Agreement about Availability of Alternative Treatments for Innovative Drugs Assessed by the EMA and HTA Organizations
In conclusion, although there was high overall agreement between the EMA and HTA organizations about whether alternative treatments exist, there were differences in the types of treatment considered. Parallel joint scientific consultations could inform drug developers about relevant alternative treatments to facilitate patient access to innovative drugs.PMID:38505926 | DOI:10.1002/cpt.3252 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 20, 2024 Category: Drugs & Pharmacology Authors: Jorge Madrid Paredes Jan-Willem Versteeg Rick A Vreman Lourens T Bloem Source Type: research
TAT-HUM: Trajectory analysis toolkit for human movements in Python
Behav Res Methods. 2024 Mar 19. doi: 10.3758/s13428-024-02378-4. Online ahead of print.ABSTRACTHuman movement trajectories can reveal useful insights regarding the underlying mechanisms of human behaviors. Extracting information from movement trajectories, however, can be challenging because of their complex and dynamic nature. The current paper presents a Python toolkit developed to help users analyze and extract meaningful information from the trajectories of discrete rapid aiming movements executed by humans. This toolkit uses various open-source Python libraries, such as NumPy and SciPy, and offers a collection of comm...
Source: Behavior Research Methods - March 20, 2024 Category: Psychiatry & Psychology Authors: Xiaoye Michael Wang Timothy N Welsh Source Type: research
Investigating Length of Stay Patterns and Its Predictors in the South Wales Trauma Network
CONCLUSION: Our finding supports prior evidence indicating elderly people are vulnerable to longer stays. Moreover, concerning the types of admission wards, patients admitted to rehabilitation wards who underwent more than 2 hospitalisations also faced an increased risk of prolonged stay. Based on these results, policymakers and healthcare providers should contemplate expanding the allocation of medical resources to this demographic to mitigate the length of stay and optimise associated healthcare costs.PMID:38505372 | PMC:PMC10949546 | DOI:10.1177/27536351241237866 (Source: Adv Data)
Source: Adv Data - March 20, 2024 Category: Epidemiology Authors: Zihao Wang Bahman Rostami-Tabar Jane Haider Mohamed Naim Javvad Haider Source Type: research
The perceived helpfulness and acceptability of a bespoke psychological therapy service for registered nurses experiencing psychological distress: A qualitative study
CONCLUSION: Participants attempted to live up to an idealized image of a nurse, generating self-stigmatizing beliefs that negatively affected their mental health. The psychological therapy service enabled participants to put their roles into perspective, that is, separate themselves from their role, be vulnerable, and develop confidence and adaptive coping strategies. Participants valued the minimal barriers and ease of access to support.IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: The complex relationship between nurse identity and the challenges of the workplace needs to be central to nurse education. Nurses can ...
Source: Adv Data - March 20, 2024 Category: Epidemiology Authors: Dean Whybrow Bethan Jones Eunice Temeng Carys Dale Chris Bundy Tessa Watts Source Type: research
How the training pathways and capacity of rural physicians inform their scope of practice: A qualitative study examining the experiences of Australian and international medical graduates in South-East New South Wales, Australia
CONCLUSION: Doctors' scope of practice is informed by their pathways into rural practice. Australian medical graduates may not gain adequate competence during expedited training programs to confidently undertake extended clinical activities. International medical graduates, however lacked the opportunities and support, to utilise their expertise in rural practice. Complementarily utilising the expertise and commitment of both AMGs and IMGs may synergistically address workforce shortages.PMID:38504461 | DOI:10.1111/ajr.13105 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - March 20, 2024 Category: Rural Health Authors: Sarath Burgis-Kasthala Suzanne Bain-Donohue Ellen Tailby Kathryn Stonestreet Malcolm Moore Source Type: research
Agreement about Availability of Alternative Treatments for Innovative Drugs Assessed by the EMA and HTA Organizations
In conclusion, although there was high overall agreement between the EMA and HTA organizations about whether alternative treatments exist, there were differences in the types of treatment considered. Parallel joint scientific consultations could inform drug developers about relevant alternative treatments to facilitate patient access to innovative drugs.PMID:38505926 | DOI:10.1002/cpt.3252 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 20, 2024 Category: Drugs & Pharmacology Authors: Jorge Madrid Paredes Jan-Willem Versteeg Rick A Vreman Lourens T Bloem Source Type: research
TAT-HUM: Trajectory analysis toolkit for human movements in Python
Behav Res Methods. 2024 Mar 19. doi: 10.3758/s13428-024-02378-4. Online ahead of print.ABSTRACTHuman movement trajectories can reveal useful insights regarding the underlying mechanisms of human behaviors. Extracting information from movement trajectories, however, can be challenging because of their complex and dynamic nature. The current paper presents a Python toolkit developed to help users analyze and extract meaningful information from the trajectories of discrete rapid aiming movements executed by humans. This toolkit uses various open-source Python libraries, such as NumPy and SciPy, and offers a collection of comm...
