Self-Reported Biotin Use Increased From 1999 to 2016
WEDNESDAY, Aug. 12, 2020 -- From 1999 to 2016, the prevalence of self-reported biotin supplement use increased, especially among women and older adults, according to a research letter published in the Aug. 11 issue of the Journal of the American... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 12, 2020 Category: Pharmaceuticals Source Type: news

At High Doses, Popular Biotin Supplement Could Mask Heart Trouble
Title: At High Doses, Popular Biotin Supplement Could Mask Heart TroubleCategory: Health NewsCreated: 8/11/2020 12:00:00 AMLast Editorial Review: 8/12/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - August 12, 2020 Category: Cardiology Source Type: news

At High Doses, Popular Biotin Supplement Could Mask Heart Trouble
TUESDAY, Aug. 11, 2020 -- A growing number of older people are turning to the vitamin biotin to fortify their aging skin, hair and nails. But a new study shows how large doses of it can interfere with some vital medical tests. Biotin, or vitamin... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 11, 2020 Category: General Medicine Source Type: news

Vitamin B7 deficiency symptoms: The sign in your hair you're lacking in the vital vitamin
VITAMIN B7, also known as biotin or vitamin H, helps the body to metabolise fats, carbohydrates and protein. What's the sign in your hair you're lacking the vitamin? (Source: Daily Express - Health)
Source: Daily Express - Health - April 1, 2020 Category: Consumer Health News Source Type: news

Understanding differences in streptavidin-biotin binding
(Beckman Institute for Advanced Science and Technology) Beckman research scientist Rafael C. Bernardi recently published a paper that uses computational tools to explain the mechanism of how streptavidin and biotin binding is affected by streptavidin's tethering. The results were published in Science Advances. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 25, 2020 Category: Biology Source Type: news

Topline Results Disappoint for Biotin in Progressive MS Topline Results Disappoint for Biotin in Progressive MS
A pharmaceutical-grade biotin product (MD1003) tested for progressive MS did not meet primary or secondary endpoints in a phase 3 study designed to confirm positive results of an earlier trial.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 12, 2020 Category: Allergy & Immunology Tags: Neurology & Neurosurgery News Source Type: news

Do You Take Biotin Supplements? They Could Affect Your Medical Tests
Title: Do You Take Biotin Supplements? They Could Affect Your Medical TestsCategory: Health NewsCreated: 11/5/2019 12:00:00 AMLast Editorial Review: 11/6/2019 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - November 6, 2019 Category: Cardiology Source Type: news

The FDA wants to make the public, including health care providers, aware of biotin interference with lab tests so that patients, physicians, and laboratories can work together to help prevent adverse events.pic.twitter.com/ng8kEscf6O
The FDA wants to make the public, including health care providers, aware of biotin interference with lab tests so that patients, physicians, and laboratories can work together to help prevent adverse events. pic.twitter.com/ng8kEscf6O (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - November 5, 2019 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news

Today, the @US_FDA updated a 2017 Safety Communication to remind the public that biotin, often found in multi-vitamins, can significantly interfere with certain lab tests and cause incorrect results that may go undetected. https://go.usa.gov/xpTfk  
Today, the @US_FDA updated a 2017 Safety Communication to remind the public that biotin, often found in multi-vitamins, can significantly interfere with certain lab tests and cause incorrect results that may go undetected. https://go.usa.gov/xpTfk  (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - November 5, 2019 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news

FDA: Biotin Interference With Troponin, Lab Tests Still a Concern FDA: Biotin Interference With Troponin, Lab Tests Still a Concern
Some lab test developers have been successful at mitigating the biotin interference of their assays, but others have not yet addressed it, the FDA said in an updated safety alert.News Alerts (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - November 5, 2019 Category: Neurology Tags: Cardiology News Alert Source Type: news

FDA: Biotin Supplements Could Affect Results of Medical Tests
TUESDAY, Nov. 5, 2019 -- Biotin supplements can interfere with the results of some critical lab tests, the U.S. Food and Drug Administration warned Tuesday. The FDA is particularly concerned about biotin interference causing a falsely low result for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 5, 2019 Category: Pharmaceuticals Source Type: news

