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Image Case Report: Glandular Swelling
The Case A 47-year-old woman presented with a one-year history of bilateral submandibular gland swelling, mild symptoms of xerostomia and xerophthalmia and arthralgias in her fingers. A review of systems was otherwise unremarkable. On physical examination, her submandibular glands on both sides were enlarged and had a firm texture. Her parotid glands were normal, as... (Source: The Rheumatologist)
Source: The Rheumatologist - November 8, 2023 Category: Rheumatology Authors: Hung Vo, MD, Zhichun Lu, MD, & Eugene Kissin, MD Tags: Conditions Other Rheumatic Conditions Sjögren’s Disease case report glandular swelling IgG4 related disease image case report Salivary gland ultrasonography Sjögren's disease Ultrasound Source Type: research

Mesenchymal stem cell-derived HGF attenuates radiation-induced senescence in salivary glands via compensatory proliferation
Head and neck cancer accounts for more than 550 000 cases annually worldwide [1] of with 70% of patients receiving radiotherapy. A common severe side effect of radiotherapy is hyposalivation and a consequent dry mouth sensation (xerostomia) which is often very difficult to treat [2]. The major cause of this side effect is the often unavoidable exposure of the salivary glands (SG) to radiation due to their position relative to the tumor within the radiotherapy treatment plan. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - November 3, 2023 Category: Radiology Authors: A.A. Soto-Gamez, M. van Es, E. Hageman, S.A. Serna-Salas, H. Moshage, M. Demaria, S. Pringle, R.P. Coppes Tags: Original Article Source Type: research

Treatment planning comparison for head and neck cancer between photon, proton, and combined proton-photon therapy - from a fixed beam line to an arc
CONCLUSION: CPPT for HNC needs adaptive treatments. Increasing proton beam flexibility in CPPT, either by using a gantry or an upright-positioned patient, improves treatment plan quality. However, the photon component is substantially reduced, therefore, the balance between improved plan quality and costs must be further determined.PMID:37913953 | DOI:10.1016/j.radonc.2023.109973 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 1, 2023 Category: Radiology Authors: Florian Amstutz Reinhardt Krcek Barbara Bachtiary Damien C Weber Antony J Lomax Jan Unkelbach Ye Zhang Source Type: research

Unusual Gingival Presentation Following Treatment With Pembrolizumab: A Case Report
Immune checkpoint PD-1 inhibitors such as pembrolizumab plus gemcitabine, vinorelbine, and liposomal doxorubicin (pembro-GVD) has demonstrated efficacy in second-line therapy for relapsed/refractory classical Hodgkin lymphoma (cHL). Although generally well tolerated, pembrolizumab could lead to immune-related adverse events (irAEs) such as rash, fatigue, hyperthyroidism, pneumonitis, hepatitis, and colitis. Oral irAEs are not uncommon among immune checkpoint inhibitors which include xerostomia, dysgeusia, lichenoid reactions and mucositis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 1, 2023 Category: ENT & OMF Authors: ANNU SINGH, JENNA MARCINCZYK, JOSEPH HURYN, CHERRY ESTILO Source Type: research

Supraglottic Jet Oxygenation and Ventilation to Minimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under Deep Sedation: A 3-Arm Randomized Controlled Trial
CONCLUSIONS: SJOV via WNJ effectively reduces the incidence of hypoxia during FB under deep sedation.PMID:37874765 | DOI:10.1213/ANE.0000000000006678 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - October 24, 2023 Category: Anesthesiology Authors: Juan Wei Xiaowei Zhang Keting Min Huanping Zhou Xuan Shi Huimin Deng Wei Mo Huafeng Wei Yang Gu Xin Lv Source Type: research