The changes on salivary flow rates, buffering capacity and chromogranin A levels in adults after bariatric surgery
ConclusionAccording to the results, this study suggests that individuals undergoing BS may exhibit altered salivary buffering capacity and reduced unstimulated salivary flows in the presence of xerostomia. Additionally, the findings suggest that elevated concentration of salivary CHGA might be associated, in part, with salivary gland hypofunction.Clinical relevanceThe clinical significance of this study lies in highlighting the changes in salivary functions after BS. The identified salivary alterations might be attributed to adverse effects of BS such as vomiting, gastroesophageal reflux, and dehydration. Understanding the...
Source: Clinical Oral Investigations - February 21, 2024 Category: Dentistry Source Type: research
A fast and robust constraint-based online re-optimization approach for automated online adaptive intensity modulated proton therapy in head and neck cancer
Phys Med Biol. 2024 Feb 19. doi: 10.1088/1361-6560/ad2a98. Online ahead of print.ABSTRACTObjective - In head-and-neck cancer intensity modulated proton therapy (IMPT), adaptive radiotherapy is currently restricted to offline re-planning, mitigating the effect of slow changes in patient anatomies. Daily online adaptations can potentially improve dosimetry. Here, a new, fully automated online re-optimization strategy is presented. In a retrospective study, this online re-optimization approach was compared to our trigger-based offline re-planning (offlineTB re-planning) schedule, including extensive robustness analyses.&#...
Source: Physics in Medicine and Biology - February 19, 2024 Category: Physics Authors: Michelle Oud Sebastiaan Breedveld Jesus Rojo-Santiago Marta Krystyna Gi żyńska Michiel Kroesen Steven Habraken Zolt án Perkó Ben J M Heijmen Mischa S Hoogeman Source Type: research
A fast and robust constraint-based online re-optimization approach for automated online adaptive intensity modulated proton therapy in head and neck cancer
Phys Med Biol. 2024 Feb 19. doi: 10.1088/1361-6560/ad2a98. Online ahead of print.ABSTRACTObjective - In head-and-neck cancer intensity modulated proton therapy (IMPT), adaptive radiotherapy is currently restricted to offline re-planning, mitigating the effect of slow changes in patient anatomies. Daily online adaptations can potentially improve dosimetry. Here, a new, fully automated online re-optimization strategy is presented. In a retrospective study, this online re-optimization approach was compared to our trigger-based offline re-planning (offlineTB re-planning) schedule, including extensive robustness analyses.&#...
Source: Physics in Medicine and Biology - February 19, 2024 Category: Physics Authors: Michelle Oud Sebastiaan Breedveld Jesus Rojo-Santiago Marta Krystyna Gi żyńska Michiel Kroesen Steven Habraken Zolt án Perkó Ben J M Heijmen Mischa S Hoogeman Source Type: research
The Association of Salivary Flow Rate and Sleep Quality among Head and Neck Cancer Survivors after Radiotherapy
This study aimed to explore the role of salivary flow in the oral he... (Source: BMC Oral Health)
Source: BMC Oral Health - February 19, 2024 Category: Dentistry Authors: Yen-Wen Shen, Wen-Chen Wang, Nan-Chin Lin, Valendriyani Ningrum, Tzong-Ming Shieh and Yin-Hwa Shih Tags: Research Source Type: research
The individualized delineation of clinical target volume for primary nasopharyngeal carcinoma based on invasion risk of substructures: a prospective, real-word study with a large population
CONCLUSION: Our individualized CTV delineation method can achieve favorable local tumor control and long-term survival outcomes with acceptable late toxicities.PMID:38367938 | DOI:10.1016/j.radonc.2024.110154 (Source: Cancer Control)
Source: Cancer Control - February 17, 2024 Category: Cancer & Oncology Authors: Xiaohui Wang Nan Huang Pui Lam Yip Jing Wang Runda Huang Zhuang Sun Dehua Kang Qian He Xiaowu Deng Chong Zhao Melvin L K Chua Fei Han Source Type: research
The individualized delineation of clinical target volume for primary nasopharyngeal carcinoma based on invasion risk of substructures: a prospective, real-word study with a large population
CONCLUSION: Our individualized CTV delineation method can achieve favorable local tumor control and long-term survival outcomes with acceptable late toxicities.PMID:38367938 | DOI:10.1016/j.radonc.2024.110154 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 17, 2024 Category: Radiology Authors: Xiaohui Wang Nan Huang Pui Lam Yip Jing Wang Runda Huang Zhuang Sun Dehua Kang Qian He Xiaowu Deng Chong Zhao Melvin L K Chua Fei Han Source Type: research
The individualized delineation of clinical target volume for primary nasopharyngeal carcinoma based on invasion risk of substructures: a prospective, real-word study with a large population
CONCLUSION: Our individualized CTV delineation method can achieve favorable local tumor control and long-term survival outcomes with acceptable late toxicities.PMID:38367938 | DOI:10.1016/j.radonc.2024.110154 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 17, 2024 Category: Radiology Authors: Xiaohui Wang Nan Huang Pui Lam Yip Jing Wang Runda Huang Zhuang Sun Dehua Kang Qian He Xiaowu Deng Chong Zhao Melvin L K Chua Fei Han Source Type: research
Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model
CONCLUSION: The study provided a new potential therapeutic strategy for the treatment of xerostomia by re-engineering radiated SG using GMSCs.PMID:38365799 | DOI:10.1186/s13287-024-03659-7 (Source: Cell Research)
Source: Cell Research - February 16, 2024 Category: Cytology Authors: Hagar M Zayed Nevine H Kheir El Din Ashraf M Abu-Seida Asmaa A Abo Zeid Ola M Ezzatt Source Type: research
Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model
CONCLUSION: The study provided a new potential therapeutic strategy for the treatment of xerostomia by re-engineering radiated SG using GMSCs.PMID:38365799 | PMC:PMC10874004 | DOI:10.1186/s13287-024-03659-7 (Source: Cancer Control)
Source: Cancer Control - February 16, 2024 Category: Cancer & Oncology Authors: Hagar M Zayed Nevine H Kheir El Din Ashraf M Abu-Seida Asmaa A Abo Zeid Ola M Ezzatt Source Type: research
Development and Pilot Testing of an Algorithm-Based Approach to Anticholinergic Deprescribing in Older Patients
ConclusionsThe approach was well received by the participating physicians and might support standardized anticholinergic deprescribing. (Source: Drugs and Aging)
Source: Drugs and Aging - February 6, 2024 Category: Geriatrics Source Type: research