Do You Take Biotin Supplements? They Could Affect Your Medical Tests
TUESDAY, Nov. 5, 2019 -- Biotin supplements, often taken to improve hair, skin and nails, can interfere with the results of some critical lab tests, the U.S. Food and Drug Administration warned Tuesday. The FDA is particularly concerned about... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 5, 2019 Category: General Medicine Source Type: news

3D-Printed Cell Traps Help Researchers Find Cancer Cells
Researchers at Georgia Institute of Technology (Georgia Tech) are working on a method that could enable rapid and low-cost separation of tumor cells circulating in the bloodstream. The researchers developed the new approach using 3D-printed cell traps, Georgia Tech's research news team reported. According to the researchers, trapping the white blood cells – which are about the size of cancer cells – and filtering out smaller red blood cells leaves behind the tumor cells, which could then be used to diagnose the disease, potentially provide early warning of recurrence and enable research ...
Source: MDDI - November 2, 2019 Category: Medical Devices Authors: MDDI Staff Tags: 3-D Printing Source Type: news

More than good hair and clear skin: Biotin helps the body in many ways
(Natural News) Biotin has become popular these days. It’s in numerous health and beauty ads promising shiny hair, gorgeous skin, and overall wellness. While biotin supplements are available in local drugstores, there are many foods that can provide biotin. Biotin is not only good for the hair, it also offers plenty of health benefits. The health benefits... (Source: NaturalNews.com)
Source: NaturalNews.com - August 26, 2019 Category: Consumer Health News Source Type: news

Veravas Launches Product Portfolio to Mitigate Biotin Interference and Improve Diagnostic Assay Accuracy
Veravas, Inc., an emerging diagnostic company, launched a portfolio of products that can improve the accuracy of current diagnostic test results by helping laboratory professionals detect and manage... (Source: The Scientist)
Source: The Scientist - July 12, 2019 Category: Science Tags: The Scientist The Marketplace Source Type: news

Urine test for sleep apnea? Soon, says new Twin Cities diagnostics startup
Veravas is launching a suite of products in July to combat biotin interference in diagnostic tests. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 27, 2019 Category: Biotechnology Authors: Alex Wittenberg Source Type: news

Urine test for sleep apnea? Soon, says new Twin Cities diagnostics startup
Veravas is launching a suite of products in July to combat biotin interference in diagnostic tests. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 27, 2019 Category: Pharmaceuticals Authors: Alex Wittenberg Source Type: news

Susceptibility of cTn Assays to Biotin Interference Susceptibility of cTn Assays to Biotin Interference
Cardiac troponin assays may be influenced by ingestion of over-the-counter biotin, leading to overestimation or underestimation in test results. How can this be interference be overcome?American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2019 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Vector Laboratories: Is Your IHC as Easy as ABC?
With over 100K citations and counting, the avidin-biotin complex is the most popular immunhistochemistry method today. (Source: The Scientist)
Source: The Scientist - May 14, 2019 Category: Science Tags: Sponsored Videos Source Type: news

Shiny hair, stronger nails: Add these 8 biotin-rich foods to your diet
(Natural News) If you are losing hair faster than normal, you might be one of those rare individuals who suffer from a deficiency of biotin. This is easily remedied, however, by eating foods that are naturally rich in this B vitamin. Also known as vitamin B7, biotin supports the healthy growth of hair, skin, and nails.... (Source: NaturalNews.com)
Source: NaturalNews.com - April 3, 2019 Category: Consumer Health News Source Type: news

Biotin, marketed for hair and nails, could skew some medical test results, researchers warn
Biotin, or vitamin B7, is in fashion because of claims it can help people grow better hair and nails. But patients need to be aware that the supplement can interfere with some important lab tests, including those diagnosing heart attacks and thyroid issues, researchers warn. (Source: CBC | Health)
Source: CBC | Health - March 12, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Medical News Today: Does biotin help with psoriasis?
Some people use supplements of biotin, or vitamin B-7, to manage the symptoms of psoriasis. In this article, we look at the effectiveness, risks, and alternatives to biotin for psoriasis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 17, 2019 Category: Consumer Health News Tags: Psoriasis Source Type: news

