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These Antidepressants Are Most Effective, Study Says
Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults. The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women...
Source: TIME: Health - February 21, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

Trazodone Improves Some Measures of Sleep Quality Trazodone Improves Some Measures of Sleep Quality
Trazodone can improve some aspects of sleep quality in people with insomnia, according to data from a new meta-analysis.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 16, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

Depression drug that could slow Alzheimer's
During British trials, Trazodone was shown to reduce brain shrinkage in early tests – and as it has already been proven safe for humans, it could be on the market in two years. (Source: the Mail online | Health)
Source: the Mail online | Health - April 20, 2017 Category: Consumer Health News Source Type: news

Oleptro (Trazodone Hydrochloride Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 24, 2016 Category: Drugs & Pharmacology Source Type: news

Desyrel (Trazodone Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 24, 2016 Category: Drugs & Pharmacology Source Type: news

The 6 Medications You Should Never Take When Driving
It’s a given that safe driving needs concentration, alertness and an ability to react in a coordinated and timely fashion. But what may not occur to you is that the medications you’re taking can seriously impact all of these things. And it’s not just prescription medications, but over-the-counter products as well. “While laws differ from state to state, you can be charged with a DUI if caught driving hazardously while taking prescription or OTC meds, even if your doctor wrote you that prescription,” adds C. Michael White, Pharm.D., FCP, FCCP, Professor and Head of the Department of Pharmacy Pr...
Source: Healthy Living - The Huffington Post - October 4, 2016 Category: Consumer Health News Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Medication and Sleep
This article was adapted from a previous article written by Dr. Moore for his column “Kevlar for the Mind.” (Source: Psych Central)
Source: Psych Central - March 30, 2015 Category: Psychiatry Authors: Bret Moore, PsyD Tags: Anti-anxiety Antidepressants Atypical Antipsychotics Benzodiazepines Depression Disorders General Medications Sleep Insomnia sleep disorder Sleeping Pills Source Type: news

trazodone, Desyrel (discontinued brand)
Title: trazodone, Desyrel (discontinued brand)Category: MedicationsCreated: 3/26/1998 12:00:00 AMLast Editorial Review: 3/27/2015 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - March 27, 2015 Category: Psychiatry Source Type: news

NEJM discussion of ethylene glycol poisoning misses crucial points
2 out of 5 stars Case 4-2015: A 49-Year-Old Man with Obtundation Followed by Agitation and Acidosis. Cooper CM, Baron JM. N Engl J Med 2015 Jan 29;372:465-473. Reference This episode of the Journal‘s “Case Records of the Massachusetts General Hospital” series is the latest of their amazing inept discussions of medical toxicology cases. Yet again, the discussants do not include a medical toxicologist or emergency physician. Given the level of toxicological awareness evidenced by this case presentation, it’s fortunate that the patient did well. A unresponsive 49-year-old man was found outside wit...
Source: The Poison Review - February 3, 2015 Category: Toxicology Authors: Leon Tags: Medical case records of the massachusetts general hospital ethylene glycol poisoning fomepizole management medical toxicology new england journal of medicine Source Type: news

Veteran left with painful erection for WEEKS after rare reaction to Trazodone sleeping tablets
Edward Stalling, from Atlanta, U.S. says he has been left impotent and with difficulty urinating after a rare side effect to the common sleeping tablet Trazodone (file pic). (Source: the Mail online | Health)
Source: the Mail online | Health - January 8, 2015 Category: Consumer Health News Source Type: news

trazodone, Desyrel
Title: trazodone, DesyrelCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 7/1/2014 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 1, 2014 Category: Drugs & Pharmacology Source Type: news

trazodone, Desyrel
Title: trazodone, DesyrelCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 7/1/2014 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - July 1, 2014 Category: Psychiatry Source Type: news

