PRACTECAL-PKPD: Sub-study for TB-PRACTECAL Clinical Trial
Conditions:   Multi-drug Resistant Tuberculosis;   Extensively Drug-Resistant Tuberculosis;   Pulmonary Tuberculosis Interventions:   Drug: Bedaquiline;   Drug: Pretomanid;   Drug: Moxifloxacin;   Drug: Linezolid;   Drug: Clofazimine Sponsors:   Medecins Sans Frontieres, Netherlands;   London School of Hygiene and Tropical Medicine;   Global Alliance for TB Drug Development;   University College, London;   Drugs for Negle...
Source: ClinicalTrials.gov - September 9, 2019 Category: Research Source Type: clinical trials

PRACTECAL-PKPD Sub Study
Conditions:   Multi-drug Resistant Tuberculosis;   Extensively Drug-Resistant Tuberculosis;   Pulmonary Tuberculosis Interventions:   Drug: Bedaquiline;   Drug: Pretomanid;   Drug: Moxifloxacin;   Drug: Linezolid;   Drug: Clofazimine Sponsors:   Medecins Sans Frontieres, Netherlands;   London School of Hygiene and Tropical Medicine;   Global Alliance for TB Drug Development;   University College, London;   Drugs for Negle...
Source: ClinicalTrials.gov - September 9, 2019 Category: Research Source Type: clinical trials

Microbiome in Pulmonary Tuberculosis, Non-tuberculous Mycobacterial Pulmonary Diseases, Lung Cancer and Hemoptysis
Conditions:   Tuberculosis, Pulmonary;   Non-Tuberculous Mycobacterial Pneumonia;   Lung Cancer;   Hemoptysis Intervention:   Sponsor:   Gachon University Gil Medical Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2019 Category: Research Source Type: clinical trials

Evaluation of CRISPR-based Test for the Rapid Identification of TB in Pulmonary Tuberculosis Suspects
Condition:   Tuberculosis, Pulmonary Intervention:   Diagnostic Test: CRISPR-based Test Sponsors:   Huashan Hospital;   Wenzhou Central Hospital;   Hangzhou Red Cross Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 30, 2019 Category: Research Source Type: clinical trials

Addressing challenges in tuberculosis adherence via performance-based payments for integrated case management: protocol for a cluster randomized controlled trial in Georgia
DiscussionThe trial contributes to a limited body of rigorous evidence and literature on the effectiveness of supply-side performance-based financing interventions on tuberculosis patient outcomes. Realist and health economic evaluations will be conducted in parallel with the trial, and associated composite findings will serve as a resource for the Georgian and wider regional Ministries of Health in relation to future tuberculosis and wider health policies.The trial and complementing evaluations are part of Results4TB, a multidisciplinary collaboration engaging researchers and Georgian policy and practice stakeholders in t...
Source: Trials - August 28, 2019 Category: Research Source Type: clinical trials

Clinical Study to Evaluate Safety and Immunogenicity of Bacillus Calmette-Guerin (BCG) Delivery Via Novel Micronjet600 Device Compared to Those Via Conventional Needle
Conditions:   Tuberculosis;   BCG Vaccination Interventions:   Device: BCG vaccination with MicronJet600;   Device: BCG vaccination with conventional needle Sponsor:   Yonsei University Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 22, 2019 Category: Research Source Type: clinical trials