Are Eggs Healthy? Here ’s What Experts Say
Eggs dominate the menus of all sorts of breakfast spots, from fast-food chains to organic cafes. But the humble egg comes with a lot of questions: Will eggs raise your cholesterol? Should you order an egg-white omelet or embrace the yolks? And what about organic eggs — are they really more nutritious? Whether you eat them every day or just occasionally, there’s plenty to learn about how to incorporate eggs into a healthy diet. Here, dietitians weigh in on what you need to know about nutrition in eggs. Are eggs healthy? Nutrition experts agree that the protein and vitamins in eggs make them a healthy option. &ld...
Source: TIME: Health - December 5, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve  Tags: Uncategorized Diet/Nutrition Source Type: news

Are Eggs Healthy? Here ’s What the Experts Say
Eggs dominate the menus of all sorts of breakfast spots, from fast-food chains to organic cafes. But the humble egg comes with a lot of questions: Will eggs raise your cholesterol? Should you order an egg-white omelet or embrace the yolks? And what about organic eggs — are they really more nutritious? Whether you eat them every day or just occasionally, there’s plenty to learn about how to incorporate eggs into a healthy diet. Here, dietitians weigh in on what you need to know about nutrition in eggs. Are eggs healthy? Nutrition experts agree that the protein and vitamins in eggs make them a healthy option. &ld...
Source: TIME: Health - December 5, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve  Tags: Uncategorized Diet/Nutrition Source Type: news

Easy Immunostaining Staining
10X the Signal at a Fraction of the CostTime is money. This is especially true of routine immunostaining assays.We are pleased to introduce you toEZ-HRPTM Polymer Detection. Features include:10-15 times more sensitive than conventional avidin-biotin detection Allows for entire staining procedure to be completed in just under 2 hours Requires less primary antibody (3-4 times less) Does not produce non-specific background staining Can be used on unfixed or chemical fixed (formalin, formaldehyde, alcohol, etc), paraffin-embedded and frozen tissue sections.Comparison of IHC images using EZ-HRP ™ Polymer vs. a c...
Source: Neuromics - July 31, 2018 Category: Neuroscience Tags: HRP-Staining. Immunofluorescence Immunonostaining Source Type: news

Case Shows Biotin Can Interfere With Multiple Endocrine Tests
MONDAY, June 4, 2018 -- Biotin, which is included in many hair, skin, and nail growth over-the-counter products, can affect multiple hormone levels, according to a case study published online May 10 in the Journal of the Endocrine Society. Heather... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 4, 2018 Category: Pharmaceuticals Source Type: news

Biotin supplements caused misleading test results, almost led to unnecessary procedure
(University of North Carolina Health Care) A new case report led by Maya Styner, M.D., of the University of North Carolina School of Medicine describes how a patient's use of a common over-the-counter biotin supplement caused clinically misleading test results and almost resulted in an unnecessary, invasive medical procedure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2018 Category: International Medicine & Public Health Source Type: news

Vitamin B7 (biotin) is essential for hair, skin and nails – and also supports metabolism, gut health, immunity and more
(Natural News) If you’re having hair and skin problems, try to eat more foods that are rich in vitamin B7 or biotin. Biotin is a B vitamin, and this group of vitamins helps with optimal bodily function. There are many “delicate, intricate pathways” like methylation, or your body’s biochemical superhighway fueled by B vitamins. Methylation... (Source: NaturalNews.com)
Source: NaturalNews.com - March 21, 2018 Category: Consumer Health News Source Type: news

Patient Taking Biotin? Be Sure to Ask if Ordering Tests Patient Taking Biotin? Be Sure to Ask if Ordering Tests
A recent safety report from the FDA warns about this vitamin's possible interference with lab tests.Medscape Internal Medicine (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - January 4, 2018 Category: Internal Medicine Tags: Internal Medicine Commentary Source Type: news

