Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite
In this study, we identified an unknown metabolite of the anaesthetic drug lidocaine, which is metabolised by HLM. By screening for lidocaine metabolic activity in five types of foods (blue cheese, shiitake mushroom, natto, yoghurt, and dry yeast), we found that bacteria isolated from natto reproduced the lidocaine metabolic reaction that occurs in HLM. A fraction containing the unknown lidocaine metabolite was prepared through mass cultivation of a Bacillus subtilis standard strain, ethyl acetate extraction, open column chromatography, and HPLC purification. We identified the unknown metabolite as 3-(2,6-dimethylphenyl)-1...
Source: Chemical and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Sho Hori Hikari Taniguchi Sota Yoshimura Kanako Takeda Ryusei Yamashita Atsushi Kimishima Kazuo Harada Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
Iodine status and determinants in adults in Norway - results from a population-based health examination survey (The HUNT Study)
CONCLUSION: Iodine status was adequate in older adults but mildly deficient in adults under 55 years. Milk intake, supplement use and use of thyroid medication are important determinants of iodine intake in Norway.PMID:38571917 | PMC:PMC10989228 | DOI:10.29219/fnr.v68.9761 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Marianne Hope Abel Torunn Holm Totland Kristin Holvik Anne Lise Brants æter Steinar Krokstad Bj ørn Olav Åsvold Haakon E Meyer Source Type: research
