Removal of benzophenone-4 via chlorination and advanced oxidation processes in aqueous solution: kinetics, by-product identification, and mechanistic studies
In this study, we focus on the degradation of this compound by chlorine, and we report the efficiency of its removal from water by applying two advanced oxidation processes UV/TiO2 and UV/H2O2 aiming to achieve a superior mineralization result. The study was performed in purified water (pH = 6.5, temperature = 25 °C) with an initial concentration of BP-4 similar to that detected in WWTPs (10 mg/L). The results showed that 76% of BP-4 was degraded after 80 min of reaction with chlorine leading to the formation of one by-product persistent in the solution. The oxidation by UV/TiO2 and UV/H2O2 led to a total removal of BP-4 ...
Source: Environmental Science and Pollution Research International - April 16, 2024 Category: Environmental Health Authors: Lama Santbay Mounir Kassir Rania Nassar Samia Mokh Mohamad Al Iskandarani Ahmad Rifai Source Type: research
Heavy metal leaching from wood ash before and after hydration and carbonation
Environ Sci Pollut Res Int. 2024 Apr 16. doi: 10.1007/s11356-024-33221-0. Online ahead of print.ABSTRACTWood ashes can be used, e.g., as soil fertilizer or in construction materials; however, it is important to ensure that such use will not cause spreading of heavy metals and subsequent harm to the environment. Wood fly ashes (WFAs) generally have higher concentrations of heavy metals than wood bottom ashes. This paper focuses on the leaching of heavy metals from WFA, specifically identifying WFA characteristics that influence the leaching and changes in leaching caused by hydration and carbonation in ambient air. Chemomet...
Source: Environmental Science and Pollution Research International - April 16, 2024 Category: Environmental Health Authors: Lisbeth M Ottosen Nina M Sigvardsen Source Type: research
Photodynamic anticancer activity evaluation of novel 5-aminolevulinic acid and 3-hydroxypyridinone conjugates
In conclusion, cellular phototoxicity showed a strong correlation with intracellular PpIX fluorescence levels, indicating the potential application of ALA-HPO conjugates in ALA-PDT.PMID:38626642 | DOI:10.1016/j.bmc.2024.117726 (Source: Bioorganic and Medicinal Chemistry)
Source: Bioorganic and Medicinal Chemistry - April 16, 2024 Category: Chemistry Authors: Jingqi Zhang Shengli Yuan Miaoliang Fan Keren Wang Jianan Guo Anjie Zang Jinhui Ren Weike Su Changjun Zhang Yuanyuan Xie Source Type: research
The effect of EGCG/tyrosol-loaded chitosan/lecithin nanoparticles on hyperglycemia and hepatic function in streptozotocin-induced diabetic mice
In conclusion, the EGCG/tyrosol-loaded C/L NPs reduced hyperglycemia, oxidative stress, and inflammation in diabetic mice. These findings suggest that EGCG/tyrosol-loaded C/L NPs could be a promising therapeutic option for type 2 diabetes management.PMID:38626839 | DOI:10.1016/j.ijbiomac.2024.131496 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Ali Es-Haghi Mozhgan Soltani Masoud Homayouni Tabrizi Maryam Karimi Noghondar Nilofar Khatamian Niloofar Barati Naeeni Matin Kharaghani Source Type: research
Characterization of emulgels formulated with phycocyanin and diutan gum as a novel approach for biocompatible delivery systems
Int J Biol Macromol. 2024 Apr 14:131599. doi: 10.1016/j.ijbiomac.2024.131599. Online ahead of print.ABSTRACTPhycocyanin (PC), a protein derived from algae, is non-toxic and biocompatible. Due to its environmental and sustainable properties, it has been studied as an alternative stabilizer for food emulsions. In this sense, the main objective of this work is to evaluate the effectiveness of PC and its use in combination with diutan gum (DG), a biological macromolecule, to prepare emulgels formulated with avocado oil. Z-potential measurements show that the optimum pH for working with PC is 2.5. Furthermore, the system exhibi...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Patricia Tello Jenifer Santos V íctor M Perez-Puyana Alberto Romero Luis A Trujillo-Cayado Source Type: research
Degradation and humification of steroidal estrogens in the soil environment: a review
Chemosphere. 2024 Apr 14:142043. doi: 10.1016/j.chemosphere.2024.142043. Online ahead of print.ABSTRACTEmerging pollutants are toxic and harmful chemical substances characterized by environmental persistence, bioaccumulation and biotoxicity, which can harm the ecological environment and even threaten human health. There are four categories of emerging pollutants that are causing widespread concern, namely, persistent organic pollutants, endocrine disruptors, antibiotics, and microplastics. The distribution of emerging pollutants has spatial and temporal heterogeneity, which is influenced by factors such as geographical loc...
