August 2021: Adulterant in Fentanyl Complicates OD
​A 38-year-old woman with opioid use disorder presented to the emergency department after an unintentional overdose. EMS said the patient was found with decreased respirations, and she was given 2 mg intranasal naloxone. She was awake, alert, and oriented x 3 in the emergency department.She reported that she used one bundle of fentanyl/heroin a day intravenously and that she had recently been hospitalized for four weeks for a wound infection. She stated that she used her usual dosage of fentanyl/heroin on discharge, not realizing how much her tolerance had decreased.She also said the fentanyl contained “tranq" (xy...
Source: The Tox Cave - August 2, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Biomaterial-Based Vaccine Against Bacterial Infection
Researchers at the Harvard Wyss Institute have developed a biomaterial-based vaccine technology that could provide prophylactic protection against bacterial infection and septic shock. The technology is delivered as a biomaterial scaffold. Once inside the body, it captures bacterial pathogens and then recruits and activates dendritic cells to initiate a broad immune response against the pathogen of choice. So far, the technology has demonstrated protective efficacy against sepsis in animals. Bacterial infections, once largely controllable with antibiotics, are becoming a growing problem with the rise of bacterial resist...
Source: Medgadget - July 12, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Materials Medicine Source Type: blogs

Ketamine ’s non-anesthetic powers: Please wait for the science
Ketamine (colloquially called“K,”“Special K,” or“Vitamin K”) is a potent, dissociative anesthetic. More specifically, it is a nonselective NMDA antagonist that initiates a wide array of physiological effects, already having ingratiated itself to a wider audience through its potential for abuse. Once used primarily in veterinary medicine, ketamine in recent years, however, hasRead more …Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 3, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/theodore-klug-md" rel="tag" > Theodore Klug, MD < /a > < /span > Tags: Meds Psychiatry Source Type: blogs

Suicide in veterinary medicine is a huge problem right now [PODCAST]
“I am a veterinarian. More specifically, I am a veterinary specialist, board-certified in emergency and critical care. I don ’t play with puppies and kittens. I treat the worst of the worst in a specialty hospital setting with a state-of-the-art ER and ICU. Despite years of education, including veterinary school, internship, fellowship, and residency to obtain […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 16, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Psychiatry Source Type: blogs

Suicide in veterinary medicine is a huge problem right now
I am a veterinarian.   More specifically, I am a veterinary specialist, board-certified in emergency and critical care.  I don’t play with puppies and kittens.  I treat the worst of the worst in a specialty hospital setting with a state-of-the-art ER and ICU.  Despite years of education, including veterinary schoo l, internship, fellowship, and residency to obtain […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 16, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/garret-pachtinger" rel="tag" > Garret Pachtinger, VMD < /a > < /span > Tags: Physician Psychiatry Source Type: blogs

Fight Aging! Newsletter, October 5th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 4, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Aging of Chimpanzees versus that of Humans
We humans are unusually long-lived in comparison to our near primate cousins, and also compared to other mammals of similar body mass. We also exhibit menopause, an end to reproductive capability well before the end of life, which occurs in only a small number of other mammalian species. With a few noteworthy exceptions, such as naked mole-rats, some bats, and we humans, mammalian lifespan correlates quite well with some combination of body mass and resting metabolic rate. So why are the outliers long-lived? Evolutionary theorists consider longer human life spans to be a consequence of our intelligence and culture. ...
Source: Fight Aging! - September 29, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Veterinary Vaccines
Laurel J. Gershwin and Amelia R. Woolums present a new book on Veterinary Vaccines: Current Innovations and Future Trends This concise book captures the essence of current and future shifts in vaccine development research that will likely transform our understanding of methods to stimulate specific and protective immune responses to infectious diseases, and to offer improved therapeutic applications for oncology patients. The book opens with a chapter on reverse vaccinology and systems vaccinology approaches that should lead to more effective vaccines with fewer side effects. This is followed by a chapter describing rece...
Source: Microbiology Blog: The weblog for microbiologists. - September 23, 2020 Category: Microbiology Source Type: blogs

