New Reusable Mask Design With Superior Filtration and Fit
Conditions:   Covid19;   Tuberculosis;   Respiratory Viral Infection Interventions:   Device: N95 mask;   Device: Nordell single E-100 layer mask;   Device: Nordell double E-100 layer mask Sponsor:   Mayo Clinic Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2021 Category: Research Source Type: clinical trials

Lipoarabinomannan (LAM) in Urine for Diagnosis of Pulmonary Tuberculosis in HIV Patients
Condition:   Role of Urinary LAM in Diagnosis of Active Tuberculosis in Patients With HIV Intervention:   Diagnostic Test: Urinary LAM ELISA: Sponsor:   Mansoura University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 24, 2021 Category: Research Source Type: clinical trials

Lipoarabinomannan (LAM) in Urine for Diagnosis of Pulmonary Tuberculosis in HIV Patients
Condition:   TB - Tuberculosis HIV Intervention:   Diagnostic Test: Urinary LAM ELISA: Sponsor:   Mansoura University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 24, 2021 Category: Research Source Type: clinical trials

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis
Conditions:   Tuberculosis, Pulmonary;   Tuberculosis, Multidrug-Resistant;   Bacterial Infections;   Mycobacterial Infection Intervention:   Diagnostic Test: Individualised treatment duration based on RNA transcriptomic model Sponsors:   Research Center Borstel;   Ludwig-Maximilians - University of Munich Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2021 Category: Research Source Type: clinical trials

Early Risk Assessment in Household Contacts ( ≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
Condition:   Tuberculosis Intervention:   Diagnostic Test: New test candidates Sponsors:   Michael Hoelscher;   European and Developing Countries Clinical Trials Partnership (EDCTP) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2021 Category: Research Source Type: clinical trials

Early Risk Assessment in Household Contacts ( ≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
Condition:   Tuberculosis Intervention:   Diagnostic Test: New test candidates Sponsors:   Michael Hoelscher;   European and Developing Countries Clinical Trials Partnership (EDCTP) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2021 Category: Research Source Type: clinical trials

Early Risk Assessment in Household Contacts ( ≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
Condition:   Tuberculosis Intervention:   Diagnostic Test: New test candidates Sponsors:   Michael Hoelscher;   European and Developing Countries Clinical Trials Partnership (EDCTP) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2021 Category: Research Source Type: clinical trials

Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers
Condition:   Tuberculosis Intervention:   Biological: BCG Danish Sponsor:   University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 2, 2021 Category: Research Source Type: clinical trials

Community intervention for child tuberculosis active contact investigation and management: study protocol for a parallel cluster randomized controlled trial
This study aims to evaluate the impact of a community-based intervention as compared to facility-based model for the management of children in contact with bacteriologically confirmed pulmonary TB adults in low-resource high-burden settings.Methods/designThis multicenter parallel open-label cluster randomized controlled trial is composed of three phases: I, baseline phase in which retrospective data are collected, quality of data recording in facility registers is checked, and expected acceptability and feasibility of the intervention is assessed; II, intervention phase with enrolment of index cases and contact cases in ei...
Source: Trials - March 2, 2021 Category: Research Source Type: clinical trials

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis
Condition:   Tuberculosis Intervention:   Drug: Rifampin Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   University Medical Center Groningen;   Radboud University;   Centro Hospitalar De São João, E.P.E.;   Instituto Nacional de Enfermedades Respiratorias y del Ambiente, Paraguay Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 24, 2021 Category: Research Source Type: clinical trials

A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2
Condition:   Tuberculosis, Pulmonary Intervention:   Drug: Interleukin-2 Sponsor:   Beijing Chest Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2021 Category: Research Source Type: clinical trials