Labour Care Guide implementation as a decision-making tool for monitoring labour among healthcare providers in Uganda: protocol for a mixed-methods study
Introduction
The new WHO Labour Care Guide (LCG), also regarded as the ‘next-generation partograph’, is a core component of 2018 WHO consolidated guidelines on intrapartum care for positive childbirth experience. The Ugandan Ministry of Health is in the process of adopting the new WHO LCG with no local context-specific data to inform this transition. We will explore potential barriers and facilitators to healthcare providers’ (HCPs) sustained engagement in labour monitoring in Mbarara city, Southwestern Uganda, and use the data to refine the new WHO LCG and develop a suitable implementation strategy to ef...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Mugyenyi, G. R., Byamugisha, J., Tumuhimbise, W., Atukunda, E., Yarine, F. T. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
Corneal endothelial cell density and associated factors among adults at a regional referral hospital in Uganda: a cross-sectional study
To assess the prevalence of low corneal endothelial cell density and correlates of corneal endothelial cell density among adults attending Mbarara University and Referral Hospital Eye Centre in Uganda. (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - April 15, 2024 Category: Opthalmology Authors: Shamiim Namwase, Sam Ruvuma, John Onyango, Teddy Kwaga, Abel Ebong, Daniel Atwine, David Mukunya and Simon Arunga Tags: Research Source Type: research
Viruses, Vol. 16, Pages 599: Circulation of West Nile Virus and Usutu Virus in Europe: Overview and Challenges
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West Nile Virus (WNV) and Usutu Virus (USUV) are both neurotropic mosquito-borne viruses belonging to the Flaviviridae family. These closely related viruses mainly follow an enzootic cycle involving mosquitoes as vectors and birds as amplifying hosts, but humans and other mammals can also be infected through mosquito bites. WNV was first identified in Uganda in 1937 and has since spread globally, notably in Europe, causing periodic outbreaks associated with severe cases of neuroinvasive diseases such as meningitis and encephalitis. USUV was initially isolated in 1959 in Swaziland and has also spread to Europe, primar...
Source: Viruses - April 12, 2024 Category: Virology Authors: Yannick Simonin Tags: Perspective Source Type: research
Examining the Intrapersonal, Interpersonal and Community Level Correlates of Access to Medical Care Among Women Employed by Sex Work in Southern Uganda: A cross-sectional Analysis of the Kyaterekera Study
AbstractWomen employed by sex work (WESW) experience significant gaps in accessing necessary healthcare services, leading to unmet health needs. Yet, there is a dearth of literature on the barriers to medical care access among WESW in Uganda. We used data from the Kyaterekera baseline to examine the correlates of access to medical care among WESW, defined as the ability of individuals to obtain the necessary healthcare services they require in a timely, affordable, and equitable manner. The Kyaterekera study recruited 542 WESW aged 18 –58 years from Southern Uganda. We conducted a multilevel linear regression model to de...
Source: AIDS and Behavior - April 12, 2024 Category: Infectious Diseases Source Type: research
Prevalence and Correlates of Substance Use Among Youth Living with HIV in Fishing Communities in Uganda
AbstractAlcohol and drug use (ADU) poses a significant barrier to optimal HIV treatment outcomes for adolescents and youths living with HIV (AYLHIV). We aimed to investigate the prevalence and correlates of ADU among ALHIV in Ugandan fishing communities, areas characterized by high HIV and poverty rates. AYLHIV aged 18 –24, who knew they were HIV-positive, were selected from six HIV clinics. Substance use was determined through self-report in the last 12 months and urine tests for illicit substances. Utilizing a socioecological framework, the study structured variables into a hierarchical logistic regression ana lysis to...
