A Retrospective Cohort Study of Differential Attainment, COVID-19 and Chaos
Conditions:   Surgery;   COVID-19 Intervention:   Other: Differential attainment Sponsor:   Health Education and Improvement Wales Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2022 Category: Research Source Type: clinical trials

ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis —study protocol for an interventional randomised controlled trial
DiscussionThis trial will investigate the efficacy, safety, and cost-effectiveness of co-trimoxazole for patients with liver cirrhosis and ascites to determine whether this strategy improves clinical outcomes. Given there are no treatments that improve survival in decompensated cirrhosis outside of liver transplant, if the trial has a positive outcome, we anticipate widespread adoption of primary antibiotic prophylaxis.Trial registrationClinicalTrials.govNCT043955365. Registered on 18 April 2020. Research ethical approval was granted by the Research Ethics Committee (South Central – Oxford B; REC 19/SC/0311) and the Medi...
Source: Trials - September 27, 2022 Category: Research Source Type: clinical trials

A Feasibility Randomised Control Trial (RCT) of Aerobika TM Verses Active Cycle of Breathing Technique (ACBT) in People With Chronic Obstructive Pulmonary Disease (COPD)
Conditions:   COPD;   Bronchiolitis Intervention:   Device: OPEP Sponsors:   Hywel Dda Health Board;   Cardiff and Vale UHB;   Trudell International;   Respiratory Innovation Wales Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2022 Category: Research Source Type: clinical trials