Fight Aging! Newsletter, August 17th 2020
In this study, we sought to elucidate the role of VRK-1 in regulation of adult life span in C. elegans. We found that overexpression of VRK-1::GFP (green fluorescent protein), which was detected in the nuclei of cells in multiple somatic tissues, including the intestine, increased life span. Conversely, genetic inhibition of vrk-1 decreased life span. We further showed that vrk-1 was essential for the increased life span of mitochondrial respiratory mutants. We demonstrated that VRK-1 was responsible for increasing the level of active and phosphorylated form of AMPK, thus promoting longevity.
A Fisetin Variant, C...
Source: Fight Aging! - August 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
In the COVID-19 era, point of care ultrasound has proven invaluable
Amidst the crushing human and economic carnage inflicted by the COVID-19 pandemic, one innocent bystander has been cowering in the dark corner of medicine ’s past, clinging to its final breaths of iconicity: the beloved stethoscope. For over two centuries, there has been no better physician archetype than the quintessential rubber tube donned confidently over a […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 13, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/larry-istrail" rel="tag" > Larry Istrail, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Radiology Source Type: blogs
Considering the Use of Lasers to Break Down Harmful Protein Aggregates
It is possible to tailor the frequency of laser light to selectively disrupt the bonds or structure of particular arrangements of molecules - such as, say, the harmful protein aggregates found in neurodegenerative and other age-related conditions. Researchers here showcase early work into the disruption of amyloids, a class of altered of proteins that feature prominently in numerous conditions. The challenge in this sort of approach is usually not that of achieving the desired disruption, but rather doing so without the delivery of so much energy, released as heat, that the process kills surrounding cells and tissues. Past...
Source: Fight Aging! - August 12, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
PulseNmore At-Home Tele-Ultrasound for Pregnant Women
During these trying COVID days, patients have been limited in the care they receive because clinics have been limiting access and because patients themselves have been wary of visiting medical facilities. Pregnant women are a particularly vulnerable group and require frequent office visits, including receiving ultrasound exams.
A new device has just been unveiled by PulseNmore, an Israeli firm, that allows patients to perform ultrasound exams themselves and share the results immediately with their sonographers or physicians.
The device is a dock for a smartphone, the bottom being the ultrasound transducer. An a...
Source: Medgadget - August 10, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Ob/Gyn Public Health Radiology Telemedicine Source Type: blogs
Optical coherence tomography (OCT) – Cardiology MCQ – Answer
Optical coherence tomography (OCT) – Cardiology MCQ – Answer
Optical coherence tomography (OCT) compared to intravascular ultrasound (IVUS) has – Correct answer: 1. OCT has higher resolution but lower depth penetration
Optical coherence tomography (OCT) has much higher resolution compared to intravascular ultrasound. It has the resolution of the range of 10 – 20 microns, which is an order of magnitude better than that of intravascular ultrasound. But the limitation is the lower depth of tissue penetration which is only 2 to 3 millimeters, compared to the 10 millimeter tissue penetration of current i...
Source: Cardiophile MD - August 9, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
