Vagus Nerve Stimulation Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Self-administered non-invasive vagus nerve stimulation therapy for severe pharmacoresistant restless legs syndrome: outcomes at 6 months
J Sleep Res. 2023 Oct 17:e14066. doi: 10.1111/jsr.14066. Online ahead of print.ABSTRACTSevere pharmacoresistant restless legs syndrome (RLS) is difficult to manage and a source of suffering to patients. We studied the effectiveness at 6 months of an innovative treatment: transauricular vagus nerve stimulation (taVNS) in the left cymba concha in a case series of 15 patients, 53% male, mean (SD) age 62.7 (12.3) years with severe pharmacoresistant RLS (mean [SD] International Restless Legs Rating Scale [IRLS] score of 31.9 [2.9]) at baseline. Following an 8-week non-randomised hospital-based study with eight 1-h sessions of t...
Source: Journal of Sleep Research - October 17, 2023 Category: Sleep Medicine Authors: Sarah Hartley Guillaume Bao Ashley Russo Marine Zagdoun Sylvain Chevallier Fr édéric Lofaso Antoine Leotard Eric Azabou Source Type: research

Meniere Disease treated with transcutaneous auricular vagus nerve stimulation combined with betahistine Mesylate: A randomized controlled trial
Meniere Disease is a clinical condition defined by hearing loss, tinnitus, and aural fullness symptoms, there are currently no any medications approved for its treatment. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 12, 2023 Category: Neurology Authors: Dong Wu, Bo Liu, Yunqing Wu, Yu Wang, Jingyi Sun, Jun Yang, Jinping Duan, Gang Liu, Kai Cao, Yi Zhang, Peijing Rong Source Type: research

Vagus nerve stimulation and acetylcholinesterase inhibitor donepezil provide cardioprotection against trastuzumab-induced cardiotoxicity in rats by attenuating mitochondrial dysfunction
Biochem Pharmacol. 2023 Oct 8:115836. doi: 10.1016/j.bcp.2023.115836. Online ahead of print.ABSTRACTTrastuzumab (Trz) is a targeted anticancer drug for human epidermal growth factor receptor 2 (HER2)-positive tumors, as Trz-induced cardiotoxicity (TIC) is commonly observed in Trz-treated patients. Since cardiac autonomic modulation with electrical vagus nerve stimulation (VNS) and acetylcholinesterase (AChE) inhibitors exerts cardioprotection against various heart diseases, the comparative effects of electrical VNS and an AChE inhibitor (donepezil) on cardiac and mitochondrial functions and programmed cell death pathways i...
Source: Biochemical Pharmacology - October 10, 2023 Category: Drugs & Pharmacology Authors: Thawatchai Khuanjing Chayodom Maneechote Benjamin Ongnok Nanthip Prathumsap Apiwan Arinno Titikorn Chunchai Busarin Arunsak Siriporn C Chattipakorn Nipon Chattipakorn Source Type: research

Causal influence of brainstem response to transcutaneous vagus nerve stimulation on cardiovagal outflow
The autonomic response to transcutaneous auricular vagus nerve stimulation (taVNS) has been linked to the engagement of brainstem circuitry modulating autonomic outflow. However, the physiological mechanisms supporting such efferent vagal responses are not well understood, particularly in humans. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 10, 2023 Category: Neurology Authors: Nicola Toschi, Andrea Duggento, Riccardo Barbieri, Ronald G. Garcia, Harrison P. Fisher, Norman W. Kettner, Vitaly Napadow, Roberta Sclocco Source Type: research

Migraine and treatment-resistant depression
Prog Brain Res. 2023;281:149-173. doi: 10.1016/bs.pbr.2023.05.001. Epub 2023 Jun 23.ABSTRACTMigraine and major depressive disorders (MDD) or treatment resistant depression (TRD) represent a significant global burden and are often comorbid, further complicating diagnosis and treatment. Epidemiological studies have demonstrated a bidirectional relationship between migraine and MDD/TRD, with patients suffering from one disorder exhibiting a heightened risk of developing the other. This association is believed to result from shared genetic factors, neurotransmitter dysregulation, inflammation, hormonal alteration, and other co...
Source: Brain Research - October 8, 2023 Category: Neurology Authors: Shih-Pin Chen Source Type: research

Clinical Research Progress of the Post-Stroke Upper Limb Motor Function Improvement via Transcutaneous Auricular Vagus Nerve Stimulation
Neural Plast. 2023 Sep 25;2023:9532713. doi: 10.1155/2023/9532713. eCollection 2023.ABSTRACTStroke is a disease with high morbidity and disability, and motor impairment is a common sequela of stroke. Transcutaneous auricular vagus nerve stimulation (taVNS) is a type of non-invasive stimulation, which can effectively improve post-stroke motor dysfunction. This review discusses stimulation parameters, intervention timing, and the development of innovative devices for taVNS. We further summarize the application of taVNS in improving post-stroke upper limb motor function to further promote the clinical research and application...
Source: Neural Plasticity - October 4, 2023 Category: Neurology Authors: Xiaolong Shi Jingjun Zhao Shutian Xu Meng Ren Yuwei Wu Xixi Chen Zhiqing Zhou Songmei Chen Yu Huang Yuanli Li Chunlei Shan Source Type: research