Choosing An Antibiotic For Skin Infections--What's Best?
A new study in the New England Journal of Medicine on treatment of skin infections compares treatment with trimethoprim sulfamethoxazole (TMP-SMX, Bactrim or Septra) or clindamycin. Surprisingly, both worked equally well in this 524 patient study, curing about 89% of outpatients with uncomplicated skin infections cellulitis and abscesses, so the authors appear to encourage use of one of these drugs because they are better at treating MRSA than are currently recommended antibiotics. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 18, 2015 Category: Pharmaceuticals Authors: Judy Stone Source Type: news

Clindamycin, TMP-SMX are equally effective for skin infections
Clindamycin and trimethoprim-sulfamethoxazole are similarly safe and effective for treating uncomplicated skin infections, including both cellulitis and abscesses, in ambulatory settings in regions where MRSA is endemic, according to a report published online March 19 in the New England Journal of... (Source: Skin and Allergy News)
Source: Skin and Allergy News - March 18, 2015 Category: Dermatology Tags: CME-candidate EM Journals EM Clinical News EM News EM Dermatology EM Infectious Disease FPN Journals FPN News Source Type: news

Two commonly used antibiotics have similar cure rates for uncomplicated skin infections
(Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)) Two antibiotics frequently prescribed to treat serious skin infections -- clindamycin and trimethoprim sulfamethoxazole (TMP-SMX) -- had similar rates of success in curing uncomplicated infections in outpatients. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 18, 2015 Category: Infectious Diseases Source Type: news

Antibiotic, Spironolactone Combo Ups Sudden Death in Elderly Antibiotic, Spironolactone Combo Ups Sudden Death in Elderly
When combined with spironolactone, a diuretic, trimethoprim-sulfamethoxazole is riskier than other antibiotics in people older than 65 years. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 3, 2015 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

Commonly used antibiotics with diuretic can double risk of sudden death in older patients
The combination of the commonly prescribed antibiotic trimethoprim-sulfamethoxazole with the diuretic spironolactone, widely used for heart failure, more than doubles the risk of death for older patients, reports a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 2, 2015 Category: Science Source Type: news

Certain Heart Drug, Antibiotic Combo Might Be Fatal for Seniors
Doctors should not prescribe spironolactone with trimethoprim-sulfamethoxazole, study saysSource: HealthDay Related MedlinePlus Pages: Drug Reactions, Medicines, Seniors' Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 2, 2015 Category: Consumer Health News Source Type: news

trimethoprim, Trimpex (Discontinued Brand), Proloprim (Discontinued Brand), Primsol
Title: trimethoprim, Trimpex (Discontinued Brand), Proloprim (Discontinued Brand), PrimsolCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 1/28/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - January 28, 2015 Category: Drugs & Pharmacology Source Type: news

Concomitant Use of TMP-SMX and Common BP Drugs Linked to Sudden Death (FREE)
By Amy Orciari Herman Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Among older patients taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), concomitant use of the antibiotic trimethoprim-sulfamethoxazole is associated with increased risk for sudden death, … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 31, 2014 Category: Primary Care Source Type: news

polymyxin B sulfate and trimethoprim (Polytrim)
Title: polymyxin B sulfate and trimethoprim (Polytrim)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 10/24/2014 12:00:00 AM (Source: MedicineNet Eyesight General)
Source: MedicineNet Eyesight General - October 24, 2014 Category: Opthalmology Source Type: news

Antibiotic treatments 'fail' 15% of the time
ConclusionOverall, this is a highly informative study of GP antibiotic prescribing for common infections in the UK. The overall antibiotic treatment failure rate was 15% over the course of the study period; these were mainly cases where there was a need to prescribe a different antibiotic within 30 days. There was a slight increase in failure rate, from 13.9% in 1991 to 15.4% in 2012. Within the infection classes, particular antibiotics had notable changes in failure rates, while others remained fairly stable. Reassuringly, amoxicillin and other commonly prescribed antibiotics currently still have fairly low failure rates....
Source: NHS News Feed - September 26, 2014 Category: Consumer Health News Tags: Medication Medical practice Source Type: news

Steep rise in antibiotic use for coughs and colds
ConclusionThis cross-sectional study has found the proportion of people with coughs and colds that are prescribed antibiotics rose from 36% in 1999 to 51% in 2011 – an increase of approximately 40%. This is despite the publication of guidance recommending that GPs do not prescribe antibiotics for coughs and colds. It also found substantial variation between different GP practices, with 10% of practices prescribing antibiotics for less than 32% of cases and 10% of practices prescribing antibiotics for more than 65% of cases, suggesting that substantially lower rates of prescribing could be achieved.The study also looke...
Source: NHS News Feed - August 5, 2014 Category: Consumer Health News Tags: Medical practice Medication Source Type: news

What Medications Should Be Avoided with Long QT Syndrome?
Discussion Mycoplasma pneumoniae is a frequent cause of pharyngitis, pneumonia and acute bronchitis, but acute otitis media is uncommon. Symptoms are usually self-limited and variable and include cough (non-productive usually but later can be productive), fever, fatigue and occasionally headache. Coryza is rare. Cough can continue for 3 to 4 weeks and can be accompanied by wheezing. Radiographic changes include diffuse infiltrates or focal abnormalities but are variable. Long QT syndrome (LQTS) is a group of disorders that have a prolonged QT interval and a polymorphic ventricular tachycardia. Torsade de pointes (“t...
Source: PediatricEducation.org - July 14, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Global Trimethoprim Sulfate Industry Examined by 9Dimen Research in...
In-demand research study, “2014 Market Research Report on Global Trimethoprim Sulfate Industry,” worked out by 9Dimen Research is now available at MarketPublishers.com.(PRWeb July 01, 2014)Read the full story at http://www.prweb.com/releases/2014/07/prweb11985992.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 1, 2014 Category: Pharmaceuticals Source Type: news

Abandoned antibiotic makes a comeback
Scarlet fever and infections of the skin and throat are often caused by a bacterium called Streptococcus pyogenes. In less-developed countries, inexpensive and well-tolerated antibiotics for therapy are often not available. Scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, have discovered that trimethoprim may provide an option. Contrary to a long-held belief, the bacteria are not generally resistant to this agent. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 21, 2014 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Comeback of an abandoned antibiotic: Trimethoprim
In less-developed countries, inexpensive and well-tolerated antibiotics for therapy of streptococcal infections are often not available. Scientists have discovered that trimethoprim may provide an option. Contrary to a long-held belief, the bacteria are not generally resistant to this agent. In their latest publication the scientists demonstrated three pathways for the development of resistance -- meaning that streptococci can easily become resistant to the antibiotic and pass on this trait quickly. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 19, 2014 Category: Science Source Type: news