Teen DENIED life-saving double lung transplant after testing positive for marijuana

(Natural News) Just next door in the state of Colorado, its use is commonly recommended to patients to help relieve pain and provide relief from disease. But in Utah, cannabis consumption is apparently not only frowned upon, but it could end up actually barring a patient’s access to life-saving medical treatments. This is exactly what...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Leukemia relapse occurring in donor cells, so called donor cell leukemia (DCL) after allogeneic hematopoietic stem cell transplantation has been previously reported in the literature. Some authors have suggested that the development of DCL is perhaps a more common occurrence than traditionally thought. Donor cell myeloma (DCM) seems to be less frequent than DCL. This 46-year old male when first seen in 2000 was diagnosed with stage IIIa multiple myeloma. A monoclonal IgA kappa spike was recorded at diagnosis. Treatment with melphalan and prednisone was delivered every four to six weeks for a total of 22 courses. Fourty mon...
Source: Blood - Category: Hematology Authors: Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence Source Type: research
Introduction: Pts with AML often present with hyperleukocytosis, defined with a white blood cell count (WBC) of>50 or>100 x 109/L. Hyperleukocytosis is associated with higher rates of complications and death especially when associated with clinical leukostasis. There are no clear guidelines outlining the best cytoreductive strategy and the use of leukapheresis is based on institutional practice. Limited data is available regarding characteristics of AML pts with hyperleukocytosis, treatment patterns, short and long-term clinical outcomes.Methods: Data were collected retrospectively from 12 centers in the United State...
Source: Blood - Category: Hematology Authors: Tags: 615. Acute Myeloid Leukemia: Commercially Available Therapy, excluding Transplantation: Poster III Source Type: research
CONCLUSIONSIn this pre-planned interim analysis of our phase II study, we show that DKRd is a highly effective and well tolerated combination therapy for newly diagnosed multiple myeloma patients. Based on small numbers of patients who have completed the planned DKRd cycles and been evaluated by bone marrow-based MRD and peripheral-blood based assays, we show that highly sensitive protein assays may allow longitudinal MRD tracking in peripheral-blood. At the meeting, we will present updated results using longitudinal testing with MALDI TOF-MS and QTOF-MS on the entire cohort.DisclosuresLandgren: Takeda: Consultancy, Member...
Source: Blood - Category: Hematology Authors: Tags: 653. Myeloma: Therapy, excluding Transplantation: Poster II Source Type: research
Introduction: Hematopoietic cell transplantation (HCT) involves the transplantation of hematopoietic stem and progenitor cells (HSCs/HPCs) from autologous or histocompatible allogeneic donors. HCT restores bone marrow function after conditioning, high dose chemotherapy (Bendall, Cytokine &Growth Factor Reviews 2014). G-CSF, which prevents CIN, is also used to mobilize HSCs/HPCs (CD34+ cells) prior to HCT. Plinabulin (Plin), a small molecule with immune-enhancing anticancer activity, is under clinical development for cancer treatment and CIN prevention. Plin has anticancer activity in lung cancer (NSCLC) patients (pts) ...
Source: Blood - Category: Hematology Authors: Tags: 711. Cell Collection and Processing: Poster I Source Type: research
Conclusions:We present the largest experience in EMH without associated MPN, in adults. We describe associated conditions and elaborate further on "idiopathic" EMH (n=12), which often represented an incidental discovery during evaluation of unrelated symptoms. None of the patients with idiopathic EMH harbored occult malignancies or subsequently developed MPN or other myeloid malignancies. Our observations do not support undertaking extensive investigations targeting MPN or other malignancies in idiopathic EMH and simple monitoring might be adequate.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 634. Myeloproliferative Syndromes: Clinical Source Type: research
Conclusion: Transplanted patients had presence of pain that was different in its nature, but degree of the pain which interferes with the performance of various activities does not show statistically significant differences between the study and control group. Perhaps it can be assumed due to the strict rules of the lifestyle after lung transplantation in these patients, but further research are needed.References: 1. Zovko T, Karabatic S, Sajnic A, Repovecki S, Basara L, Pavlisa G, Jakopovic M, Samarzija M. Quality of life of patients after lung transplantation. ERJ.2017;50(s61):PA609.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Nurses Source Type: research
ConclusionPreoperative thoracic epidural placement provides improved analgesia without increased morbidity following lung transplantation.This article is protected by copyright. All rights reserved.
Source: Clinical Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
This article provides a review of perioperative interventions that have been shown to impact the perioperative course after lung transplantation.
Source: Critical Care Clinics - Category: Intensive Care Authors: Source Type: research
Transplant Infectious Disease, EarlyView.
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Source Type: research
Publication date: Available online 6 September 2018Source: Anaesthesia &Intensive Care MedicineAuthor(s): Mark Buckland, Bronwyn Scarr, Chris DurkinAbstractHeart and lung transplantation rates continue to rise with median survival rates of 11 and 7.4 years, respectively, with transplantation becoming the definitive therapy for end-stage disease of each system. Indications for lung transplantation are categorized as suppurative, obstructive, restrictive and pulmonary vascular. Surgical options include single lung, bilateral sequential single lung and heart–lung transplantation. Each has their own intraoperative ch...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
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