Mpox-associated supraglottitis in an immunocompetent, reportedly sexually abstinent child
Proc (Bayl Univ Med Cent). 2024 Feb 29;37(3):482-484. doi: 10.1080/08998280.2024.2314408. eCollection 2024.ABSTRACTMpox is a double-stranded DNA virus of the Orthopoxvirus genus related to smallpox virus endemic to Africa with more than 16,000 cases reported in nonendemic countries in 2022. Classically associated with adult men who have sex with men (MSM), Mpox was once labeled a public health emergency by the World Health Organization as concerning to the general population. Supraglottitis is a rare complication of Mpox that is underreported in the literature and presents a potential airway emergency. Prompt identificatio...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Matthew Mitchell Mopileola Tomi Adewumi Lauren Welby Berra Randall Holdgraf Source Type: research

Treatment adherence and adverse event management in chronic lymphocytic leukemia: challenges and strategies for the future
We describe how such a program can be designed and implemented.PMID:38629382 | DOI:10.1080/17512433.2024.2344665 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - April 17, 2024 Category: Drugs & Pharmacology Authors: Maurlia D Upchurch Benyam Muluneh Source Type: research

Understanding the views of adult migrants around catch-up vaccination for missed routine immunisations to define strategies to improve coverage: A UK in-depth interview study
CONCLUSIONS: The major barrier to adult catch-up vaccination for missed routine immunisations and doses in migrant communities in the UK is the limited opportunities, recommendations or tailored vaccination information presented to migrants by health services. This could be improved with financial incentives for provision of catch-up vaccination in UK primary care, alongside training of healthcare professionals to support catch-up immunisation and raise awareness of existing guidelines. It will also be essential to address root causes of mistrust around vaccination, where it exists among migrants, by working closely with c...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Anna Deal Alison F Crawshaw Maha Salloum Sally E Hayward Jessica Carter Felicity Knights Farah Seedat Oumnia Bouaddi Nuria Sanchez-Clemente Laura Muzinga Lutumba Lusau Mimi Kitoko Sarah Nkembi Caroline Hickey Sandra Mounier-Jack Azeem Majeed Sally Hargrea Source Type: research

Mpox-associated supraglottitis in an immunocompetent, reportedly sexually abstinent child
Proc (Bayl Univ Med Cent). 2024 Feb 29;37(3):482-484. doi: 10.1080/08998280.2024.2314408. eCollection 2024.ABSTRACTMpox is a double-stranded DNA virus of the Orthopoxvirus genus related to smallpox virus endemic to Africa with more than 16,000 cases reported in nonendemic countries in 2022. Classically associated with adult men who have sex with men (MSM), Mpox was once labeled a public health emergency by the World Health Organization as concerning to the general population. Supraglottitis is a rare complication of Mpox that is underreported in the literature and presents a potential airway emergency. Prompt identificatio...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Matthew Mitchell Mopileola Tomi Adewumi Lauren Welby Berra Randall Holdgraf Source Type: research

Rapid response teams in the Eastern Mediterranean Region: Results from the baseline survey of country-level capacities, operations and outbreak response capabilities
Volume 19, Issue 1, January 2024 . (Source: Global Public Health)
Source: Global Public Health - April 17, 2024 Category: International Medicine & Public Health Authors: Sherein ElnosserryEvans BulivaAmgad Abdalla ElkholyAmira MahboobShaffi Fazaludeen KoyaAbdinasir Abubakara World Health Organization Office for the Eastern Mediterranean Region, Cairo, Egyptb Independent public health consultant, Boston, MA, USA Source Type: research

Edge Artificial Intelligence (AI) for real-time automatic quantification of filariasis in mobile microscopy
by Lin Lin, Elena Dacal, Nuria D íez, Claudia Carmona, Alexandra Martin Ramirez, Lourdes Barón Argos, David Bermejo-Peláez, Carla Caballero, Daniel Cuadrado, Oscar Darias-Plasencia, Jaime García-Villena, Alexander Bakarjiev, Maria Postigo, Ethan Recalde-Jaramillo, Maria Flores-Chavez, Andrés Santos, María Jesús Ledesma-Carba yo, José M. Rubio, Miguel Luengo-Oroz Filariasis, a neglected tropical disease caused by roundworms, is a significant public health concern in many tropical countries. Microscopic examination of blood samples can detect and differentiate parasite species, but it is time consuming and requires ...
Source: PLoS Neglected Tropical Diseases - April 17, 2024 Category: Tropical Medicine Authors: Lin Lin Source Type: research

