Playing the Long Game: Therapeutic Hypothermia’s Impact on Quality-of-Life After Pediatric Cardiac Arrest*

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Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Editorials Source Type: research

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Graves dating back thousands of years are giving up their secrets, as new ways to pin down the sex of old bones are overturning long-held, biased beliefs about gender and loveIn the early summer of 2009, a team of archaeologists arrived at a construction site in a residential neighbourhood of Modena, Italy. Digging had started for a new building and in the process workers unearthed a cemetery, dating back 1,500 years. There were 11 graves, but it quickly became clear that one of them was not like the others. Instead of a single skeleton, Tomb 16 contained two and they were holding hands.“Here’s the demonstratio...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Archaeology Anthropology Science Italy Gender Sexuality Evolution Source Type: news
An improved understanding of genetic etiological heterogeneity in a psychiatric condition may help us (a) isolate a neurophysiological ‘final common pathway’ by identifying its upstream genetic origins and (b) facilitate characterization of the condition’s phenotypic variation. This review aims to identify existing genetic heterogeneity measurements in the psychiatric literature and provides a conceptual review of their mechanisms, limitations, and assumptions. The Scopus database was searched for studies that quantified genetic heterogeneity or correlation of psychiatric phenotypes with human genetic dat...
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Review Source Type: research
In this study, we examined the effect of 5-HTTLPR polymorphism on prenatal and postnatal symptoms of depression and posttraumatic stress in women. Methods A longitudinal design with three points – time 1 (32–40 weeks gestation); time 2 (2 or 3 weeks after birth), and time 3 (3 months after birth) – was made. A total of 141 women were recruited during childbirth preparation courses. At time 1, women completed the Beck Depression Inventory (BDI) and the Los Angeles Symptoms Checklist (LASC). At time 2, they fulfilled BDI and Edinburgh Postnatal Depression Scale (EDPS), LASC and the Peri...
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Original Articles Source Type: research
Although resilience has been identified to be moderately heritable, little is known about the genetic variants involved. While there has not yet been a robust genome-wide association study (GWAS) of resilience, existing GWAS of related phenotypes may provide a starting point for developing our understanding of the heritability of resilience. In a sample of older, US adults (N = 9480), we examined the extent to which proxy polygenic scores (PGS) explained the variance in resilience. Four of the 32 PGS assessed (subjective wellbeing, neuroticism, depressive symptoms and educational attainment) reached significa...
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Original Articles Source Type: research
Conclusion Our findings suggest the potential of measuring the transcript levels of hsa-let7d-5p and hsa-let7g-5p miRNAs as a diagnostic biomarker for AD.
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Original Articles Source Type: research
Conclusion Although 17q12 deletion syndrome has been associated with bipolar disorder, very few such cases have been described in the literature. Genetic counseling should be considered in patients with remarkable phenotype, complex symptomatology, neurodevelopmental disorder and additional conspicuous medical conditions.
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Brief Report Source Type: research
We analyze the leukocyte telomere length (LTL) and telomerase activity in patients with major depressive disorder (MDD) before and after treatment with selective serotonin reuptake inhibitors (SSRIs). Before treatment, there was a reduction in the LTLs and expression levels of the human telomerase reverse transcriptase (hTERT) in the patients with MDD compared with controls. However, after 24 weeks of treatment with SSRIs, there was a significant increase in the LTLs and the expression levels of hTERT, with values approaching those observed in the controls. We conclude that SSRI antidepressant therapy can directly influenc...
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Brief Report Source Type: research
Can anyone help clarify if your residency is a 501c3 hospital, those IBR payments made towards your loans count towards the 10-year PSLF eligibility? Any super non-trad students in similar shoes where they were paying off their student loans with their premed job, continued paying it off during residency, and became debt-free with PSLF during residency? I just learned about PSLF. I have to do retro-active PSLF application and employment certification, but am just trying to figure out if I... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical (MD) Source Type: forums
This is now the BoWWling sign ups thread. Disregard all things that were here before. Cycle timing will be 36/12 or hybrid. Start date is maybe Wednesday the 19th. Direct all questions to @cubsrule4e! @Melchizedek and crew will be running Assassination Classroom next to fulfil your basics WW needs.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Veterinary Source Type: forums
Hello, I have completed my undergraduate degree with a 3.7 GPA and am currently applying to medical schools (MDs). However, I haven't had much success this cycle and am planning for becoming a reapplicant with an improved app. However, I am currently doing a Master's degree, but my grades so far (halfway into the one-year program) are low at ~3.4 GPA. (This is a regular Master's degree and not a SMP for clarification.) I am considering withdrawing from my Master's degree if the lower grades... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical (MD) Source Type: forums
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