A Retrospective Analysis of Intravenous Insulin versus Insulin and Nebulized Albuterol for the Treatment of Hyperkalemia in the Emergency Department
This article is protected by copyright. All rights reserved.PMID:38100157 | DOI:10.1002/jcph.2396 (Source: The Journal of Clinical Pharmacology)
Source: The Journal of Clinical Pharmacology - December 15, 2023 Category: Drugs & Pharmacology Authors: Sara N Roach Meghan L Fletcher Preeyaporn Sarangarm Source Type: research

A Retrospective Analysis of Intravenous Insulin versus Insulin and Nebulized Albuterol for the Treatment of Hyperkalemia in the Emergency Department
This article is protected by copyright. All rights reserved.PMID:38100157 | DOI:10.1002/jcph.2396 (Source: The Journal of Clinical Pharmacology)
Source: The Journal of Clinical Pharmacology - December 15, 2023 Category: Drugs & Pharmacology Authors: Sara N Roach Meghan L Fletcher Preeyaporn Sarangarm Source Type: research

A Retrospective Analysis of Intravenous Insulin versus Insulin and Nebulized Albuterol for the Treatment of Hyperkalemia in the Emergency Department
This article is protected by copyright. All rights reserved.PMID:38100157 | DOI:10.1002/jcph.2396 (Source: The Journal of Clinical Pharmacology)
Source: The Journal of Clinical Pharmacology - December 15, 2023 Category: Drugs & Pharmacology Authors: Sara N Roach Meghan L Fletcher Preeyaporn Sarangarm Source Type: research

Enzyme replacement therapy for late-onset Pompe disease
CONCLUSIONS: One trial compared the effect of ERT to placebo in LOPD, showing that alglucosidase alfa probably improves 6MWT and respiratory function (both moderate-certainty evidence). Avalglucosidase alfa probably improves 6MWT compared with alglucosidase alfa (moderate-certainty evidence). Cipaglucosidase plus miglustat probably improves FVC compared to alglucosidase alfa plus placebo (moderate-certainty evidence). Other trials studied the adjunct effect of clenbuterol and albuterol along with alglucosidase alfa, with little to no evidence of benefit. No significant rise in adverse events was noted with all ERTs. The im...
Source: Cochrane Database of Systematic Reviews - December 12, 2023 Category: General Medicine Authors: Sanjush Dalmia Reena Sharma Uma Ramaswami Derralynn Hughes Nikki Jahnke Duncan Cole Sherie Smith Tracey Remmington Source Type: research

Enzyme replacement therapy for late-onset Pompe disease
CONCLUSIONS: One trial compared the effect of ERT to placebo in LOPD, showing that alglucosidase alfa probably improves 6MWT and respiratory function (both moderate-certainty evidence). Avalglucosidase alfa probably improves 6MWT compared with alglucosidase alfa (moderate-certainty evidence). Cipaglucosidase plus miglustat probably improves FVC compared to alglucosidase alfa plus placebo (moderate-certainty evidence). Other trials studied the adjunct effect of clenbuterol and albuterol along with alglucosidase alfa, with little to no evidence of benefit. No significant rise in adverse events was noted with all ERTs. The im...
Source: Cochrane Database of Systematic Reviews - December 12, 2023 Category: General Medicine Authors: Sanjush Dalmia Reena Sharma Uma Ramaswami Derralynn Hughes Nikki Jahnke Duncan Cole Sherie Smith Tracey Remmington Source Type: research

An update on combination therapies for multiple sclerosis: where are we now?
Expert Rev Neurother. 2023 Dec 6:1-15. doi: 10.1080/14737175.2023.2289572. Online ahead of print.ABSTRACTINTRODUCTION: In theory, combination of two agents, which are suboptimal when given individually, may result in a significant increase in therapeutic effect. Combination therapies have proven particularly effective against infections such as HIV, cancer, and also chronic autoimmune diseases such as rheumatoid arthritis.AREAS COVERED: The authors review the literature, searching for randomized placebo-controlled or comparative, double-blind or investigator-blinded clinical trials, not including open label clinical trials...
Source: Expert Review of Neurotherapeutics - December 7, 2023 Category: Neurology Authors: Per Soelberg Sorensen Melinda Magyari Finn Sellebjerg Source Type: research