Accelerating the Development of Tests for Endometriosis and Cancer
NIGMS’ Small Business Technology Transfer (STTR) program works toward more effective methods for patient screening, diagnosis, and treatment.
Translating lab discoveries into health care products requires large investments of time and resources. Through the STTR Regional Technology Transfer Accelerator Hubs for IDeA States program, NIGMS helps researchers interested in transitioning their discoveries and/or inventions into products. Here are the stories of three researchers working with the XLerator Hub, which funds projects in the southeastern United States and Puerto Rico.
Ending Diagnostic Delays for Endomet...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 7, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness Cancer Diseases Profiles Scientific Process Source Type: blogs
Paroxysmal Atrial Fibrillation with RVR, hypotension, volume depletion, good EF, AND pulmonary edema. Strange. Why? What to do?
A 30-something woman presented with a few days of feeling ill. She had a history of paroxysmal atrial fibrillation, bio-prosthetic mitral valve, and tricuspid valvuloplasty, and was on Coumadin.Records showed she is usually in sinus rhythm and has normal LV function.She presented hypotensive (systolic pressure 80), with diffuse B lines, flat IVC, good LV function, and an irregular, fast heart beat.Here is here ECG:Atrial fib with RVR and some probable ischemic ST depression in V3-V6Here is her POCUS:What do you think? There is asmall LV with good function and alarge left atrium, andmoderately large RV.Ther...
Source: Dr. Smith's ECG Blog - April 4, 2021 Category: Cardiology Authors: Steve Smith Source Type: blogs
A man in his 40s with a highly specific ECG
In conclusion, the presence of negative T waves in both leads III and V1 allows PE to be differentiated simply but accurately from ACS in patients with negative T waves in the precordial leads. "Witting et al. looked at consecutive patients with PE, ACS, or neither. They found that only 11% of PE had 1 mm T-wave inversions in both lead III and lead V1, vs. 4.6% of controls. This does not contradict the conclusions of Kosuge et al. that when T-wave inversions in the right precordial leads and in lead III are indeed present, then PE may indeed by more common. In m...
Source: Dr. Smith's ECG Blog - March 30, 2021 Category: Cardiology Authors: Pendell Source Type: blogs
Ultrasound Technology to Decode Brain Activity for Brain Machine Interfaces
Researchers at Caltech have developed a non-invasive functional ultrasound system that can detect brain activity by listening to tiny changes in blood flow within the brain. The system could provide a viable alternative to invasive electrodes that are implanted into the brain for brain machine interfaces, such as those used in prosthetics. So far, the system can detect the brain activity corresponding to a specific body movement in non-human primates, before the movement occurs.
Brain machine interfaces hold significant promise for those with paralysis in controlling a variety of assistive technologies, such as wheelcha...
Source: Medgadget - March 23, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Radiology Rehab Source Type: blogs
Nanoparticles On My Mind
By KIM BELLARD
Nanoparticles are everywhere! By that I mean, of course, that there seems to be a lot of news about them lately, particularly in regard to health and healthcare. But, of course, literally they could be anywhere and everywhere, which helps account for their potential, and their potential danger.
Let’s start with one of the more startling developments: a team at the University of Miami’s College of Engineering, led by Professor Sakhrat Khizroev, believes it has figured out a way to use nanoparticles to “talk” to the brain without wires or implants. They use “a novel clas...
Source: The Health Care Blog - March 23, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard nanoparticles Source Type: blogs
The Art of Clinical Decision Making: Friday Afternoon Dilemmas
By HANS DUVEFELT
The woman had a bleeding ulcer and required a blood transfusion. The hospital discharge summary said to see me in three days for a repeat CBC. But she had a late Friday appointment and there was no way we would get a result before the end of the day. She also had developed diarrhea on her pantoprazole and had stopped the medication. As if that wasn’t enough, her right lower leg was swollen and painful. She had been bed bound for a couple of days in the hospital and sedentary at home after discharge.
She could still be bleeding and she could have a blood clot. There were no openings for an ultrasoun...
Source: The Health Care Blog - March 22, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt Source Type: blogs
The Future Of Healthcare Design – Outside The Point Of Care
When talking about the future of healthcare, we also have to talk about the future designs of the institutions providing medical services. However, with digital health technologies that democratise access to care, the point of care will not be limited to healthcare institutions. It will rather be split into two; with hospitals becoming health centres for disease prevention, acute care and surgical needs, while monitoring patients’ vitals will be done closer to patients themselves.
We explore these aspects of the future of hospital design in this two-part series. In the first article, we looked at design adjustments to...