Medical News Today: All you should know about biotin deficiency
A look at deficiency in biotin, the B vitamin that helps the body convert carbohydrates. Included is detail on how it affects pregnancy and treatment. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 29, 2017 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Medical News Today: What you should know about biotin-rich foods
A look at biotin-rich foods that can be added to the diet for a range of health benefits. Included is detail on types of fish, meat, and vegetables. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 4, 2017 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

FDA Warns Biotin Can Distort Lab Tests
The FDA is warning that high doses of the vitamin B7, or biotin, in dietary supplements can interfere with hundreds of common lab tests—including some relied on by ER doctors to diagnose a heart attack. (Source: WebMD Health)
Source: WebMD Health - November 29, 2017 Category: Consumer Health News Source Type: news

Are Supplements Messing Up Your Blood Work?
  Today, the U.S. Food and Drug Administration (FDA) issued a Safety Communication titled, “The FDA Warns that Biotin May Interfere with Laboratory Tests.” The FDA is alerting the public, health care providers and laboratory personnel that biotin can interfere with certain lab tests and cause incorrect lab test results.    Some supplements, particularly those labeled for hair, skin, and nail benefits, may have high doses of biotin, which may not be clear from the label. Biotin in patient samples can cause falsely high or falsely low results, depending on the test. Clinical decisions made based on...
Source: MDDI - November 29, 2017 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news

Biotin (Vitamin B7) Supplementation Could Affect Lab Results
The FDA is reporting an increase in adverse events and one death tied to inaccurate lab results due to interference of the supplement biotin (vitamin... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 29, 2017 Category: Primary Care Source Type: news

FDA Warns Biotin May Interfere With Lab Tests, Including Troponin FDA Warns Biotin May Interfere With Lab Tests, Including Troponin
Supplementation with high doses of biotin, vitamin B7, may interfere with lab test results, including troponin testing for MI.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 28, 2017 Category: Consumer Health News Tags: Cardiology News Alert Source Type: news

The FDA Warns that Biotin May Interfere with Lab Tests: FDA Safety Communication https://go.usa.gov/xn8YY  
The FDA Warns that Biotin May Interfere with Lab Tests: FDA Safety Communication https://go.usa.gov/xn8YY  (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - November 28, 2017 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news

Biotin Interference With Routine Clinical Immunoassays Biotin Interference With Routine Clinical Immunoassays
The use of biotin supplements may impact the results of immunoassays used to evaluate endocrine function. Find out what there is to know.Endocrine Practice (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Taking Biotin May Make Biotinylated Immunoassay Results Inaccurate Taking Biotin May Make Biotinylated Immunoassay Results Inaccurate
Taking biotin supplements may interfere with immunoassays that use biotinylation in their design, yielding inaccurate test results, a new study suggests.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - September 27, 2017 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news

Biotin Supplements May Interfere with Blood Tests (CME/CE)
(MedPage Today) -- Supplements linked to false results in biotinylated assays (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - September 26, 2017 Category: Endocrinology Source Type: news

Medical News Today: Does biotin for hair growth work? Dosage and side effects
Biotin, also known as vitamin B7, is important for a healthy body. We look at the use of biotin to support hair growth, and the science behind it. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 16, 2017 Category: Consumer Health News Tags: Dermatology Source Type: news

Medical News Today: Seven health benefits of biotin
Biotin is a B-vitamin that has benefits for hair, nails and skin, to name a few. Learn more about the benefits and side effects of biotin in this article. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 31, 2017 Category: Consumer Health News Tags: Complementary Medicine / Alternative Medicine Source Type: news

A Bizarre Case of Graves Disease Due to Vitamin Treatment A Bizarre Case of Graves Disease Due to Vitamin Treatment
This unusual case highlights how biotin intake may influence thyroid function immunoassays, leading to misdiagnosis.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Medical News Today: Can Biotin Help Treat Multiple Sclerosis?
What is biotin, can it help with MS, and how might it be used? Learn about current research on biotin and other possible health benefits of this vitamin. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 14, 2017 Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

