Intrapartum Sildenafil in Laboring Mothers
Conditions: Neonatal Asphyxia; Intrapartum Fetal Distress; Development, Infant; Intrapartum Asphyxia Interventions: Drug: Sildenafil 50 mg Oral Tablet; Drug: Placebo Oral Tablet Sponsors: University of Alabama at Birmingham; University Teaching Hospital, Lusaka, Zambia; Egerton University; Cameroon Baptist Convention Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis
Conditions: Neurocysticercosis Interventions: Drug: albendazole and praziquantel; Drug: Albendazole Sponsors: Dario Scaramuzzi; Muhimbili University of Health and Allied Sciences; National Institute for Medical Research, Tanzania; Sokoine University of Agriculture; University of Zambia; University Ghent Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Assessing the Impact of a Digital VMMC Platform
Conditions: Voluntary Medical Male Circumcision Interventions: Other: VMMC NEXUS Digital application Sponsors: University of Alabama at Birmingham; Centre for Infectious Disease Research in Zambia Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials
RISEinFAMILY project: the integration of families at neonatal intensive care units (NICUs) to empower them as primary caregivers: study protocol for a stepped wedge cluster controlled trial
This study aims to evaluate the scalability and adaptation of FICare across a broader range of geographical and sociocultural contexts and address its sustainability. Furthermore, it seeks to compare the RISEinFAMILY model with standard care, examining differences in short-term newborn outcomes, family mental health, and professional satisfaction.Trial registrationClinicalTrials.gov NCT06087666. Registered on 17 October 2023. Protocol version: 19 December 2022; version 2.2. (Source: Trials)
Source: Trials - April 10, 2024 Category: Research Source Type: clinical trials
Parasite Clearance and Protection From Infection (PCPI) in Zambia
Conditions: Malaria Interventions: Drug: SP (Macleods Pharmaceuticals Ltd); Drug: AS (Guilin Pharmaceuticals) Sponsors: London School of Hygiene and Tropical Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials
Master statistical analysis plan: attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia
AbstractThis manuscript is a master statistical analysis plan for each of three-cluster randomized controlled trials to evaluate the efficacy of attractive targeted sugar baits (ATSB) described in an already published protocol. The master SAP contains an overarching plan for all three trials, which can be adapted to trial-specific circumstances. The primary objective of the trials is to evaluate the efficacy of ATSB in the presence of universal vector control coverage with insecticide-treated nets (ITN) or indoor residual spraying (IRS) after two transmission seasons on clinical malaria incidence as compared with universal...
Source: Trials - November 29, 2023 Category: Research Source Type: clinical trials
AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)
Conditions: Cervical Cancer; Kaposi Sarcoma; Non Hodgkin Lymphoma Interventions: Other: ARROW strategies; Other: One-time education Sponsors: Implenomics; Population Council; Society of Clinical and Radiation Oncologists of Zambia (ZASCRO); RTI International Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 22, 2023 Category: Research Source Type: clinical trials