Source: Chemosphere - April 16, 2024 Category: Chemistry Authors: Qianhui Yang Weishan Liao Zebin Wei Rongliang Qiu Qian Zheng Qitang Wu Yangmei Chen Source Type: research
Degradation and humification of steroidal estrogens in the soil environment: a review
Chemosphere. 2024 Apr 14:142043. doi: 10.1016/j.chemosphere.2024.142043. Online ahead of print.ABSTRACTEmerging pollutants are toxic and harmful chemical substances characterized by environmental persistence, bioaccumulation and biotoxicity, which can harm the ecological environment and even threaten human health. There are four categories of emerging pollutants that are causing widespread concern, namely, persistent organic pollutants, endocrine disruptors, antibiotics, and microplastics. The distribution of emerging pollutants has spatial and temporal heterogeneity, which is influenced by factors such as geographical loc...
Source: Chemosphere - April 16, 2024 Category: Chemistry Authors: Qianhui Yang Weishan Liao Zebin Wei Rongliang Qiu Qian Zheng Qitang Wu Yangmei Chen Source Type: research
Gigantol, a promising natural drug for inflammation: a literature review and computational based study
Nat Prod Res. 2024 Apr 16:1-17. doi: 10.1080/14786419.2024.2340042. Online ahead of print.ABSTRACTGigantol, a bibenzyl compound extracted from various medicinal plants, has shown a number of biological activities, making it an attractive candidate for potential medical applications. This systematic review aims to shed light on gigantol's promising role in inflammation treatment and its underlying mechanisms. Gigantol exhibits potential anti-inflammatory properties in pre-clinical pharmacological test systems. It effectively reduced the levels of pro-inflammatory markers and arachidonic acid metabolites through various path...
Source: Natural Product Research - April 16, 2024 Category: Biochemistry Authors: Raihan Chowdhury Shimul Bhuia Asraful Islam Rakib Sakib Al Hasan Manik Chandra Shill Heba A S El-Nashar Mohamed El-Shazly Muhammad Torequl Islam Source Type: research
Efficacy of Maturase K and rpL20 protein extracted from C. procera leaves on Anopheles stephensi
Toxicon. 2024 Apr 14:107714. doi: 10.1016/j.toxicon.2024.107714. Online ahead of print.ABSTRACTThe present work is carried out to protein isolation, purification, and characterization from leaves, stem, and seed of C. procera and to evaluate the larvicidal potential on Anopheles stephensi. The whole protein was isolated using protein extraction buffer and precipitated by ammonium sulphate and larvicidal active protein was purified by the column chromatography. The homogeneity of larvicidal protein was confirmed by the SDS-PAGE. The identification of protein was done by the HPLC and LC-MS/ESI-MS. The crude protein from leav...
Source: Toxicon - April 16, 2024 Category: Toxicology Authors: Manisha Kirar S P Singh Hitesh Singh Neelam Sehrawat Source Type: research
Mechanisms of neurocentral-eyestalk-intestinal immunotoxicity in whiteleg shrimp Litopenaeus vannamei under ammonia nitrogen exposure
Environ Pollut. 2024 Apr 14:123956. doi: 10.1016/j.envpol.2024.123956. Online ahead of print.ABSTRACTAmmonia-N, as the most toxic nitrogenous waste, has high toxicity to marine animals. However, the interplay between ammonia-induced neuroendocrine toxicity and intestinal immune homeostasis has been largely overlooked. Here, a significant concordance of metabolome and transcriptome-based "cholinergic synapse" supports that plasma metabolites acetylcholine (ACh) plays an important role during NH4Cl exposure. After blocking the ACh signal transduction, the release of dopamine (DA) and 5-hydroxytryptamine (5-HT) in the cerebra...
