a tertiary fetal cardiology unit. After initial validation experiments to assess the general reliability of the approach, MRI data were acquired in 85 consecutive fetuses, as overlapping stacks of 2D images. These images were then processed with a bespoke open-source reconstruction algorithm to pr...
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Keeping promises to women, children, and adolescents
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Flavia Bustreo, Marleen Temmerman
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Fetal MRI and prenatal diagnosis of congenital heart defects
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Jimmy Espinoza
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Beyond birthweight: benefits and risks of preventing malaria in pregnancy
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Miriam K Laufer
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Prevention of decompensation in cirrhosis: a new youth for β blockers
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Sharon Levy, Didier Samuel
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

Monthly sulfadoxine–pyrimethamine versus dihydroartemisinin–piperaquine for intermittent preventive treatment of malaria in pregnancy: a double-blind, randomised, controlled, superiority trial
Publication date: Available online 22 March 2019Source: The LancetAuthor(s): Richard Kajubi, Teddy Ochieng, Abel Kakuru, Prasanna Jagannathan, Miriam Nakalembe, Theodore Ruel, Bishop Opira, Harriet Ochokoru, John Ategeka, Patience Nayebare, Tamara D Clark, Diane V Havlir, Moses R Kamya, Grant DorseySummaryBackgroundIntermittent treatment with sulfadoxine–pyrimethamine, recommended for prevention of malaria in pregnant women throughout sub-Saharan Africa, is threatened by parasite resistance. We assessed the efficacy and safety of intermittent preventive treatment with dihydroartemisinin–piperaquine as an alternative to...
Source: The Lancet - March 23, 2019 Category: General Medicine Source Type: research

The role of social cues in supporting students to overcome challenges in online multi-stage assignments
This study explores the challenges experienced by students while completing online multi-stage assignments and the processes of self-regulated learning students engaged with to overcome such challenges. We present interview data from three qualitative case studies involving 34 students across two Australian universities. The results show all students experienced challenges while working on multi-stage assignments. Students engaged with both online and offline social cues to regulate their learning and overcome task challenges. We discuss the design implications and provide recommendations for further research.
Source: The Internet and Higher Education - March 23, 2019 Category: Information Technology Source Type: research

Conditioning with busulfan plus melphalan versus melphalan alone before autologous haemopoietic cell transplantation for multiple myeloma: an open-label, randomised, phase 3 trial
This study was funded in part by the National Institutes of Health (NIH) through MD Anderson's Cancer Center Support Grant ( CA016672).
Source: The Lancet Haematology - March 23, 2019 Category: Hematology Source Type: research

Improving the conditioning regimen in multiple myeloma
Publication date: Available online 22 March 2019Source: The Lancet HaematologyAuthor(s): María-Victoria Mateos, Verónica González-Calle
Source: The Lancet Haematology - March 23, 2019 Category: Hematology Source Type: research

Effect of framework material on the color of implant-supported complete-arch fixed dental prostheses
ConclusionsFeldspathic porcelain layered for teeth and gingiva was lighter on Zir frameworks than on Ti frameworks. Porcelain on the facial aspects of teeth was redder and yellower on Ti compared with Zir. Gingival porcelain on Zir was yellower than that on Ti. The color of layering porcelain on the teeth and gingival areas was significantly different when different frameworks (Ti or Zir) were used.
Source: The Journal of Prosthetic Dentistry - March 23, 2019 Category: Dentistry Source Type: research

The tribulation of tracheal surgery
Publication date: Available online 22 March 2019Source: The Annals of Thoracic SurgeryAuthor(s): Simone T. Timman, Sailay Siddiqi, Ad F.T.M. Verhagen
Source: The Annals of Thoracic Surgery - March 23, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

The Devoted Grandma: Is a Social Indication for TAVR Acceptable?
Publication date: Available online 22 March 2019Source: The Annals of Thoracic SurgeryAuthor(s): Andrea J. Carpenter, William Novick, Robert M. Sade
Source: The Annals of Thoracic Surgery - March 23, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

