Advances in Early Diagnosis
This article shows how some surprising technologies are improving the early detection of several conditions. Nutromics continuously monitors the delivery of an antibiotic used to treat sepsis. Eye-tracking from Tobii is used by several of its clients to detect certain kinds of autism as early as twelve months of age. And Cordio Medical is detecting oncoming congestive heart failure (CHF) three weeks in advance of an incident.
Minimally Invasive Monitoring Provides Real-Time Measurements
Although doctors learn what people have in their bodies most often through blood tests, technologies developed over the past few decades c...
Source: EMR and HIPAA - May 18, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT Telemedicine and Remote Monitoring ADOS Agim Beshiri AI Diagnosis Autism CHF Cordio Medical Eye Tracking Eye Tracking Sensors Healthcare Sensors HearO Karen Pierce Source Type: blogs
Evidence for Parkinson's Disease to Have a Bacterial Origin
This study aimed to investigate whether Desulfovibrio bacteria induce alpha-syn aggregation.
Fecal samples of ten PD patients and their healthy spouses were collected for molecular detection of Desulfovibrio species, followed by bacterial isolation. Isolated Desulfovibrio strains were used as diets to feed Caenorhabditis elegans nematodes which overexpress human alpha-syn fused with yellow fluorescence protein. Curli-producing Escherichia coli MC4100, which has been shown to facilitate alpha-syn aggregation in animal models, was used as a control bacterial strain, and E. coli LSR11, incapable of producing curli, was...
Source: Fight Aging! - May 16, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species.
We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Clinisys Acquires Promium to Further Grow Scientific, Environmental and Public Health Diagnostics Capabilities
Acquisition Solidifies Clinisys as a Market Leader in Public Health and Toxicology Diagnostics in North America; Continues Clinisys’ Global Expansion
Clinisys today announced that it has acquired Promium, a Bothell, Washington-based, leading provider of laboratory information management systems dedicated to supporting environmental, water, wastewater and other analytical testing laboratories that protect health and safety.
The addition of Promium to Clinisys provides an extra layer of industry expertise, knowledge and proven technology to Clinisys’ offerings and is another step toward fulfilling Clinisys’ vision of e...
Source: EMR and HIPAA - May 12, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT CliniSys Clinisys Laboratory Solutions Health IT Acquisitions Healthcare M&A Michael Simpson Promium Promium Element LIMS Solution Public Health SaaS Scot Cocanour Toxicology Diagnostics Source Type: blogs
R.I.P. Newton Minow
Paul MatzkoFormer FCC Chairman Newton Minow died a few days ago and outlets dug deep into their archives to dust off their pre‐written obits for the 97‐year‐old who lived a full and eventful life. I had the opportunity to be on a panel with Minow back in 2021, which was a somewhat surreal experience given how few of the people that I covered in mybook on broadcasting in the 1960s are still around. I have a few thoughts about his legacy to share with you.Let ’s start with a positive note. Minow often had solid foresight. For instance, he was right when hetold JFK that launching the first telecom...
Source: Cato-at-liberty - May 10, 2023 Category: American Health Authors: Paul Matzko Source Type: blogs
Reviewing T Cell Immunotherapies to Treat Cancer
The use of immunotherapies will most likely replace chemotherapy and radiation therapy for the treatment near all cancers over the next twenty years, and has already done so for many types of cancer. We should expect immunotherapies to in turn be replaced by approaches that target the telomere lengthening essential to all cancers. The wheel turns slowly, but this progress will lead steadily to an end to the suffering and loss of life accompanying cancer. Cancer will become a mild, annoying but controllable condition within a matter of decades, within the lifetimes of most of those reading this now. The review paper noted h...
Source: Fight Aging! - May 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
An Unusual Bradycardia
==================================Case Presentation by KEN GRAUER, MD (5/5/2023): — Edits by Drs. Meyers& Smith ...==================================Dr. Smith was reading ECGs — and he sent myself and Dr. Meyers the tracing shown in Figure-1. At the time we did not yet know the history ...What do YOU think?Figure-1: The initial ECG in today ' s case. No history yet ...Our Initial Thoughts on the ECG in Figure-1:Dr. Meyers said the following: " I see 2 different atrial foci — one sinus and one ectopic. There is AV block — but unclear why. T...
Source: Dr. Smith's ECG Blog - May 5, 2023 Category: Cardiology Authors: ECG Interpretation Source Type: blogs
Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs
Researchers at MIT have developed a nanoparticle system that is designed to deliver immunostimulatory drugs to tumors. These drugs are intended to stimulate immune cells in the vicinity of tumors to begin destroying tumor cells, but when delivered systemically they cause unacceptable dose limiting side-effects such as systemic inflammation. These particles are bottle-brush shaped, with the inactive drug being conjugated to the “brush backbone”. By tweaking the formulation of the particles, the researchers can fine tune their release profile, and have been able to create particles that will accumulate at the tumor witho...
Source: Medgadget - May 3, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine mit Source Type: blogs
This ‘ Good ’ Relationship Pattern Is Surprisingly Toxic
The pattern can even lead to depression and anxiety. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - May 2, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Relationships Source Type: blogs
Breakthrough trial shows MRI-guided radiation can reduce prostate cancer treatment toxicity
Nearly 290,000 American men will be diagnosed with prostate cancer in 2023. Thankfully, the vast majority will be diagnosed with clinically localized disease and can be cured with either surgery or radiotherapy. Emerging clinical trial data have cemented stereotactic body radiotherapy (SBRT), a form of radiation in which ≤5 daily doses are delivered with high
Read more…
Breakthrough trial shows MRI-guided radiation can reduce prostate cancer treatment toxicity originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 29, 2023 Category: General Medicine Authors: Amar U. Kishan, MD Tags: Conditions Oncology/Hematology Source Type: blogs
The Most Toxic Relationship Pattern Can Change
This toxic pattern can change as relationships mature. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 29, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Relationships Source Type: blogs
Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved.
Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
This Is The Most Toxic Relationship Pattern
The pattern is linked to anger, sadness, fear and even threats and aggression. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 22, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Relationships Source Type: blogs
The Moth Trap: How I came to see the lepidopteral light
Regular Sciencebase readers will know only too well that back in July 2018 I got hooked on moths. An enthusiastic friend lent me a moth trap he had built himself for his children many years ago. The trap is basically a wooden box with a plastic funnel and an ultraviolet light supported by stiff plastic vanes).
Moth trap
The UV light attracts the night-flying creatures, some of them bump into the vanes, drop into the funnel and then find a cozy corner in one of the empty egg cartons put inside the box before “lighting up”. The amateur, or indeed professional, lepidopterist examines the catch at dawn, recording s...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 18, 2023 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs
The Moth Trap: How I came to see the lepidopteral light and how you can too
TL:DR – How to fall in love with moths and mothing.
Regular Sciencebase readers will know only too well that back in July 2018 I got hooked on moths. An enthusiastic friend lent me a moth trap he had built himself for his children many years ago. The trap is basically a wooden box with a plastic funnel and an ultraviolet light supported by stiff plastic vanes).
Moth trap
The UV light attracts the night-flying creatures, some of them bump into the vanes, drop into the funnel and then find a cozy corner in one of the empty egg cartons put inside the box before “lighting up”. The amateur, or indeed professi...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 18, 2023 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs
