Community intervention for child tuberculosis active contact investigation and management: study protocol for a parallel cluster randomized controlled trial
This study aims to evaluate the impact of a community-based intervention as compared to facility-based model for the management of children in contact with bacteriologically confirmed pulmonary TB adults in low-resource high-burden settings.Methods/designThis multicenter parallel open-label cluster randomized controlled trial is composed of three phases: I, baseline phase in which retrospective data are collected, quality of data recording in facility registers is checked, and expected acceptability and feasibility of the intervention is assessed; II, intervention phase with enrolment of index cases and contact cases in ei...
Source: Trials - March 2, 2021 Category: Research Source Type: clinical trials

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis
Condition:   Tuberculosis Intervention:   Drug: Rifampin Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   University Medical Center Groningen;   Radboud University;   Centro Hospitalar De São João, E.P.E.;   Instituto Nacional de Enfermedades Respiratorias y del Ambiente, Paraguay Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 24, 2021 Category: Research Source Type: clinical trials

A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2
Condition:   Tuberculosis, Pulmonary Intervention:   Drug: Interleukin-2 Sponsor:   Beijing Chest Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2021 Category: Research Source Type: clinical trials

Evaluation of a Rapid Point-of-Care Serological Triage Test for Active TB
Condition:   Tuberculosis, Pulmonary Intervention:   Diagnostic Test: SeroSeelctTB rapid TB test Sponsors:   Norwegian Institute of Public Health;   European and Developing Countries Clinical Trials Partnership (EDCTP);   University of Stellenbosch;   Kilimanjaro Christian Medical University College;   Armauer Hansen Research Institute, Ethiopia;   Lateral Flow Laboratories (Pty)  Ltd;   National Institute for Public Health and the Environment (RIVM);   In...
Source: ClinicalTrials.gov - February 12, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Condition:   Tuberculosis Interventions:   Other: eTB Catalogue of Recommendations (eTB);   Other: World Health Organization Tuberculosis Website (WHO TB) Sponsors:   McMaster University;   World Health Organization Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB
Conditions:   Tuberculosis;   Hiv Intervention:   Drug: Dolutegravir 50 MG Sponsors:   University of KwaZulu;   Centre for the AIDS Programme of Research in South Africa Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2021 Category: Research Source Type: clinical trials