Lychee fruit found to be a natural remedy for gastric ulcers

(Natural News) Lychees (Litchi chinensis) are a tropical fruit with a sweet and flowery flavor. It contains antioxidants, minerals, and vitamins. However, according to one study, the fruit can also potentially prevent and treat gastroesophageal inflammatory diseases like acute reflux esophagitis (RE) and gastric ulcer (GU). The study, published in the Journal of Medicinal Food, utilized animal models to see...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Publication date: Available online 1 March 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Arun Kumar Awasthi, Lalit Kumar, Punit Tripathi, Madhava Golla, Cirandur Suresh Reddy, Pramod KumarAbstractPantoprazole sodium, a substituted benzimidazole derivative, is an irreversible proton pump inhibitor which is primarily used for the treatment of duodenal ulcers, gastric ulcers, and gastroesophageal reflux disease (GERD). The monographs of European Pharmacopoeia (Ph. Eur.) and United States Pharmacopoeia (USP) specify six impurities, viz.; impurities A, B, C, D, E and F, respectively for its active pharmaceutical ingr...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 1 March 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Arun Kumar Awasthi, Lalit Kumar, Punit Tripathi, Madhava Golla, Cirandur Suresh Reddy, Pramod KumarAbstractPantoprazole sodium, a substituted benzimidazole derivative, is an irreversible proton pump inhibitor which is primarily used for the treatment of duodenal ulcers, gastric ulcers, and gastroesophageal reflux disease (GERD). The monographs of European Pharmacopoeia (Ph. Eur.) and United States Pharmacopeia (USP) specified six impurities, viz.; impurities A, B, C, D, E and F, respectively for this active pharmaceutical in...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Abstract INTRODUCTION: The introduction of proton pump inhibitors (PPIs) into clinical practice has greatly improved our therapeutic approach to acid-related diseases for their efficacy and safety. Areas Covered:The following evidence-based indications for PPI use are acknowledged by many scientific societies: treatment of the various forms and complications of gastroesophageal reflux disease, eradication of H. pylori infection in combination with two or more antibiotics, short- and long-term therapy of H. pylori-negative peptic ulcers, healing and prevention of NSAID/COXIB-associated gastric ulcers, co-therapy wi...
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Tags: Expert Rev Clin Pharmacol Source Type: research
Abstract Endogenous prostaglandins (PGs), produced from arachidonic acid by the two isoforms of cyclooxygenase (COX), play a pivotal role in maintaining mucosal integrity by modulating various functions of the gastrointestinal (GI) tract, and PGE2 is most effective in these actions. The PGE2 receptor is classified into 4 specific G-protein coupled subtypes, EP1-EP4, and their distribution accounts for the multiple effects of this prostanoid. PGE2 prevents acid-reflux esophagitis and indomethacin-induced gastric lesions through EP1 receptors, while endogenous PGs protect the stomach against cold restraint stress me...
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
ConclusionsGastrointestinal complications are not uncommon in LTx recipients and may be serious; therefore, early detection and appropriate treatment are imperative. Surgical management is required for some complications, but most can be managed medically.
Source: Surgery Today - Category: Surgery Source Type: research
Authors: Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Okayama T, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y Abstract Proton pump inhibitors (PPIs) are widely used to treat gastro-esophageal reflux and prevent gastric ulcers, and have been considered as low risk. However, recent studies have identified possible associations between PPI use and gut microbiota, suggesting that PPIs use increases the risk of enteric infections, including Clostridium difficile infection. To investigate gut microbiota in Japanese PPIs users, we cond...
Source: Journal of Clinical Biochemistry and Nutrition - Category: Nutrition Tags: J Clin Biochem Nutr Source Type: research
AbstractAlthough proton pump inhibitors (PPIs) have been used widely, acid-related diseases are still associated with a huge burden on the health care system. Recently, the efficacy and safety of a new acid suppressant named vonoprazan in the treatment of acid-related diseases have been evaluated by a series of studies. As a novel potassium-competitive acid blocker, vonoprazan may provide reversible acid suppression by preventing K+ from binding to gastric H+/K+-ATPase. It has been clinically used for the short-term treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease andHelicobacter pylori (H. pylori)...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Researchers have succeeded in identifying the mechanisms involved in what is known as the acid pump, which at the cellular level pumps acid into the stomach -- in some cases leading to gastric ulcers and gastroesophageal reflux disease.
Source: ScienceDaily Headlines - Category: Science Source Type: news
(Aarhus University) Researchers at Aarhus University in Denmark have succeeded in identifying the mechanisms involved in what is known as the acid pump, which at the cellular level pumps acid into the stomach -- in some cases leading to gastric ulcers and gastroesophageal reflux disease. The research results emanate from Jens Chr. Skou's sodium-potassium pump, for which he was awarded the Nobel Prize twenty years ago.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news
We present a case series of four children who were initially diagnosed with infectious esophagitis, gastroesophageal reflux disease or gastric ulcer, who had no eosinophilic infiltration of the esophagus, but subsequently developed symptoms, endoscopic features and histological picture of typical EoE. We discuss mechanisms of action of PPIs of likely relevance to an increased risk of development of EoE in some patients , such as their influence on mucosal barrier function, interference with pH-related protein digestion by pepsin, and antigen processing by immune cells. (Acta gastro-enterol. belg., 2016, 79, 245-250). P...
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
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