Vagus Nerve Stimulation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Investigation of non-invasive focused ultrasound efficacy on depressive-like behavior in hemiparkinsonian rats
Exp Brain Res. 2023 Dec 7. doi: 10.1007/s00221-023-06750-2. Online ahead of print.ABSTRACTDepression is a common non-motor symptom in Parkinson's disease (PD) that includes anhedonia and impacts quality of life but is not effectively treated with conventional antidepressants clinically. Vagus nerve stimulation improves treatment-resistant depression in the general population, but research about its antidepressant efficacy in PD is limited. Here, we administered peripheral non-invasive focused ultrasound to hemiparkinsonian ('PD') and non-parkinsonian (sham) rats to mimic vagus nerve stimulation and assessed its antidepress...
Source: Brain Research - December 7, 2023 Category: Neurology Authors: Rachael A Herlihy Francisco Alicandri Hudy Berger Huda Rehman Yifan Kao Kainat Akhtar Elizabeth Dybas Emily Mahoney-Rafferty Kassie Von Stein Raven Kirby Angela Tawfik Rachel Skumurski Paul J Feustel Eric S Molho Damian S Shin Source Type: research

Investigation of non-invasive focused ultrasound efficacy on depressive-like behavior in hemiparkinsonian rats
Exp Brain Res. 2023 Dec 7. doi: 10.1007/s00221-023-06750-2. Online ahead of print.ABSTRACTDepression is a common non-motor symptom in Parkinson's disease (PD) that includes anhedonia and impacts quality of life but is not effectively treated with conventional antidepressants clinically. Vagus nerve stimulation improves treatment-resistant depression in the general population, but research about its antidepressant efficacy in PD is limited. Here, we administered peripheral non-invasive focused ultrasound to hemiparkinsonian ('PD') and non-parkinsonian (sham) rats to mimic vagus nerve stimulation and assessed its antidepress...
Source: Experimental Brain Research - December 7, 2023 Category: Neuroscience Authors: Rachael A Herlihy Francisco Alicandri Hudy Berger Huda Rehman Yifan Kao Kainat Akhtar Elizabeth Dybas Emily Mahoney-Rafferty Kassie Von Stein Raven Kirby Angela Tawfik Rachel Skumurski Paul J Feustel Eric S Molho Damian S Shin Source Type: research

Vagus nerve stimulation as immunomodulatory therapy for stroke: A comprehensive review
Exp Neurol. 2023 Nov 30:114628. doi: 10.1016/j.expneurol.2023.114628. Online ahead of print.ABSTRACTStroke is a devastating cerebrovascular pathology with high morbidity and mortality. Inflammation plays a central role in the pathophysiology of stroke. Vagus nerve stimulation (VNS) is a promising immunomodulatory method that has shown positive effects in stroke treatment, including neuroprotection, anti-apoptosis, anti-inflammation, antioxidation, reduced infarct volume, improved neurological scores, and promotion of M2 microglial polarization. In this review, we summarize the current knowledge about the vagus nerve's immu...
Source: Experimental Neurology - December 2, 2023 Category: Neurology Authors: Matyas Jelinek Jolana Lipkova Kamil Duris Source Type: research

Vagus Nerve Stimulation in Ischemic Stroke
AbstractPurpose of ReviewVagus nerve stimulation (VNS) has emerged as a potential therapeutic approach for neurological and psychiatric disorders. In recent years, there has been increasing interest in VNS for treating ischemic stroke. This review discusses the evidence supporting VNS as a treatment option for ischemic stroke and elucidates its underlying mechanisms.Recent FindingsPreclinical studies investigating VNS in stroke models have shown reduced infarct volumes and improved neurological deficits. Additionally, VNS has been found to reduce reperfusion injury. VNS may promote neuroprotection by reducing inflammation,...
Source: Current Neurology and Neuroscience Reports - November 27, 2023 Category: Neuroscience Source Type: research

Clinical Perspective: EEG-Based Neuromodulation Technique for Epilepsy
Stud Health Technol Inform. 2023 Nov 23;308:590-596. doi: 10.3233/SHTI230889.ABSTRACTEpilepsy is the most common brain disorder around the world. The main treatments of epilepsy are through drug treatment or epilepsy surgery. However, examples of EEG-based neuromodulation treatments, such as Vagus nerve stimulation (VNS), thalamic deep brain stimulation (DBS), and responsive neuro-stimulation (RNS), are also promising therapeutic methods nowadays. The aim of the paper is to recognize the effectiveness and potential risks of the three techniques. By carrying out randomized multicenter double-blind trials, this research stud...
Source: Studies in Health Technology and Informatics - November 26, 2023 Category: Information Technology Authors: Zhengqiu Ge Source Type: research