Source: AIDS and Behavior - April 12, 2024 Category: Infectious Diseases Source Type: research
News at a glance: Jailed conservationists freed, physics titan dies, and diversity in anatomical illustrations
ASTRONOMY
Scientists flock to the eclipse
Tens of millions in North America turned their specially protected eyes to the skies on 8 April for several minutes of darkness when the Moon blocked the disk of the Sun, casting a shadow across Mexico, 15 U.S. states, and Canada. Researchers and citizen scientists seized the opportunity to study the corona—the wispy, outer layer of the Sun’s atmosphere—from the ground and in eclipse-chasing aircraft. They expected to see loops of plasma and other solar flares because the eclipse coincided with solar maximum, a period of high magnetic activity. Research...
Source: Science of Aging Knowledge Environment - April 11, 2024 Category: Geriatrics Source Type: research
A sophisticated virulence repertoire and colistin resistance of Citrobacter freundii ST150 from a patient with sepsis admitted to ICU in a tertiary care hospital in Uganda, East Africa: Insight from genomic and molecular docking analyses
Infect Genet Evol. 2024 Apr 9:105591. doi: 10.1016/j.meegid.2024.105591. Online ahead of print.ABSTRACTSepsis and multidrug resistance comprise a complex of factors attributable to mortality among intensive care unit (ICU) patients globally. Pathogens implicated in sepsis are diverse, and their virulence and drug resistance remain elusive. From a tertiary care hospital ICU in Uganda, we isolated a Citrobacter freundii strain RSM030 from a patient with sepsis and phenotypically tested it against a panel of 16 antibiotics including imipenem levofloxacin, cotrimoxazole and colistin, among others. We sequenced the organism's g...
Source: Infection, Genetics and Evolution - April 11, 2024 Category: Genetics & Stem Cells Authors: Reuben S Maghembe Maximilian A K Magulye Emmanuel Eilu Simon Sekyanzi Abdalah Makaranga Savannah Mwesigwa Eric Katagirya Source Type: research
A sophisticated virulence repertoire and colistin resistance of Citrobacter freundii ST150 from a patient with sepsis admitted to ICU in a tertiary care hospital in Uganda, East Africa: Insight from genomic and molecular docking analyses
Infect Genet Evol. 2024 Apr 9:105591. doi: 10.1016/j.meegid.2024.105591. Online ahead of print.ABSTRACTSepsis and multidrug resistance comprise a complex of factors attributable to mortality among intensive care unit (ICU) patients globally. Pathogens implicated in sepsis are diverse, and their virulence and drug resistance remain elusive. From a tertiary care hospital ICU in Uganda, we isolated a Citrobacter freundii strain RSM030 from a patient with sepsis and phenotypically tested it against a panel of 16 antibiotics including imipenem levofloxacin, cotrimoxazole and colistin, among others. We sequenced the organism's g...
Source: Infection, Genetics and Evolution - April 11, 2024 Category: Genetics & Stem Cells Authors: Reuben S Maghembe Maximilian A K Magulye Emmanuel Eilu Simon Sekyanzi Abdalah Makaranga Savannah Mwesigwa Eric Katagirya Source Type: research
Baseline knowledge on risk factors, symptoms and intended behavior of women and men towards screening and treatment of cervical cancer in rural Uganda: a cross-sectional study
Knowledge of risk factors and symptoms of cervical cancer has been found to promote uptake of screening of cervical cancer. Most interventions targeted women without much involvement of men (husbands/decision ... (Source: BMC Cancer)
Source: BMC Cancer - April 11, 2024 Category: Cancer & Oncology Authors: Carolyn Nakisige, Marlieke de Fouw, Miriam Nakalembe, Jackson Orem, Dan Atukonyera, Mwalimu Musheshe, Jaap Koot, Janine de Zeeuw, Jogchum Beltman and Jelle Stekelenburg Tags: Research Source Type: research
Willingness to receive COVID-19 vaccines, associated factors and reasons for not taking a vaccine: a cross sectional study among persons aged 13 –80 years in Wakiso, Central Uganda
Vaccination has been recommended as one of the approaches for the control of COVID-19 pandemic. However, adequate vaccine coverage is critical to the effectiveness of the vaccine at population level. Data on a... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 11, 2024 Category: Infectious Diseases Authors: Alex Daama, Naziru Rashid, Kasango Asani, Grace Kigozi Nalwoga, Fred Nalugoda, Robert Bulamba, Emmanuel Kyasanku, Gertrude Nakigozi, Godfrey Kigozi, Joseph Kagaayi and Stephen Mugamba Tags: Research Source Type: research
Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen
In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, soil transmitted helminths infection and filariasis, and the Ebola virus glycoprotein (EBOV GP) antibody concentration in response to vaccination with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen in African and European participants using samples obtained from three international clinical trials. Methods/Principal findingsWe conducted a study in a subset of participants in the EBL2001, EBL2002 and EBL3001 clinical trials that evaluated the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen against EV...
