A Feasibility Randomised Control Trial (RCT) of Aerobika TM Verses Active Cycle of Breathing Technique (ACBT) in People With Chronic Obstructive Pulmonary Disease (COPD)
Conditions:   COPD;   Bronchiolitis Intervention:   Device: OPEP Sponsors:   Hywel Dda Health Board;   Cardiff and Vale UHB;   Trudell International;   Respiratory Innovation Wales Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2022 Category: Research Source Type: clinical trials

Effectiveness, safety and cost-effectiveness of vaporized nicotine products versus nicotine replacement therapy for tobacco smoking cessation in a low-socioeconomic status Australian population: a study protocol for a randomized controlled trial
This study evaluates the effectiveness, safety and cost-effectiveness of VNPs (pod and tank device) compared with nicotine replacement therapy ([NRT] —gum or lozenge) for smoking cessation.MethodsThis is a two-arm, open-label, superiority, parallel group, randomized controlled trial (RCT) with allocation concealment and blinded outcome assessment. The RCT is conducted at the National Drug and Alcohol Research Centre at the University of New South Wales, Sydney, Australia. Participants are people who smoke daily, are interested in quitting and receive a government pension or allowance (N = 1058). Participants will be rand...
Source: Trials - September 14, 2022 Category: Research Source Type: clinical trials

uSing rolE-substitutioN In care homes to improve ORal health (SENIOR): a study protocol
DiscussionThis trial will provide evidence on how to successfully implement and sustain a Dental Care Professional-led intervention within care homes to promote access and prevention.Trial registrationISRCTN16332897. Registered on 3 December 2021. (Source: Trials)
Source: Trials - August 18, 2022 Category: Research Source Type: clinical trials

Clinical and cost-effectiveness of paramedic administered fascia iliaca compartment block for emergency hip fracture (RAPID 2) —protocol for an individually randomised parallel-group trial
DiscussionThe trial will help to determine whether paramedic administered FICB is a safe, clinically and cost-effective treatment for suspected hip fracture in the pre-hospital setting. Impact will be shown if and when clinical guidelines either recommend or reject the use of FICB in routine practice in this context.Trial registrationISRCTN15831813. Registered on 22 September 2021. (Source: Trials)
Source: Trials - August 17, 2022 Category: Research Source Type: clinical trials

Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study
This study will guide treatment decision-making and clinical practice guidelines regarding the effectiveness of various prophylactic catheter washout policies in men and women living with LTC. This research has received ethical approval from Wales Research Ethics Committee 6 (19/WA/0015).Trial registrationISRCTNISRCTN17116445. Registered prospectively on 06 November 2019 (Source: Trials)
Source: Trials - August 4, 2022 Category: Research Source Type: clinical trials

A Global Approach to Tackle Cognitive Decline
Condition:   Dementia Intervention:   Sponsors:   Chinese University of Hong Kong;   The University of New South Wales;   University of Oxford;   University College, London;   Umeå University;   Max Planck Institute for Human Development;   National University, Singapore Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 29, 2022 Category: Research Source Type: clinical trials