Chlamydia book review
"... describe(s) new work that is underway in all aspects of chlamydiae biology, genetics and genomics, and host immune responses to chlamydiae ... The authors are noted experts on chlamydiae biology and genetics ... The chapters are well organized, flowing from epidemiology and clinical manifestations to biology, genetics and genomics, immunity, vaccines, interaction with the microbiome, and finally veterinary and animal models of chlamydia ... a current and comprehensive summary of Chlamydia research to clinicians and researchers alike." from Doodys read more ...Suggested reading: Chlamydia Biology: From Genome to Diseas...
Source: Microbiology Blog: The weblog for microbiologists. - September 22, 2020 Category: Microbiology Source Type: blogs

New insights on antibiotics use on crops amongst smallholder farmers
Philip Taylor and Robert Reeder, research scientists at CABI, did not start out looking for trends in antibiotic use in crops. In fact, both Drs. Taylor and Reeder’s primary interest at the start of their study was to simply understand the general use of agrochemicals and other agents by smallholder farmers in lower and middle income countries (LMIC).  What they found, however, as explained in their recently published article in CABI Agriculture and Bioscience, demonstrates how real-world data, drawn from community support networks, can unearth previously unknown uses of antibiotics which help protect the livelihoods of...
Source: BioMed Central Blog - August 10, 2020 Category: General Medicine Authors: Dylan Parker Tags: Biology Developing World Uncategorized agriculture AMR antimicrobial resistance Source Type: blogs

Vets Show “Weight Bias” Against Obese Dogs And Their Owners
By guest blogger Ananya Ak The concept of weight bias or “fatphobia”, the social stigma around obesity, has been around for quite a while. Studies have shown that such stigma is present even among medical professionals, which negatively impacts quality of care for patients with obesity. Over the years, there have been several instances of doctors attributing medical symptoms to obesity when the symptoms were actually caused by something more serious, like a tumour. But what about social stigma towards obese pets? Over 50% of cats and dogs in the USA are obese and, like humans, pets with obesity have a higher risk of me...
Source: BPS RESEARCH DIGEST - July 27, 2020 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Comparative guest blogger Health Source Type: blogs

Alphaherpesviruses
A new book on Alphaherpesviruses: Molecular Biology, Host Interactions and Control Since the last edition of this volume in 2011, our understanding of the alphaherpesviruses has significantly advanced creating the need for this new book that distils the most important new information to provide a timely overview. Chapters are written by well-respected researchers, each offering their perspectives on the current state of the field, using herpes simplex virus as the main focus. Topics covered include: genomics; entry into the cell; genome delivery from the cell periphery to the nucleus; the fate of the genome in the nucleus;...
Source: Microbiology Blog: The weblog for microbiologists. - July 17, 2020 Category: Microbiology Source Type: blogs

Health in 2 Point 00, Episode 131 | Tele-everything! Oscar, Evidation, Lululemon, Calibrate, & more
Today on Health in 2 Point 00, Jess and I talk about Oscar raising $225 million, Evidation Health raising $45 million doing digital clinical trials, Lululemon buying fitness startup Mirror for $500 million, Calibrate raising a $5.1 million seed round bringing telehealth to weight loss and metabolic health, at-home urine analysis startup Healthy.io buying Inui Health for $9 million, and Airvet raising $14 million for veterinary telemedicine. —Matthew Holt (Source: The Health Care Blog)
Source: The Health Care Blog - July 1, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health in 2 Point 00 Health Tech Health Technology Jessica DaMassa Matthew Holt Airvet Calibrate Evidation Health Healthy.io inui health Lululemon Mirror Oscar Telemedicine virtual care Source Type: blogs

Bacterial Viruses
Aidan Coffey and Colin Buttimer present a new book on Bacterial Viruses: Exploitation for Biocontrol and Therapeutics Written by internationally-recognised scientists involved in the exploitation of bacterial viruses in diverse areas from around the world, this book provides comprehensive coverage of the current research in several phage applications for biocontrol of undesirable bacteria in human and veterinary medicine, horticulture, aquaculture and food. Chapters from the famous centres of phage therapy in Wrocław and Tbilisi detail some of the pioneering historical contributions to the topic. The book also examine...
Source: Microbiology Blog: The weblog for microbiologists. - May 14, 2020 Category: Microbiology Source Type: blogs