A seismic quiescence before the 2017 Mw 7.3 Sarpol Zahab (Iran) earthquake: Detection and analysis by improved RTL method
Publication date: Available online 22 March 2019Source: Physics of the Earth and Planetary InteriorsAuthor(s): Stefania Gentili, Antonella Peresan, Mohammad Talebi, Mehdi Zare, Rita Di GiovambattistaAbstractA major earthquake, with magnitude Mw 7.3, struck Sarpol Zahab (Kermanshah province, Iran) on November 122,017, causing extended damage and casualties. The epicenter was located in the Northwestern part of the Zagros mountain range, an active belt originated by the Arabia-Eurasia collision.We explore seismicity preceding this earthquake, by using the Iranian Seismological Center instrumental earthquake catalog (IGTU), w...
Source: Physics of the Earth and Planetary Interiors - March 23, 2019 Category: Physics Source Type: research

Controversies, Consensus and Collaboration in the Use of I-131 Therapy in Differentiated Thyroid Cancer.
CONCLUSION: By fostering an open, productive, evidence-based discussion, the Martinique meeting restored trust, confidence and a sense of collegiality between individuals and organizations that are committed to optimal thyroid disease management. The result of this first meeting is a set of nine principles (The Martinique Principles) that 1) describe a commitment to proactive, purposeful and inclusive inter-disciplinary cooperation, 2) define the goals of radioiodine therapy as either remnant ablation, adjuvant treatment or treatment of known disease, 3) describe the importance of evaluating post-operative disease status a...
Source: Thyroid : official journal of the American Thyroid Association - March 23, 2019 Category: Endocrinology Tags: Thyroid Source Type: research

The Informed Thyroid: Address Your T3
It’s a peculiar, though not entirely unexpected phenomenon: You’d expect endocrinologists, specialists in glandular health, to be the champions of restoring optimal thyroid status. Instead, they are the most misinformed and neglectful. Much of this is due to their ignorance of the emerging science that has emerged over the past two decades on the impact of INDUSTRIAL CHEMICALS on thyroid status, something they would not be aware of unless they examine the TOXICOLOGICAL evidence demonstrating that the thyroid gland and thyroid hormones are disrupted by common chemical exposures. Ignore your ignorant endocrinolo...
Source: Wheat Belly Blog - March 23, 2019 Category: Cardiology Authors: Dr. Davis Tags: Hypothyroidism T3 thyroid hormone diy health free t3 undoctored wheat belly Source Type: blogs

Plant-Microbe Interactions in the Rhizosphere review
Excerpt from a book review of Plant-Microbe Interactions in the Rhizosphere"topical and well-referenced ... written by experts in their respective fields, providing an authoritative overview ... particularly useful to final-year graduate and postgraduate students, and to plant scientists and microbiologists ... valuable to soil scientists and ecologists" from Eur. J. Soil Sci. read more ...Plant-Microbe Interactions in the RhizosphereEdited by: Adam Schikora"recommended for anyone involved in plant science or environmental microbiology" (Biotechnol. Agron. Soc. Environ.) read more ...
Source: Microbiology Blog: The weblog for microbiologists. - March 23, 2019 Category: Microbiology Source Type: blogs

Physician keynotes at TexMed 2019 and the 2019 ASPR Annual Conference
Physician Speaking by KevinMD is the only physician-run, all-physician boutique speakers bureau in existence. We are practicing physicians who are as comfortable on stage as we are in the hospital, clinic, or operating room. We have the credibility to inspire your audience, and the authenticity to make a difference. We’re proud to be keynoting the […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - March 23, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/admin" rel="tag" > Admin < /a > < /span > Tags: Potpourri Source Type: blogs

Nanotechnology Will Break The Curse Running Through Generations
A fictional tale about the healing power of technology The mutation of the CDH1 gene determines the fate of generations of men in a Czech small town. The great-grandfather dies unexpectedly upon returning home from the trenches of the first World War – he survives the bullets of the Italian front but gives in after a pint of beer and schnitzel. The grandfather was already diagnosed with an illness, gastric cancer, which required the removal of his entire stomach – but his life couldn’t be saved either. His son was luckier, he was diagnosed in time with an early stage hereditary diffuse gastric cancer and had e...
Source: The Medical Futurist - March 23, 2019 Category: Information Technology Authors: nora Tags: Medical Science Fiction Nanotechnology in Medicine cancer generation genetic disorder genetics Innovation sci-fi Surgery Source Type: blogs

Papillomatosis of the hard palate.
Authors: Leon L, Shuen AY, Vizirakis M, McCord C PMID: 30898306 [PubMed - as supplied by publisher]
Source: Journal of the American Dental Association - March 23, 2019 Category: Dentistry Tags: J Am Dent Assoc Source Type: research