NEI Regenerative Medicine Clinical Trial Planning Grant (R34 - Clinical Trials Not Allowed)
Funding Opportunity PAR-22-135 from the NIH Guide for Grants and Contracts. The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some succe...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 8, 2022 Category: Research Source Type: funding

Age-related Macular Degeneration (AMD) Integrative Biology Initiative: Discovery of AMD Pathobiology using Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE) (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-EY-21-002 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) aims to support collaborative studies of a unique resource of patient-derived induced pluripotent stem cell (iPSC) lines generated by the NEI age-related macular degeneration (AMD) Integrative Biology Initiative. This resource also includes clinical, genomic, and imaging data from the patients from which these cells were derived, and a set of isogenic control cell lines in which the risk allele(s) have been corrected. These cell lines and clinical data are from patients with AMD carrying high preval...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 17, 2021 Category: Research Source Type: funding

NEI Regenerative Medicine Clinical Trial Planning Grant (R34 - Clinical Trials Not Allowed)
Funding Opportunity PAR-22-070 from the NIH Guide for Grants and Contracts. The National Eye Institute (NEI) Audacious Goal Initiative (AGI) is an effort to push the boundaries of vision science and restore vision through regeneration of cells in the retina. AGI research specifically targets photoreceptors (PRCs) and retinal ganglion cells (RGCs) in the eye. Photoreceptors often called rods and cones are cells in the retina that, when stimulated by light, generate signals the brain perceives as images. The retinal ganglion cells carry these signals from the photoreceptors to the brain. Although there has been some succe...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 16, 2021 Category: Research Source Type: funding

Delving Further into the Funding Gap Between White and Black Researchers
As is now well known, black scientists are less successful than their white counterparts in obtaining support from NIH R01 awards as designated Principal Investigators (PIs) (see here and here). Though recent NIH efforts are showing promise to enhance diversity in the biomedical workforce (see this post), much work is still needed to address the funding gap. In a paper recently published in Science Advances, we delved into the underlying factors associated with this funding gap. We identified three decision points where disparate outcomes arose between white and black researchers: 1) the decision to bring applications t...
Source: NIH Extramural Nexus - October 10, 2019 Category: Research Authors: Mike Lauer Tags: blog Open Mike application Diversity Funding data topic selection Source Type: funding

NEI Audacious Goals Initiative: Translation-Enabling Models to Evaluate Survival and Integration of Regenerated Neurons in the Visual System (U24 Clinical Trials Not Allowed)
Funding Opportunity RFA-EY-17-003 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to stimulate development of translation-enabling models for evaluating survival and integration of regenerated photoreceptors (PRCs) and retinal ganglion cells (RGCs) in model systems that are closer to human visual anatomy, function and/or disease than current models. The development of these models, tools, devices, novel therapies and/or other resources is expected to provide a resource to vision researchers developing cell-replacement therapies for visual system diseases and disorders. This FOA seeks to develop ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 7, 2017 Category: Research Source Type: funding