UCLA Medical Center doctor under investigation in organ harvesting case
(Natural News) Little Cole Hartman was dealt a bad hand right from the beginning. Born with fragile X syndrome, he had both physical and mental disabilities. When his mom died while he was just a toddler, he was adopted by Jeremy Hartman and his wife Elizabeth. Then, when he was just 8 years old, his...
ConclusionsEE is a parental feature that is possible to modulate and seems to be related to behavior problems in ID individuals. More research should be carried on to create interventions to reduce this attitude in parents of ID individuals.
Publication date: Available online 15 September 2018Source: Advances in Biological RegulationAuthor(s): Hervé Moine, Nicolas VitaleAbstractFine-tuned regulation of new proteins synthesis is key to the fast adaptation of cells to their changing environment and their response to external cues. Protein synthesis regulation is particularly refined and important in the case of highly polarized cells like neurons where translation occurs in the subcellular dendritic compartment to produce long-lasting changes that enable the formation, strengthening and weakening of inter-neuronal connection, constituting synaptic plastic...
There is a need to examine health care utilization of individuals with the rare conditions muscular dystrophies, spina bifida, and fragile X syndrome. These individuals have a greater need for health care services, particularly inpatient admissions. Prior studies have not yet assessed 30-day all-cause readmission rates.
ConclusionsThese results suggest that appropriate social gaze behavior can be successfully taught to boys with FXS using a standardized behavioral skills training approach. Future studies will need to evaluate whether younger children with FXS might benefit from this treatment, and/or whether more naturalistic forms of behavioral skills training might be beneficial, before social gaze avoidance becomes established i n the child’s repertoire.Trial registrationClinicalTrials.gov,NCT02616796. Registered 30 November 2015.
This article is protected by copyright. All rights reserved. PMID: 30132892 [PubMed - as supplied by publisher]
Mutations in the fragile X mental retardation 1 gene (FMR1) cause the most common inherited human autism spectrum disorder. FMR1 influences messenger RNA (mRNA) translation, but identifying functional targets has been difficult. We analyzed quiescent Drosophila oocytes, which, like neural synapses, depend heavily on translating stored mRNA. Ribosome profiling revealed that FMR1 enhances rather than represses the translation of mRNAs that overlap previously identified FMR1 targets, and acts preferentially on large proteins. Human homologs of at least 20 targets are associated with dominant intellectual disability, and 30 ot...
Conclusions: Critical gaps in the literature are highlighted. Research in this area is especially limited for Down syndrome and fragile X syndrome. Future directions for taking learning theories into account in interventions for children with intellectual disability are discussed, with a focus on the importance of language input. PMID: 30120444 [PubMed - in process]
Conclusions Critical gaps in the literature are highlighted. Research in this area is especially limited for Down syndrome and fragile X syndrome. Future directions for taking learning theories into account in interventions for children with intellectual disability are discussed, with a focus on the importance of language input.
Journal of Intellectual Disability Research, EarlyView.