Binge-drinking among millennials linked to skyrocketing rates of liver disease

(Natural News) The liver is one of the most resilient organs in your body, due to its unique ability to regenerate new and healthy tissue to replace damaged ones. This is important because the liver plays a major role in the body’s metabolic functions like breaking down substances and eliminating toxins from the body. Also, it even helps...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Abstract The close connection and interaction between the cardiac and the liver functions are well-known, as cirrhotic cardiomyopathy is an important clinical entity which best describes the mutual pathogenical influence between these two organs. Due to the fact that cardiac dysfunction in patients with chronic hepatic disorders is oligosymptomatic or even asymptomatic, an early diagnosis represents a challenge for every physician. Syndecan-1-a transmembrane proteoglycan that exerts its functions mainly via its heparane sulfate chains-is a very promising biomarker, correlated not only with the degree of cardiac fi...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
Publication date: Available online 10 December 2019Source: Acta Pharmaceutica Sinica BAuthor(s): Tingting Yan, Nana Yan, Ping Wang, Yangliu Xia, Haiping Hao, Guangji Wang, Frank J. GonzalezAbstractFew medications are available for meeting the increasing disease burden of nonalcoholic fatty liver disease (NAFLD) and its progressive stage, nonalcoholic steatohepatitis (NASH). Traditional herb medicines (THM) have been used for centuries to treat indigenous people with various symptoms but without clarified modern-defined disease type and mechanisms. In modern times, NAFLD was defined as a common chronic disease leading to mo...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Contributors : Jay K Kolls ; Timothy W Hand ; Kong ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIL-17 and IL-17R signaling in the intestinal epithelium regulate the intestinal microbiome. Given the reported links between intestinal dysbiosis, bacterial translocation, and liver disease, we hypothesized that intestinal IL-17R signaling plays a critical role in mitigating hepatic inflammation. To test this, we studied intestinal epithelial-specific IL-17RA deficient mice in a model of concanavalin A hepatitis. Absence of enteric IL-17RA signaling exacerbated hepatitis and hepatocy...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia (XMEN) disease is caused by deficiency of the magnesium transporter 1 (MAGT1) gene. We studied 23 patients with XMEN, 8 of whom were EBV naive. We observed lymphadenopathy (LAD), cytopenias, liver disease, cavum septum pellucidum (CSP), and increased CD4–CD8–B220–TCRαβ+ T cells (αβDNTs), in addition to the previously described features of an inverted CD4/CD8 ratio, CD4+ T lymphocytopenia, increased B cells, dysgammaglobulinemia, and decreased expression of the natural killer group 2, member D (NKG2D) recept...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Coeliac disease is a chronic and systemic autoimmune condition triggered by gluten ingestion in genetically predisposed subjects. Currently, the only effective treatment available is a strict, lifelong gluten-free diet. However, patients perceive gluten withdrawal as an unsustainable burden in their life and some of them can exhibit persistent symptoms despite a strict diet. Thus, gluten-free diet represents a challenge, leading scientists to look for alternative or complementary treatments. This review will focus on non-dietary therapies for coeliac disease highlighting six therapeutic strategies: (1) decreasing gluten im...
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Review Article Source Type: research
There is evidence of an increased fragility in the inflamed esophagus of patients with eosinophilic esophagitis (EoE). We performed a systematic review on presentation, management and outcomes of and surgical interventions for esophageal perforation in these patients, by searching in the MEDLINE, Embase and Scopus databases.Of the 599 references identified, 41 full-papers and 9 abstract met the inclusion criteria. Overall, 76 esophageal perforation episodes in 70 individual patients aged between 9 and 65 years were reported.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Alimentary Tract Source Type: research
Condition:   Fatty Liver Disease Intervention:   Other: A complete cardiovascular and liver characterization will be carried out Sponsors:   Instituto de Investigación Marqués de Valdecilla;   Hospital Universitario Puerta del Hierro Majadahonda.;   Hospital Universitario Ramón y Cajal;   Hospital General Universitario Gregorio Marañón Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Non-Alcoholic Fatty Liver Disease;   Non-alcoholic Fatty Liver;   Non-alcoholic Steatohepatitis Intervention:   Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   The European Association for the Study of the Liver;   Children's Liver Disease Foundation Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Fatty Liver Disease Intervention:   Other: A complete cardiovascular and liver characterization will be carried out Sponsors:   Instituto de Investigación Marqués de Valdecilla;   Hospital Universitario Puerta del Hierro Majadahonda.;   Hospital Universitario Ramón y Cajal;   Hospital General Universitario Gregorio Marañón Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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