AvKARE Issues Voluntary Nationwide Recall of Sildenafil 100mg Tablets and Trazodone 100mg Tablets Due to Product Mix-Up
AvKARE, Pulaski, TN is voluntarily recalling one lot of Sildenafil 100 mg tablets and one lot of Trazodone 100mg tablets to the consumer level. These products have been recalled due to a product mix-up of the listed two separate products inadvertently packaged together during bottling at a 3rd party (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 9, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Trazodone (Desyrel)
Title: Trazodone (Desyrel)Category: MedicationsCreated: 3/26/1998 12:00:00 AMLast Editorial Review: 2/12/2020 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 12, 2020 Category: Psychiatry Source Type: news
Signaling from mTOR to eIF2{alpha} mediates cell migration in response to the chemotherapeutic doxorubicin
After exposure to cytotoxic chemotherapeutics, tumor cells alter their translatome to promote cell survival programs through the regulation of eukaryotic initiation factor 4F (eIF4F) and ternary complex. Compounds that block mTOR signaling and eIF4F complex formation, such as rapamycin and its analogs, have been used in combination therapies to enhance cell killing, although their success has been limited. This is likely because the cross-talk between signaling pathways that coordinate eIF4F regulation with ternary complex formation after treatment with genotoxic therapeutics has not been fully explored. Here, we described...
Source: Signal Transduction Knowledge Environment - December 16, 2019 Category: Science Authors: Harvey, R. F., Pöyry, T. A. A., Stoneley, M., Willis, A. E. Tags: STKE Research Articles Source Type: news
Rhabdomyolysis risk with donepezil double that of other AD meds
Rhabdomyolysis more likely in those starting donepezil compared with rivastigmine or galantamine Related items fromOnMedica Suicide no more likely in men on 5 α-reductase inhibitors NICE calls for safer use of controlled drugs Falls risk just as high with trazodone as antipsychotics Over 75s not taking medication correctly, say GPs Debate goes on over valproate in pregnancy (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 15, 2019 Category: UK Health Source Type: news
Prescription medications for the treatment of insomnia and risk of suicide attempt: a comparative safety study - Lavigne JE, Hur K, Kane C, Au A, Bishop TM, Pigeon WR.
IMPORTANCE: Guidelines for the pharmacological treatment of chronic insomnia in adults recognize that trazodone and other off-label medications are commonly prescribed despite poor evidence. The Department of Veterans Health Affairs (VA) fills high volumes... (Source: SafetyLit)
Source: SafetyLit - June 8, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Antidepressant could 'improve old age for millions' by slowing the progression of Alzheimer's
Mood-boosting drug trazodone has been shown to slow neurodegenerative conditions in mice. The UK Dementia Research Institute will start the first human trials later this year. (Source: the Mail online | Health)
Source: the Mail online | Health - February 20, 2019 Category: Consumer Health News Source Type: news
Impact of Trazodone on Dementia Risk: New Data Impact of Trazodone on Dementia Risk: New Data
Animal studies suggest a potential role for trazodone in reducing dementia risk. New research in patients suggests the drug confers no protection and may even increase the risk.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - February 20, 2019 Category: Psychiatry Tags: Psychiatry News Source Type: news
Trazodone Not Associated With Reduced Risk for Dementia
Study refutes animal studies suggesting trazodone delays dementia in patients at prodromal stage (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 7, 2019 Category: Psychiatry Tags: Family Medicine, Geriatrics, Internal Medicine, Neurology, Pharmacy, Psychiatry, Journal, Source Type: news
Trazodone Not Associated With Reduced Risk for Dementia
THURSDAY, Feb. 7, 2019 -- Trazodone is not associated with a reduced risk for dementia compared with other antidepressants at the prodromal stage of disease, according to a study published online Feb. 5 in PLOS Medicine.
Ruth Brauer, Ph.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 7, 2019 Category: Pharmaceuticals Source Type: news
Blood test detects Alzheimer's years before symptoms
Changes in levels of a protein might reveal onset of disease more than 10 years before symptoms appear Related items fromOnMedica The increasing incidence of dementia Review shows link between herpes and dementia Use lumbar puncture to aid Alzheimer ’s disease diagnosis, doctors advised Falls risk just as high with trazodone as antipsychotics (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 23, 2019 Category: UK Health Source Type: news
Trazodone Associated With Risk of Falls, Fractures
(MedPage Today) -- But other atypical antipsychotics come with similar risk (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 1, 2018 Category: Psychiatry Source Type: news
Risks of Trazodone Similar to Those of Atypical Antipsychotics
Among older adults with dementia, rates of falls, fracture similar, but mortality rate lower (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 27, 2018 Category: Psychiatry Tags: Neurology, Pharmacy, Psychiatry, Geriatrics, Journal, Source Type: news
Risks of Trazodone Similar to Those of Atypical Antipsychotics
TUESDAY, Nov. 27, 2018 -- For older adults with dementia, trazodone is associated with a comparable risk for falls and fractures as that of atypical antipsychotics, according to a study published online Nov. 26 in CMAJ, the Journal of the Canadian... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 27, 2018 Category: Pharmaceuticals Source Type: news
Falls risk just as high with trazodone as antipsychotics
Trazodone similarly risky as antipsychotics for falls and major fractures, in elderly with dementia Related items fromOnMedica Antidepressant use increases risk of head injuries in Alzheimer's disease Hospitals must do more to prevent inpatient falls Risk of falls increases sharply in women during midlife Vitamin D supplements really don ’t stave off falls or boost bone mineral density (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 27, 2018 Category: UK Health Source Type: news
Low-dose trazodone, benzodiazepines, and fall-related injuries in nursing homes: a matched-cohort study - Bronskill SE, Campitelli MA, Iaboni A, Herrmann N, Guan J, Maclagan LC, Watt J, Rochon PA, Morris AM, Jeffs L, Bell CM, Maxwell CJ.
OBJECTIVES: To evaluate whether risk of fall-related injuries differs between nursing home (NH) residents newly dispensed low-dose trazodone and those newly dispensed benzodiazepines. DESIGN: Retrospective, matched cohort study in linked, populatio... (Source: SafetyLit)
Source: SafetyLit - October 5, 2018 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