Source: Environmental Pollution - April 16, 2024 Category: Environmental Health Authors: Ruixue Tong Yaobing Li Xin Yu Ning Zhang Qilong Liao Luqing Pan Source Type: research
Exposure to 7,12-dimethylbenz[a]anthracene impacts ovarian DNA damage sensing and repair proteins differently in lean and obese female mice and weight loss may mitigate obesity-induced ovarian dysfunction
Toxicol Appl Pharmacol. 2024 Apr 14:116930. doi: 10.1016/j.taap.2024.116930. Online ahead of print.ABSTRACTObesity impairs oocyte quality, fertility, pregnancy maintenance, and is associated with offspring birth defects. The model ovotoxicant, 7,12-dimethylbenz[a]anthracene (DMBA), causes ovarian DNA damage and follicle loss. Both DMBA-induced chemical biotransformation and the DNA damage response are partially attenuated in obese relative to lean female mice but whether weight loss could improve the DNA damage response to DMBA exposure has not been explored. Thus, at six weeks of age, C57BL/6 J female mice were divided in...
Source: Toxicology and Applied Pharmacology - April 16, 2024 Category: Toxicology Authors: M Estefan ía González-Alvarez Imaobong Inyang Aileen F Keating Source Type: research
Roxithromycin exposure induces motoneuron malformation and behavioral deficits of zebrafish by interfering with the differentiation of motor neuron progenitor cells
In this study, we used the zebrafish as a vertebrate model to explore the potential developmental toxicity of early ROX exposure, particularly focusing on its effects on locomotor functionality and CaP motoneuron development. Early exposure to ROX induces marked developmental toxicity in zebrafish embryos, significantly reducing hatching rates (n=100), body lengths (n=100), and increased malformation rates (n=100). The zebrafish embryos treated with a corresponding volume of DMSO (0.1%, v/v) served as vehicle controls (veh). Moreover, ROX exposure adversely affected the locomotive capacity of zebrafish embryos, and observa...
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Wenjie Xie Juntao Chen Xiaoqian Cao Jiannan Zhang Juanjuan Luo Yajun Wang Source Type: research
Developmental toxicity of short-chain chlorinated paraffins on early-stage chicken embryos in a shell-less (ex-ovo) incubation system
In conclusion, SCCPs induce developmental toxicity by disrupting thyroid functions at the early-life stage of chicken embryos.PMID:38626606 | DOI:10.1016/j.ecoenv.2024.116304 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Hao Chen Kaori Chigusa Kazuki Kanda Rumi Tanoue Mari Ochiai Hisato Iwata Source Type: research
Aflatoxin B1 inhibited the development of primary myoblasts of grass carp (Ctenopharyngodon idella) by degrading extracellular matrix
Ecotoxicol Environ Saf. 2024 Apr 15;276:116332. doi: 10.1016/j.ecoenv.2024.116332. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer (IARC), aflatoxin B1 (AFB1) has been recognized as a major contaminant in food and animal feed and which is a common mycotoxin with high toxicity. Previous research has found that AFB1 inhibited zebrafish muscle development. However, the potential mechanism of AFB1 on fish muscle development is unknown, so it is necessary to conduct further investigation. In the present research, the primary myoblast of grass carp was used as a model, we treated myobla...
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Xiang-Ning He Wei-Dan Jiang Pei Wu Yang Liu Hong-Mei Ren Xiao-Wan Jin Sheng-Yao Kuang Ling Tang Shu-Wei Li Lin Feng Xiao-Qiu Zhou Source Type: research
Effects of Streptomyces sp. HU2014 inoculation on wheat growth and rhizosphere microbial diversity under hexavalent chromium stress
Ecotoxicol Environ Saf. 2024 Apr 15;276:116313. doi: 10.1016/j.ecoenv.2024.116313. Online ahead of print.ABSTRACTWheat (Triticum aestivum L.) is a major foodstuff for over 40% of the world's population. However, hexavalent chromium [Cr(VI)] in contaminated soil significantly affects wheat production and its ecological environment. Streptomyces sp. HU2014 was first used to investigate the effects of Cr (VI) stress on wheat growth. We analyzed the Cr(VI) concentration, physicochemical properties of wheat and soil, total Cr content, and microbial community structures during their interactions. HU2014 reduced the toxicity of C...
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Hongxia Zhu Linfeng Hu Yunlong Wang Peipei Mei Feng Zhou Tetiana Rozhkova Chengwei Li Source Type: research