Global seroprevalence of Zika virus in asymptomatic individuals: A systematic review
Conclusions/SignificanceThe study highlights the high heterogeneity and gaps in the distribution of seroprevalence. The implementation of standardized protocols and the development of tests with high specificity are essential for ensuring a valid comparison between studies. Equally crucial are vector surveillance and control methods to reduce the risk of emerging and re-emerging ZIKV outbreaks, whether caused byAe.aegypti orAe.albopictus or by the Asian or African ZIKV. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 17, 2024 Category: Tropical Medicine Authors: Paola Mariela Saba Villarroel Source Type: research

Actual and Virtual Parks Benefit Quality of Life and Physical Activity: A Cluster Trial
AbstractUrban parks provide connectedness to nature as a health resilience environment for promoting health. Virtual reality can provide opportunities for urban citizens to be exposed to natural elements with health benefits. The purpose was to explore the effects of actual and virtual parks on the quality of life and physical activity of urban residents. The study design was a cluster trial. Participants were healthy adults aged 20 –50 years, recruited from three college campuses, and randomly assigned to two experimental groups (n = 30, 32) and one control group (n = 30). The intervention with virtual or actua...
Source: Journal of Urban Health - April 17, 2024 Category: Health Management Source Type: research

National trends in the treatment of adult diffuse midline gliomas: a rare clinical scenario
ConclusionsDespite being considered ineffective, chemotherapy is still administered in most adult patients diagnosed with DMG. Significant predictors of survival were Charlson-Deyo comorbidity index and race. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - April 17, 2024 Category: Cancer & Oncology Source Type: research

Adverse events of nivolumab plus ipilimumab versus nivolumab plus cabozantinib: a real-world pharmacovigilance study
ConclusionOur findings contribute to the selection and clinical management of NIVO-IPI and NIVO-CABO, which minimizes the risk of AEs for individual patients with mRCC by considering distinctive differences in the AE profiles. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - April 17, 2024 Category: Drugs & Pharmacology Source Type: research

Factors associated with malaria vaccine uptake in Nsanje district, Malawi
Malaria remains a significant global health burden affecting millions of people, children under 5 years and pregnant women being most vulnerable. In 2019, the World Health Organization (WHO) endorsed the intro... (Source: Malaria Journal)
Source: Malaria Journal - April 17, 2024 Category: Infectious Diseases Authors: Atusaye J. Simbeye, Save Kumwenda, Lauren M. Cohee, Dickens Omondi, Peninah K. Masibo, Hesborn Wao and Shehu S. Awandu Tags: Research Source Type: research

Effect of implementation of the WHO intrapartum care model on maternal and neonatal outcomes: a randomized control trial
This study aimed to determine the effects... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 17, 2024 Category: OBGYN Authors: Somayeh Abdolalipour, Shamsi Abbasalizadeh, Sakineh Mohammad-Alizadeh-Charandabi, Fatemeh Abbasalizadeh, Shayesteh Jahanfar, Fatemeh Raphi and Mojgan Mirghafourvand Tags: Research Source Type: research

Adverse events of nivolumab plus ipilimumab versus nivolumab plus cabozantinib: a real-world pharmacovigilance study
ConclusionOur findings contribute to the selection and clinical management of NIVO-IPI and NIVO-CABO, which minimizes the risk of AEs for individual patients with mRCC by considering distinctive differences in the AE profiles. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - April 17, 2024 Category: Drugs & Pharmacology Source Type: research

Plans to expand African vaccine production face steep hurdles
In March 2022, when the pandemic was still raging, the messenger RNA (mRNA) company Moderna announced it would build a $500 million plant in Kenya to manufacture half a billion doses of its COVID-19 vaccine annually. “ This is major ,” Kenyan President William Ruto said at the time. The plant would help reduce Africa’s dependence on vaccines produced elsewhere, Ruto said—a situation that had turned disastrous during the pandemic—and bring economic benefits as well. But Moderna may never break ground on the Kenya factory. On 11 April, the company said it had “paused its efforts” becau...
Source: Science of Aging Knowledge Environment - April 16, 2024 Category: Geriatrics Source Type: research

Improvement in quality of trauma care at non-tertiary hospitals in Ghana during on-hours and off-hours with a trauma intake form: A stepped-wedge cluster randomized trial
Trauma is a significant health problem globally, especially in low- and middle-income countries (LMICs). Improvements in trauma care in LMICs must overcome considerable resource restrictions. Hence, improvements in the organization and process of care are important options in light of their affordability. The World Health Organization's (WHO) Trauma Care Checklist (TCC) has been shown to improve the process of care and lower mortality for seriously injured patients at tertiary centers in both high-income countries and LMICs [1]. (Source: Injury)
Source: Injury - April 16, 2024 Category: Orthopaedics Authors: Adam Gyedu, Lord Loglo, Kofi Ablorh, Isaac Asenso Brobbey-Kyei, Peter Donkor, Charles Mock Source Type: research