Affinity Purification Method for the Identification of Nonribosomal Peptide Biosynthetic Enzymes Using a Synthetic Probe for Adenylation Domains
A series of inhibitors have been designed based on 5′-O-sulfamoyl adenosine (AMS) that display tight binding characteristics towards the inhibition of adenylation (A) domains in nonribosomal peptide synthetases (NRPSs). We recently developed an affinity probe for A domains that could be used to facilitate the specific isolation and identification of NRPS modules. Our synthetic probe, which is a biotinylated variant of l-Phe-AMS (l-Phe-AMS-biotin), selectively targets the A domains in NRPS modules that recognize and convert l-Phe to an aminoacyl adenylate in whole proteomes. In this chapter, we describe the design and...
Source: Springer protocols feed by Protein Science - May 8, 2016 Category: Biochemistry Source Type: news

Engineered monomeric streptavidin
A novel streptavidin variant with improved biotin binding characteristics allows stable monovalent detection of biotinylated targets for imaging applications and can be recombinantly fused to introduce a biotin binding tag, report researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 1, 2016 Category: Science Source Type: news

Phosphopeptide Detection with Biotin-Labeled Phos-tag
Protein kinases are widely considered to be invaluable target enzymes for drug discovery and for diagnosing diseases and assessing their prognosis. Effective analytical techniques for measuring the activities of cellular protein kinases are therefore required for studies in the field of phosphoproteomics. We have recently developed a highly sensitive microarray-based technique for tracing the activities of protein kinases. A series of peptides that are specific substrates of various protein kinases are immobilized on a glass slide and subjected to phosphorylation by cell lysates. The resulting phosphorylated forms of the v...
Source: Springer protocols feed by Protein Science - November 19, 2015 Category: Biochemistry Source Type: news

MD1003 (Biotin) encouraging for progressive MS
A phase III trial shows evidence that MD1003 (Biotin) may be a safe and effective way of treating progressive MS. After a year on treatment, 1 in 6 of the treatment group showed a decrease of at least 0.5 on the EDSS measure of disability compared to none in the placebo group. The application process to license the drug is expected to begin by the end of the year. Presented at the American Academy of Neurology (AAN) meeting. Neurology Advisor MedPage Today Progressive forms of MS - A to Z of MS (Source: Multiple Sclerosis Trust)
Source: Multiple Sclerosis Trust - April 24, 2015 Category: Neurology Source Type: news

Biotin (MD1003) study
Pre-publicity for a presentation at AAN conference says that a study of the drug found it was associated with improvements in people with progressive MS. Results will be announced later in the week. MedPage Today MD1003 - Biotin - drugs in development (Source: Multiple Sclerosis Trust)
Source: Multiple Sclerosis Trust - April 17, 2015 Category: Neurology Source Type: news

The Strep-tag System for One-Step Affinity Purification of Proteins from Mammalian Cell Culture
The Strep-tag—or its improved version Strep-tagII—is an eight amino acid sequence that can be easily fused or conjugated to any protein or peptide of interest and that was engineered for high affinity toward streptavidin, which otherwise is widely known as a tight biotin-binding reagent. Especially in combination with immobilized Strep-Tactin, a mutant streptavidin specifically optimized toward the Strep-tagII, this system enables the facile one-step affinity purification of various biomolecules, including oligomeric and even membrane proteins. The Strep-tagII/Strep-Tactin interaction shows exquisite specificit...
Source: Springer protocols feed by Biochemistry - March 9, 2015 Category: Biochemistry Source Type: news

Cell Surface Biotinylation of Receptor Tyrosine Kinases to Investigate Intracellular Trafficking
Cell surface biotinylation is a biochemical approach to covalently bind membrane-impermeable biotin to the extracellular domain of membrane proteins, such as receptor tyrosine kinases (RTKs). Subsequent to ligand incubation periods, activated biotinylated receptors may internalize from the cell surface into early endosomes and then travel through intracellular compartments to either recycle back to the membrane or degrade in lysosomes. The biotin-labeled proteins may be detected through affinity purification with streptavidin agarose resins. This chapter describes methods for cell surface biotinylation to assess RTK traffi...
Source: Springer protocols feed by Protein Science - October 17, 2014 Category: Biochemistry Source Type: news