Microneedles for Diagnosis of LTBI
Condition:   Latent Tuberculosis Intervention:   Diagnostic Test: TST vs PPD microneedle test Sponsors:   The HIV Netherlands Australia Thailand Research Collaboration;   National Nanotechnology Center (NANOTEC), The National Science and Technology Development Agency (NSTDA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 17, 2020 Category: Research Source Type: clinical trials

Using BCG vaccine to enhance non-specific protection of health care workers during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial in Denmark
AbstractObjectives: The Bacille Calmette-Gu érin (BCG) vaccine against tuberculosis is associated with non- specific protective effects against other infections, and significant reductions in all-cause morbidity and mortality have been reported. We aim to test whether BCG vaccination may reduce susceptibility to and/or the severity of COVID- 19 and other infectious diseases in health care workers (HCW) and thus prevent work absenteeism.The primary objective is to reduce absenteeism due to illness among HCW during the COVID-19 pandemic. The secondary objectives are to reduce the number of HCW that are infected with S...
Source: Trials - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Conditions:   Tuberculosis;   Hiv Interventions:   Drug: Rifapentine daily;   Drug: Rifapentine weekly Sponsors:   Yale University;   Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Conditions:   Tuberculosis;   Hiv Interventions:   Drug: Rifapentine daily;   Drug: Rifapentine weekly Sponsors:   Yale University;   Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Conditions:   Tuberculosis;   Hiv Interventions:   Drug: Rifapentine daily;   Drug: Rifapentine weekly Sponsors:   Yale University;   Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Conditions:   Tuberculosis;   Hiv Interventions:   Drug: Rifapentine daily;   Drug: Rifapentine weekly Sponsors:   Yale University;   Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Conditions:   Tuberculosis;   Hiv Interventions:   Drug: Rifapentine daily;   Drug: Rifapentine weekly Sponsors:   Yale University;   Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Conditions:   Infections and Infestations;   Pulmonary Tuberculosis Interventions:   Drug: Delpazolid;   Drug: Bedaquiline, Delamanid, Moxifloxacin Sponsors:   LegoChem Biosciences, Inc;   Ludwig-Maximilians - University of Munich;   Radboud University;   University of California, San Francisco Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 16, 2020 Category: Research Source Type: clinical trials

Influence of Filarial Infections on Tuberculosis Disease and Tuberculosis Vaccination in Cameroon
Condition:   Tuberculosis Intervention:   Drug: TB treatment according to national guidelines Sponsor:   University Hospital, Bonn Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 14, 2020 Category: Research Source Type: clinical trials

Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis
Condition:   Tuberculosis Intervention:   Drug: Total oral short-term therapy that includes linezolid, bedaquiline and/or cycloserine. Sponsor:   Beijing Chest Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 11, 2020 Category: Research Source Type: clinical trials

Computer Aided Screening for Tuberculosis in Low Resource Environments
Conditions:   Tuberculosis Infection;   HIV Infections Interventions:   Diagnostic Test: CAD4TB;   Diagnostic Test: FujiLAM Sponsors:   London School of Hygiene and Tropical Medicine;   Liverpool School of Tropical Medicine;   University of Malawi College of Medicine;   Malawi-Liverpool-Wellcome Trust Clinical Research Programme Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 10, 2020 Category: Research Source Type: clinical trials