Interventions for the eradication of meticillinresistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
This review concluded that whilst early eradication of respiratory MRSA in cystic fibrosis with oral trimethoprim and sulfamethoxazole combined with rifampicin is possible, the evidence is of low quality to justify use. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 28, 2018 Category: Consumer Health News Source Type: news

Polytrim (Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution, USP, Sterile) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 6, 2018 Category: Drugs & Pharmacology Source Type: news

Deadly Respiratory Distress Mimic
Conclusion It’s important for prehospital providers to be able to differentiate metabolic disturbances in the setting of respiratory distress and not be fooled into thinking tachypnea always has a respiratory cause. The physical exam and adjuncts such as end-tidal capnography can assist in the prehospital diagnosis. A COPD exacerbation generally presents as diminished lung sounds, wheezing on exhalation, and a prolonged expiratory phase. Here, a patient will attempt to compensate for the inflammation and mucus accumulation associated with the destruction and narrowing of peripheral airways and a subsequent lack of availa...
Source: JEMS Special Topics - July 17, 2018 Category: Emergency Medicine Authors: Brenton Faber, PhD, NRP Tags: Airway & Respiratory Exclusive Articles Patient Care Source Type: news

Deadly Respiratory Distress Mimic
Medic 534, staffed by a paramedic and EMT, is dispatched to a nursing home for a 78-year-old female in respiratory distress. On arrival, the crew finds the patient in a chair accompanied by two nurses and the administrator on call. The patient is in obvious distress showing fatigue and an increased work of breathing. She is alert to voice, but diaphoretic, lethargic, and unable to speak due to rapid, shallow breathing. A nurse is administering a nebulizer containing 3 mL of albuterol sulfate/ipratropium. A second nurse states that the patient has been in increasing distress for the last 45 minutes. The nurse also says that...
Source: JEMS Patient Care - July 17, 2018 Category: Emergency Medicine Authors: Brenton Faber, PhD, NRP Tags: Airway & Respiratory Patient Care Source Type: news

Watch for Infections in Rituximab-Treated Vasculitis
(MedPage Today) -- Prophylaxis with trimethoprim-sulfamethoxazole lowered the risk by half (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 29, 2018 Category: Primary Care Source Type: news

Pregnant Women Getting UTI Meds Linked to Defects
The antibiotics -- trimethoprim-sulfamethoxazole (Bactrim) and nitrofurantoin (Macrobid) -- have been linked to a small risk for birth defects in pregnant women when given in the first trimester. (Source: WebMD Health)
Source: WebMD Health - January 12, 2018 Category: Consumer Health News Source Type: news

Pregnant Women Still Getting UTI Meds Linked to Birth Defects
FRIDAY, Jan. 12, 2018 -- Urinary tract infections (UTIs) can be problematic for pregnant women and their babies, but so can two antibiotics used to treat these infections, U.S. health officials warn. The antibiotics -- trimethoprim-sulfamethoxazole... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 12, 2018 Category: General Medicine Source Type: news

Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis
Cephalexin plus trimethoprim-sulfamethoxazole yielded no better clinical cure rates than cephalexin monotherapy, a new study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 24, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM For patients with uncomplicated cellulitis, adding trimethoprim-sulfamethoxazole (TMP/SMX) to cephalexin may offer no benefit beyond cephalexin alone, a JAMA study finds.Some 500 patients older than 12 years seen in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Stress may protect, at least in bacteria
Antibiotics harm bacteria and stress them. Trimethoprim, an antibiotic, inhibits the growth of the bacterium Escherichia coli and induces a stress response. This response also protects the bacterium from subsequent deadly damage from acid. Antibiotics can therefore increase the survival chances of bacteria under certain conditions. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 23, 2017 Category: Science Source Type: news

Stress may protect -- at least in bacteria
(Institute of Science and Technology Austria) Antibiotics harm bacteria and stress them. Trimethoprim, an antibiotic, inhibits the growth of the bacterium Escherichia coli and induces a stress response. This response also protects the bacterium from subsequent deadly damage from acid. Antibiotics can therefore increase the survival chances of bacteria under certain conditions. This is shown in a study by researchers at IST Austria (Karin Mitosch, Georg Rieckh and Tobias Bollenbach), which was published in the journal Cell Systems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2017 Category: Global & Universal Source Type: news

Relapses Common with S. Aureus Nasal Carriage in ANCA-Related Vasculitis (CME/CE)
(MedPage Today) -- Trimethoprim/sulfamethoxazole prophylaxis had no influence on relapse rate (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 6, 2017 Category: Rheumatology Source Type: news

Sulfatrim (Sulfamethoxazole and Trimethoprim Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 1, 2017 Category: Drugs & Pharmacology Source Type: news

Bactrim (Trimethoprim and Sulfamethoxazole) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Trimethoprim (Trimethoprim Tablet) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news