Carvedilol superior to metoprolol in MADIT-CRT analysis
The benefit of carvedilol over metoprolol was more pronounced in the subgroup of patients with a CRT-D, where carvedilol was associated with a significant 39% reduction in the risk of hospitalization for HF or death, and in those with left bundle branch block. (Source: theHeart.org)
Source: theHeart.org - April 2, 2013 Category: Cardiology Source Type: news
Carvedilol Beats Metoprolol in Some HF Patients (CME/CE)
(MedPage Today) -- Patients with mild heart failure and an implanted CRT-D device to regulate heart rhythm appear to do better with the beta-blocker carvedilol than with metoprolol, a subanalysis of MADIT-CRT suggested. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 2, 2013 Category: Cardiology Source Type: news
RCT: Metoprolol vs carvedilol, or carvedilol plus N-acetylcysteine on post-operative atrial fibrillation
Source: Eur Heart J
Area: News
The aim of this study was to evaluate the efficacy of metoprolol, carvedilol, and carvedilol plus NAC on the prevention of post-operative atrial fibrillation (POAF).
Three hundred and eleven patients undergoing cardiac surgery were randomised to metoprolol, carvedilol, or carvedilol plus NAC. The incidence of POAF was statistically lower in the carvedilol plus NAC group compared with the metoprolol group (P < 0.0001) or the carvedilol group (P = 0.03). Duration of hospitalisation was statistically lower in the carvedilol plus NAC group compared to the metoprolol group (P = 0.0...
Source: NeLM - Cardiovascular Medicine - February 22, 2013 Category: Cardiology Source Type: news
Metoprolol Succinate vs Ivabradine in Sinus TachycardiaMetoprolol Succinate vs Ivabradine in Sinus Tachycardia
Which agent is more favorable for inappropriate sinus tach? Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 23, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Benefits of beta blockers in patients with heart failure and reduced ejection fraction: network meta-analysis
Source: BMJ
Area: News
Beta blockers have been shown in randomised trials to prolong survival, prevent arrhythmia, improve symptoms of heart failure and left ventricular ejection fraction, and control ventricular rate, especially in patients with chronic heart failure. However, controversy exists as to the optimal selection of a particular agent for management of heart failure, as they differ in their selectivity for adrenergic receptors and their effects on the peripheral circulation.
This systematic review and network meta-analysis was conducted of efficacy of different beta- blockers in heart failure to clar...
Source: NeLM - Cardiovascular Medicine - January 17, 2013 Category: Cardiology Source Type: news
Elderly female with CHF complains of abdominal pain, nausea and vomiting, dizziness, and confusion for 5 days due to digoxin toxicity
Author: V. Dimov, M.D.Reviewer: S. Randhawa, M.D.Click here for thecase description and questions.What is the most likely diagnosis?Digoxin toxicity.Laboratory resultsFigure 1. Digoxin toxicity. Treatment with digoxin was started in the hospital and the patient was discharged to SNF, she was re-admitted 4 days later with digoxin toxicity.What would you do?Stop digoxin.Monitor digoxin levels.Control symptoms.Sitter in the room.What happened?The initial digoxin level was elevated at nearly twice the upper therapeutic level. All symptoms resolved as digoxin level decreased to therapeutic range. Heart rate was controlled by in...
Source: Clinical Cases and Images - August 2, 2009 Category: General Medicine Tags: Cardiology Intensive Care Toxicology Source Type: news