Source: PLoS Neglected Tropical Diseases - April 11, 2024 Category: Tropical Medicine Authors: Houreratou Barry Source Type: research
Health-related quality of life among adult patients with cancer in Uganda - a cross-sectional study
CONCLUSION: Improvement of cancer care in East Africa requires a comprehensive and integrated approach that addresses various challenges specific to the region. Such strategies include investment in healthcare infrastructure, for example, clinical guidelines to improve pain management, and patient education and support services.PMID:38596846 | DOI:10.1080/16549716.2024.2325728 (Source: Global Health Action)
Source: Global Health Action - April 10, 2024 Category: International Medicine & Public Health Authors: Allen Naamala Lars E Eriksson Jackson Orem Gorrette K Nalwadda Zarina Nahar Kabir Lena Wettergren Source Type: research
Prevalence and Risk Factors for Newborn Anemia in Southwestern Uganda: A Cross-Sectional Study
CONCLUSIONS: We found a significant association between maternal and newborn hemoglobin, underscoring the importance of preventing and correcting maternal anemia in pregnancy. Furthermore, maternal anemia should be considered a risk factor for neonatal anemia.PMID:38596653 | PMC:PMC11003795 | DOI:10.1155/2024/5320330 (Source: Anemia)
Source: Anemia - April 10, 2024 Category: Hematology Authors: Joseph Ngonzi Leevan Tibaijuka Timothy Mwanje Kintu Raymond Bernard Kihumuro Onesmus Ahabwe Onesmus Byamukama Wasswa Salongo Julian Adong Adeline A Boatin Lisa M Bebell Source Type: research
Health-related quality of life among adult patients with cancer in Uganda - a cross-sectional study
CONCLUSION: Improvement of cancer care in East Africa requires a comprehensive and integrated approach that addresses various challenges specific to the region. Such strategies include investment in healthcare infrastructure, for example, clinical guidelines to improve pain management, and patient education and support services.PMID:38596846 | DOI:10.1080/16549716.2024.2325728 (Source: Global Health Action)
Source: Global Health Action - April 10, 2024 Category: International Medicine & Public Health Authors: Allen Naamala Lars E Eriksson Jackson Orem Gorrette K Nalwadda Zarina Nahar Kabir Lena Wettergren Source Type: research
Prevalence and Risk Factors for Newborn Anemia in Southwestern Uganda: A Cross-Sectional Study
CONCLUSIONS: We found a significant association between maternal and newborn hemoglobin, underscoring the importance of preventing and correcting maternal anemia in pregnancy. Furthermore, maternal anemia should be considered a risk factor for neonatal anemia.PMID:38596653 | PMC:PMC11003795 | DOI:10.1155/2024/5320330 (Source: Anemia)
Source: Anemia - April 10, 2024 Category: Hematology Authors: Joseph Ngonzi Leevan Tibaijuka Timothy Mwanje Kintu Raymond Bernard Kihumuro Onesmus Ahabwe Onesmus Byamukama Wasswa Salongo Julian Adong Adeline A Boatin Lisa M Bebell Source Type: research
