Urachal yolk sac tumor penetrating the bladder as a diagnostic challenge: a case report and review of the literature
Yolk sac tumor (YST) is a germ cell tumor. It is primarily located in the gonads but can also occur extragonadally (extragonadal yolk sac tumor - EGYST), most commonly in the pelvis, retroperitoneum or mediast... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - January 14, 2022 Category: Pathology Authors: Vladim ír Šámal, Tomáš Jirásek, Vít Paldus, Igor Richter and Ondřej Hes Tags: Case Report Source Type: research

Abdominal wall yolk sac tumor in a child
We report a case of large yolk sac tumor located in the anterior abdominal wall just below xiphisternum in a 20-month-old girl diagnosed by raised serum alpha fetoprotein levels and fine-needle aspiration cytology. Preoperative chemotherapy helped in reducing its size allowing wide resection and primary wound closure. This case is reported for the unusual location and role of chemotherapy in management. (Source: Journal of Indian Association of Pediatric Surgeons)
Source: Journal of Indian Association of Pediatric Surgeons - January 11, 2022 Category: Surgery Authors: Manasa Reddy Pritam Singha Roy Prema Menon Shailesh Solanki Shruti Gupta Ram Samujh Amita Trehan Source Type: research

Splenic rupture revealing metastasis of a yolk sac tumor
We report a rare entity in adults with an exceptional secondary complication. This is a case of a splenic localization of a yolk sac tumor responsible for a splenic rupture in a 52-year-old man.PMID:34973818 | DOI:10.1016/j.annpat.2021.12.002 (Source: Annales de Pathologie)
Source: Annales de Pathologie - January 2, 2022 Category: Pathology Authors: Lova Carole Andrianirina Gerlinde Averous V éronique Lindner Source Type: research

Splenic rupture revealing metastasis of a yolk sac tumor
We report a rare entity in adults with an exceptional secondary complication. This is a case of a splenic localization of a yolk sac tumor responsible for a splenic rupture in a 52-year-old man.PMID:34973818 | DOI:10.1016/j.annpat.2021.12.002 (Source: Annales de Pathologie)
Source: Annales de Pathologie - January 2, 2022 Category: Pathology Authors: Lova Carole Andrianirina Gerlinde Averous V éronique Lindner Source Type: research

Malignant Melanoma Arising in a Primary Mediastinal Teratoma: Case Report of a Rare Phenomenon and Review of the Literature
We report the case of a 21-year-old male patient who presented with anterior mediastinal mass that on initial biopsy and workup revealed a mediastinal mixed GCT with teratoma and yolk sac components. Following chemotherapy, the resected mass demonstrated residual teratoma with malignant transformation into melanocytic, neuroectodermal, and undifferentiated sarcomatous elements. The patient rapidly developed metastases to the lung, liver, spleen, and spine. Biopsy of the bone marrow and liver confirmed metastatic dissemination by melanocytic transformed GCT. Molecular analysis for BRAF mutation was negative. The rapid multi...
Source: Pathology Case Reviews - January 1, 2022 Category: Pathology Tags: Case Reviews Source Type: research

Yolk Sac Tumor Arising in Uterine Carcinosarcoma With Endometrioid and Serous Components: A Case Report With Immunohistochemical Analysis
Yolk sac tumor of the endometrium is an uncommon neoplasm. Here we report a case of yolk sac tumor arising in a uterine carcinosarcoma, with the carcinomatous component showing both endometrioid and serous components, and the sarcomatous component showing homologous (spindled) differentiation. The yolk sac tumor showed predominant glandular configuration and was present admixed with the epithelial components. Extensive immunostaining was performed to narrow the differential diagnosis, including potentially therapeutic testing for HER-2. To our knowledge, this is the first case of carcinosarcoma with this mix of epithelial ...
Source: International Journal of Gynecological Pathology - December 17, 2021 Category: Pathology Tags: Pathology of the Corpus: Case Reports Source Type: research

Pineal Yolk Sac Tumor Producing α-Fetoprotein Detected by 68Ga-FAPI PET/MRI
This study reported a case of pineal YST with α-fetoprotein production revealed by 18F-FDG and 68Ga-FAPI PET/MRI. In the PET images, 68Ga-FAPI showed a far better tumor-to-background ratio than 18F-FDG in the pineal YST because there is little 68Ga-FAPI uptake in the brain. This case indicates that 68Ga-FAPI PET/MRI may be a useful tool for evaluating intracranial YST and other types of tumors in central nervous system. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - December 16, 2021 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research

Double primary germ cell tumor in a 45 year old woman: one case report and literature review
Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.PMID:34900077 | PMC:PMC8661071 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - December 13, 2021 Category: Pathology Authors: Fan Yang Lin Kang Huanfen Zhao Source Type: research