Source: The Medical Futurist - March 18, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Forecast Lifestyle medicine Digital Health Research E-Patients Future of Medicine Future of Pharma Health Sensors & Trackers Healthcare Design Portable Medical Diagnostics Robotics Security & Privacy Telemedicine & Smartphones ecg Source Type: blogs
One year into the COVID-19 pandemic
“Come to triage right now, and wear your N95. A patient going straight to OR and she’s having fever and chills.” I was summoned to the triage area of labor and delivery for a patient brought in from the ultrasound clinic and found to have absent fetal heart tones. One of my colleagues started an […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 15, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/maria-sheikh" rel="tag" > Maria Sheikh, MD, MPH < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs
80-something year old with acute chest pain. 3 visits. Fascinating Ultrasound progression
An 80-something year old man with history of metastatic cancer had acute onset of chest pain and called 911.Here is his prehospital ECG:What do you think?The computer read ***Anterior STEMI*** along with RBBB.Smith interpretation: There is Right Bundle Branch Block (RBBB). There is 1 mm of STE in inferior leads and also in lateral precordial leads. As a general rule, RBBB should not have ST Elevation (there are some infrequent patients with RBBB who have non-ischemic STE, usually discordant to the negative S-wave, as in this case). Moreover, the T-waves appear hyperacute.I would activate the cath lab base...
Source: Dr. Smith's ECG Blog - March 15, 2021 Category: Cardiology Authors: Steve Smith Source Type: blogs
Miniaturized Ultrasound Equipment Can Transform Healthcare, But Training Needs to Be Prioritized
The following is a guest article by Dale R. Cyr, CEO & Executive Director, Inteleos. Recent technological innovations have “miniaturized” ultrasound devices, and these hand-held devices are having a significant impact on healthcare around the world. And the market is growing. According to research firm Market Data forecast, the global portable ultrasound market was worth […] (Source: EMR and HIPAA)
Source: EMR and HIPAA - March 12, 2021 Category: Information Technology Authors: Guest Author Tags: Clinical Health IT Company Healthcare IT Dale R. Cyr Healthcare Devices Inteleos Medical Devices POCUS Ultrasound Ultrasound Training Source Type: blogs
March 2021: Injury Without Trauma
She was actively holding her arm against her side, her hand wrapping around her wrist. Any attempt to move her shoulder, actively or passively, brought an involuntary wince of pain. Tears quickly followed.My patient, a woman in her 40s, described increasing diffuse shoulder pain over two days. There was no trauma, but she described excruciating pain. She couldn't raise her arm at all, so I thought about a rotator cuff injury.She had had no injury, but rotator cuff tendons can give way to repetitive injury that thins the tissue until one day it just it breaks. It seemed more agony than this etiology would give. Maybe there ...
Source: Lions and Tigers and Bears - March 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Valvuloarterial impedance (Zva): Global left ventricular afterload in aortic stenosis
Valvuloarterial impedance (Zva) is an echocardiographic measure of global left ventricular afterload in aortic stenosis [1]. It accounts for the effect of both aortic stenosis and systemic arterial compliance.
Zva (mmHg/ml/m2) = (systolic blood pressure + mean transvalvular pressure gradient)/stroke volume index
Here the systemic arterial pressure and mean transvalvar gradient are taken beyond the region of pressure recovery in aortic stenosis. This mean transvalvar gradient has been called the net mean gradient.
In a study of 208 patients with at least moderate aortic stenosis, Briand M and colleagues found that...
Source: Cardiophile MD - February 26, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Echocardiography Aortic stenosis aortic stenosis with hypertension Global left ventricular afterload Global left ventricular afterload in aortic stenosis mean transvalvar gradient net mean gradient pressure recovery in aortic stenosis Valv Source Type: blogs
Clear Cranial Implant Allows Ultrasound Imaging of Brain: Interview with CEO of Longeviti Neuro Solutions
Longeviti Neuro Solutions, a medtech company based in Maryland, has announced that its ClearFit cranial implant has been cleared by the FDA for post-surgery ultrasound imaging. The clear implants are used for cranial reconstruction after brain surgery, and are custom-made for each patient. The company uses patient CT scans and 3D printing to produce the custom implants, and then sends the sterile constructs directly to surgeons.
Typically, ultrasound imaging of the brain is not possible in adults because of the properties of the skull. The implants allow clinicians to perform this task by being nearly transparent to ult...
Source: Medgadget - February 22, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurosurgery Orthopedic Surgery longeviti Source Type: blogs
What to do when Atrial Fib with RVR will not Electrically Cardiovert. And how do you measure the QT in Atrial Fib?
Conclusions.The efficacy of transthoracic cardioversion for converting atrial fibrillation to sinus rhythm was enhanced by pretreatment with ibutilide. However, use of this drug should be avoided in patients with very low ejection fractions. (N Engl J Med 1999;340:1849-54.) Important aspects to this study:They included patients who had had a fib for less than 48 hours.They excluded patients with a fib for longer than 48 hours unless they proved, by TE echo, to not have an atrial clot OR unless they anticoagulated them for 3 weeks first.Therefore, our patients who have been in afib< 48 hours, or who have been on ant...
Source: Dr. Smith's ECG Blog - February 12, 2021 Category: Cardiology Authors: Steve Smith Source Type: blogs
Ultrasound Can ‘Jump-Start’ Brain From Coma-Like State
After treatment, the two patients were able to understand language and communicate for the first time in years.
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Source: PsyBlog | Psychology Blog - February 9, 2021 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Neuroscience Source Type: blogs
