Proton pump inhibitors linked to increased risk of depression due to destructive effects on gut microbiota

(Natural News) New research published in the journal Psychotherapy and Psychosomatics has identified a strong and seemingly causal link between proton pump inhibitor (PPI) drugs for stomach acid reduction and severe depression, which researchers say is probably a result of the way these drugs severely disrupt the gut microbiome. The study’s comparative analysis looked at...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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ConclusionsPE and RT are well-tolerated, feasible, and effective for older adults, though treatment gains were not maintained at follow-up.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
AbstractPostpartum depression is one of the most common complications of childbirth. Untreated postpartum depression can have substantial adverse effects on the well-being of the mother and child, negatively impacting child cognitive, behavioral, and emotional development with lasting consequences. There are a number of therapeutic interventions for postpartum depression including pharmacotherapy, psychotherapy, neuromodulation, and hormonal therapy among others, most of which have been adapted from the treatment of major depressive disorder outside of the peripartum period. Current evidence of antidepressant treatment for...
Source: CNS Drugs - Category: Neurology Source Type: research
Last week a committee of the U.S. Food and Drug Administration (FDA) recommended in a 14-2 vote that the agency approve the use of a nasal spray form of esketamine (a specific type of ketamine) for the treatment of treatment-resistant depression and certain other types of depression. Treatment-resistant depression is when clinical depression fails to respond to multiple (at least two) attempts to treat it with at least two different types of medications or psychotherapy over the course of a year or longer. If the FDA ends up approving the drug — and we believe they will — it will offer new hope for people with ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Depression Disorders General Medications Treatment esketamine ketamine for depression Spravato Suicide TRD Treatment Resistant Depression Treatment-resistant Source Type: blogs
Yesterday, I had a full roster of clients, and it seemed that a common theme came up with many of them: the lack of purpose in their lives.It is easy to lose one's way in life and become depressed and anxious.Doctors tell people that their depression is related to problems with the neurotransmitters in their brains and that anti-depressants will help. Sometimes they do somewhat, but anti-depressants do not get to the deeper issue which is a lack of purpose and meaning in one's life. What to do about that?A lack of purpose and meaning in one's life is best addressed by a conversation with someone who is trusted, who underst...
Source: Markham's Behavioral Health - Category: International Medicine & Public Health Authors: Source Type: blogs
Journal of Personality Disorders, Ahead of Print.
Source: Journal of Personality Disorders - Category: Psychiatry Authors: Source Type: research
Journal of Personality Disorders, Ahead of Print.
Source: Journal of Personality Disorders - Category: Psychiatry Authors: Source Type: research
Conditions:   Self Harm;   Suicide, Attempted;   Emotional Instability;   Borderline Personality Disorder Interventions:   Behavioral: Psychotherapy;   Other: Pre-intervention testing Sponsors:   Haukeland University Hospital;   University of Bergen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Stereoelectroencephalography (SEEG) vs.Mindstrong HealthMood Monitoring via Invasive Brain Recordings or Smartphone SwipesWhich Would You Choose?That's not really a fair question. The ultimate goal of invasive recordings is one of direct intervention, by delivering targeted brain stimulation as a treatment. But first you have to establish a firm relationship between neural activity and mood. Well, um, smartphone swipes (the way you interact with your phone) aim to establish a firm relationship between your “digital phenotype” and your mood. And then refer you to an app for a precision intervention. Or to your t...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs
Authors: Rachid F Abstract Major depressive disorder is a highly prevalent and profoundly disabling psychiatric disorder with significant morbidity and mortality and it is very often resistant to antidepressants, electroconvulsive therapy and psychotherapy. Therapeutic alternatives include repetitive transcranial magnetic stimulation which may be an effective choice for treatment-resistant depression but requires prolonged treatments for at least four to six weeks. Shorter exposure to this technique might be more advantageous for certain cases. The purpose of this review is to describe and discuss studies that have...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
CONCLUSIONS:: The order in which CBT and antidepressant medication were sequentially combined did not appear to affect outcomes. Addition of an antidepressant is an effective approach to treating residual symptoms for patients who do not achieve remission with CBT, as is adding CBT after antidepressant monotherapy. Patients who do not respond to one treatment modality warrant consideration for addition of the alternative modality. PMID: 30764648 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
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