Source: Behavior Research Methods - March 20, 2024 Category: Psychiatry & Psychology Authors: Xiaoye Michael Wang Timothy N Welsh Source Type: research
How the training pathways and capacity of rural physicians inform their scope of practice: A qualitative study examining the experiences of Australian and international medical graduates in South-East New South Wales, Australia
CONCLUSION: Doctors' scope of practice is informed by their pathways into rural practice. Australian medical graduates may not gain adequate competence during expedited training programs to confidently undertake extended clinical activities. International medical graduates, however lacked the opportunities and support, to utilise their expertise in rural practice. Complementarily utilising the expertise and commitment of both AMGs and IMGs may synergistically address workforce shortages.PMID:38504461 | DOI:10.1111/ajr.13105 (Source: The Australian Journal of Rural Health)
Source: The Australian Journal of Rural Health - March 20, 2024 Category: Rural Health Authors: Sarath Burgis-Kasthala Suzanne Bain-Donohue Ellen Tailby Kathryn Stonestreet Malcolm Moore Source Type: research
Agreement about Availability of Alternative Treatments for Innovative Drugs Assessed by the EMA and HTA Organizations
In conclusion, although there was high overall agreement between the EMA and HTA organizations about whether alternative treatments exist, there were differences in the types of treatment considered. Parallel joint scientific consultations could inform drug developers about relevant alternative treatments to facilitate patient access to innovative drugs.PMID:38505926 | DOI:10.1002/cpt.3252 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 20, 2024 Category: Drugs & Pharmacology Authors: Jorge Madrid Paredes Jan-Willem Versteeg Rick A Vreman Lourens T Bloem Source Type: research
Agreement about Availability of Alternative Treatments for Innovative Drugs Assessed by the EMA and HTA Organizations
In conclusion, although there was high overall agreement between the EMA and HTA organizations about whether alternative treatments exist, there were differences in the types of treatment considered. Parallel joint scientific consultations could inform drug developers about relevant alternative treatments to facilitate patient access to innovative drugs.PMID:38505926 | DOI:10.1002/cpt.3252 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 20, 2024 Category: Drugs & Pharmacology Authors: Jorge Madrid Paredes Jan-Willem Versteeg Rick A Vreman Lourens T Bloem Source Type: research
Cancers, Vol. 16, Pages 1218: Contrast Clearance Analysis (CCA) to Assess Viable Tumour following Stereotactic Radiosurgery (SRS) to Brain Metastasis in Non-Small Cell Lung Cancer (NSCLC)
Conclusions: Our single-centre experience shows CCA to be feasible and useful in patients with NSCLC in cases of diagnostic uncertainty in MRI. It has helped guide treatment in the majority of patients, with subsequent outcomes following the implementation of the treatment based on the results, suggesting correct classification. Recommendations from our experience of the implementation include the careful consideration of the thin rim of the rapid contrast clearance and the timing of the CCA prior to surgery for suspected brain metastasis progression. (Source: Cancers)
Source: Cancers - March 20, 2024 Category: Cancer & Oncology Authors: Shybi Mohamedkhan Sumeet Hindocha James de Boisanger Thomas Millard Liam Welsh Philip Rich Andrew D. MacKinnon Nicholas Williams Bhupinder Sharma Nicola Rosenfelder Anna Minchom Tags: Communication Source Type: research
Updated population-level estimates of child restraint practices among children aged 0-12 years in Australia, 10 years after introduction of age-appropriate restraint use legislation
Conclusion
The findings demonstrate high levels of appropriate restraint use among children across metropolitan Sydney approximately 10 years after introduction of legislation requiring age-appropriate restraint use until age 7, however, errors in the way restraints remain common.
Implications for public health
Given the negative impact incorrect use has on crash protection, continuing high rates of incorrect use may reduce effectiveness of legislative change on injury reduction. (Source: Injury Prevention)
Source: Injury Prevention - March 20, 2024 Category: Accident Prevention Authors: Brown, J., Albanese, B., Ho, C., Elkington, J., Koppel, S., Charlton, J. L., Olivier, J., Keay, L., Bilston, L. E. Tags: Editor's choice Original research Source Type: research
REST: a preoperative tailored sleep intervention for patients undergoing total knee replacement - feasibility study for a randomised controlled trial
Conclusions
This feasibility study has demonstrated that with some amendments to processes and design, an RCT to evaluate the clinical and cost-effectiveness of the REST intervention is feasible.
Trial registration number
ISRCTN14233189. (Source: BMJ Open)
Source: BMJ Open - March 20, 2024 Category: General Medicine Authors: Bertram, W., Penfold, C., Glynn, J., Johnson, E., Burston, A., Rayment, D., Howells, N., White, S., Wylde, V., Gooberman-Hill, R., Blom, A., Whale, K. Tags: Open access, Health services research Source Type: research
Matters of time in health and illness
. (Source: Health Sociology Review)
Source: Health Sociology Review - March 20, 2024 Category: International Medicine & Public Health Authors: Mia HarrisonAnthony K J SmithSophie Adamsa Centre for Social Research in Health, University of New South Wales, Kensington, Australiab Alfred Deakin Institute of Citizenship and Globalisation, Deakin University, Burwood, Australia Source Type: research
A critical discourse analysis of older women ’s representation in housing and homelessness
A critical discourse analysis of older women’s representation in housing and homelessness Taylah Brown, Charlotte Smedley, Jacqui Cameron Housing, Care and Support, Vol. ahead-of-print, No. ahead-of-print, pp.- Despite a significant evidence base illustrating the issue of housing insecurity and homelessness experienced by women over the age of 55 in Australia [Pawson et al., 2018; Australian Institute of Health and Welfare (AIHW), 2021b; Mission Australia 2022; Per Capita 2022], there continues to be a knowledge gap in the representation of older women in current Federal and New South Wales (NSW) State Government housing...
Source: Housing, Care and Support - March 19, 2024 Category: International Medicine & Public Health Authors: Taylah Brown Charlotte Smedley Jacqui Cameron Source Type: research