What Are the Potential Side Effects of Trazodone?
Trazodone is an antidepressant most commonly used to treat insomnia, sometimes prescribed to help treat bipolar disorder. Trazodone's most common side effects include headache, mild dry mouth, nausea, dizziness or lightheadedness, unpleasant taste, and drowsiness. This list of the side effects of trazodone is organized from most common to rare. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - April 29, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Meds Don't Help Anymore
Tortoiseshell on our forum asked the following question: I feel it is time for me to change meds or add something to the current meds. I am currently on Pristiq 100mg/day and Lamictal 200 mg/day. Increasing the dose didn't help, but worsened the side effects. These meds worked relatively well for me for 3 years until last September I had very emotionally difficult situation and got into destructive relationship. It threw me back again. Since then I haven't been able to enjoy myself and life despite of going to counseling weekly. Just not getting better. I am seeing my psychiatrist next week. She is very flexible ab...
Source: About.com Depression - April 22, 2014 Category: Psychiatry Source Type: news

The effect of trazodone on standardized field sobriety tests - Ip EJ, Bui QV, Barnett MJ, Kazani A, Wright R, Serino MJ, Perry PJ.
STUDY OBJECTIVE: To evaluate the effects of a single dose of trazodone on the standardized field sobriety test (SFST). DESIGN: A randomized, double-blinded, repeated-measures study. PARTICIPANTS: Forty-five healthy adult subjects. SETTING: University campu... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 7, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Information about Some of the Newer 'Atypical'...
Information about some of the newer 'atypical' antidepressants - Buspar buspirone Desyrel trazodone Effexor venlafaxine Remeron mirtazapine Serzone nefazodone Wellbutrin bupropion. (Source: About.com Mental Health)
Source: About.com Mental Health - June 9, 2013 Category: Psychiatry Tags: health Source Type: news

Trazodone (Desyrel) Medication Profile
Trazodone is an antidepressant that is also sold under the brand name Desyrel. Trazodone is inexpensive and generally weight-neutral. It is also used as a sleep aid and to treat some other conditions including anxiety. Trazodone does have a large number of drug interactions, which may be problematic for people who take many medications. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - June 5, 2013 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Meds Don't Help Anymore
Tortoiseshell on our forum asked the following question: I feel it is time for me to change meds or add something to the current meds. I am currently on Pristiq 100mg/day and Lamictal 200 mg/day. Increasing the dose didn't help, but worsened the side effects. These meds worked relatively well for me for 3 years until last September I had very emotionally difficult situation and got into destructive relationship. It threw me back again. Since then I haven't been able to enjoy myself and life despite of going to counseling weekly. Just not getting better. I am seeing my psychiatrist next week. She is very flexible ab...
Source: About.com Depression - May 30, 2013 Category: Psychiatry Source Type: news

Effects of repeated dosing with mirtazapine, trazodone, or placebo on driving performance and cognitive function in healthy volunteers - Sasada K, Iwamoto K, Kawano N, Kohmura K, Yamamoto M, Aleksic B, Ebe K, Noda Y, Ozaki N.
This study aimed to evaluate the effects of repeated treatments with the sedative antidepressants mirtazapine and trazodone on driving performance and cognitive function. METHODS: Nineteen healthy men received continuous nocturnal doses of 15-mg... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 16, 2013 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Pediatric migraine drugs show limited or no efficacy
There is limited evidence supporting the efficacy of trazodone and topiramate in the prevention of pediatric episodic migraine headaches, show results from a meta-analysis. (Source: MedWire News - Pediatrics)
Source: MedWire News - Pediatrics - January 30, 2013 Category: Pediatrics Source Type: news

Anorgasmia With Trazodone
Question: "I just started on Trazodone  50 mg 3 times a day and noticed that it is much harder to achieve an orgasm. I could not have one with any of the SSRI's,  but my doctor told me this one should not cause this side effect.  Is it just me?  I never had this problem when I wasn't on antidepressants. I am in my 30's and a female."...Read Full Post (Source: About.com Depression)
Source: About.com Depression - January 27, 2013 Category: Psychiatry Source Type: news

Anorgasmia With Trazodone
Question: I just started on Trazodone  50 mg 3 times a day and noticed that it is much harder to achieve an orgasm. I could not have one with any of the SSRI's,  but my doctor told me this one should not cause this side effect.  Is it just me?  I never had this problem when I wasn't on antidepressants. I am in my 30's and a female....Read Full Post (Source: About.com Depression)
Source: About.com Depression - January 26, 2013 Category: Psychiatry Source Type: news