Generic Versions of Toprol XL, a Heart Drug, Are Recalled
Recalls by two large Indian manufacturers, Wockhardt and Dr. Reddy’s Laboratories, are the latest in a string of recent problems involving generic drugs. (Source: NYT Health)
Source: NYT Health - June 24, 2014 Category: Consumer Health News Authors: By KATIE THOMAS Tags: India Drugs (Pharmaceuticals) Food and Drug Administration Dr Reddys Laboratories Ltd RDY NYSE Recalls and Bans of Products Novartis AG NVS NYSE Source Type: news
India Generic Blood Pressure Drugs Recalled Again in U.S.
India's Dr Reddy's Laboratoriesis recalling 13,560 bottles of the high blood pressure drug metoprolol succinate in the United States after the drug failed a dissolution test. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - June 19, 2014 Category: Pharmaceuticals Source Type: news
Dr Reddy's recalls over 13,000 bottles of hypertension drug: FDA
Dr Reddy's Laboratories Ltd is recalling 13,560 bottles of the high blood pressure drug metoprolol succinate in US after it failed a dissolution test. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 19, 2014 Category: Pharmaceuticals Source Type: news
Dr Reddy's recalls over 13,000 bottles of hypertension drug- FDA
MUMBAI (Reuters) - India's Dr Reddy's Laboratories Ltd is recalling 13,560 bottles of the high blood pressure drug metoprolol succinate in the United States after it failed a dissolution test, the U.S. Food and Drug Administration said. (Source: Reuters: Health)
Source: Reuters: Health - June 19, 2014 Category: Consumer Health News Tags: healthNews Source Type: news
Wockhardt recalls 8,712 bottles of hypertension drug in US market
Wockhardt is recalling over 8,000 bottles of anti-hypertension drug Metoprolol Succinate extended-release tablets following failure of a dissolution test. (Source: The Economic Times)
Source: The Economic Times - June 5, 2014 Category: Consumer Health News Source Type: news
India's Wockhardt Recalls Generic Heart Pills
Mumbai-based Wockhardt is recalling 109,744 bottles of its generic version of AstraZeneca's hypertension drug Toprol XL in the U.S. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - May 15, 2014 Category: Pharmaceuticals Source Type: news
FDA Planning Study of Generic Metoprolol Over Safety, Efficacy Concerns (FREE)
Extract
The FDA is planning an in-depth study of generic extended-release metoprolol succinate after receiving nearly 3500 complaints related to the blood pressure drug... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 9, 2014 Category: Primary Care Source Type: news
Do two dissimilar cases represent a case series?
2 out of 5 stars
High-dose Insulin and Intravenous Lipid Emulsion Therapy for Cardiogenic Shock Induced by Intentional Calcium-Channel Blocker and Beta-Blocker Overdose: A Case Series. Doepker B et al. J Emerg Med 2014 Apr;46:486-490.
Abstract
The problems with this confused and confusing paper start with the title, which suggests that it will describe a series patients who presented with overdose of a calcium-channel blocker (CCB) and beta-blocker (BB), who were treated with high-dose insulin (HDI) and intravenous lipid emulsion (ILE).
Well, this may be a case series, but the series includes only 2 patients, and ...
Source: The Poison Review - April 3, 2014 Category: Toxicology Authors: Leon Tags: Medical beta blocker overdose calcium channel blocker overdose high-dose insulin intralipid intravenous fat emulsion Source Type: news
Benefits of treating heart attack patients with a cheap drug
One dose of the drug metoprolol, if given to heart attack patients early -- during ambulance transit to hospital -- can significantly improve the contractile strength of the heart muscle. And this improvement is maintained for at least six months after the intervention, according to new results. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 30, 2014 Category: Science Source Type: news
Asystole shortly after intravenous fat emulsion for overdose: causation or coincidence?
3 out of 5 stars
Asystole Immediately Following Intravenous Fat Emulsion for Overdose. Cole JB et al. J Med Toxicol 2014 Feb 12. [Epub ahead of print]
Abstract
This case paper describes 2 patients who developed asystolic within 60 seconds of being given intravenous fat emulsion (IFE) bolus for treatment of severe cardiotoxicity. Both patients had return of spontaneous circulation (ROSC) after several minutes of cardiopulmonary resuscitation. Unfortunately, both patients died days after admission from multisystem organ failure.
Patient A, a 50-year-old woman, had ingested an undetermined about of metoprolol and bupropion...
Source: The Poison Review - February 18, 2014 Category: Toxicology Authors: Leon Tags: Medical asystole bupropion cardiac arrest diltiazem intralipid intravenous fat emulsion therapy metoprolol propranolol Source Type: news
Wockhardt’s Main Drug Plant Added to FDA's "Red List"
The plant makes generic of Toprol-XL, a heart pill that accounts for about 14 percent of its sales (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 2, 2013 Category: Pharmaceuticals Source Type: news
Cardio Notes: IV Beta-Blocker Early on Shrinks Infarcts
(MedPage Today) -- The METOCARD-CNIC trial showed that intravenous metoprolol before patients go to the cath lab could have some benefit. Also, group heart failure appointments satisfied patients and office staff alike. (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - October 7, 2013 Category: Consumer Health News Source Type: news
Cardio Notes: IV Beta-Blocker Given Early Shrinks Infarcts
(MedPage Today) -- The METOCARD-CNIC trial showed that intravenous metoprolol before patients go to the cath lab could have some benefit. Also, group heart failure appointments satisfied patients and office staff alike. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 7, 2013 Category: Cardiology Source Type: news
CNIC researchers minimize damage during a heart attack with a drug costing less than €2.00
(Centro Nacional de Investigaciones Cardiovasculares) Early treatment--during ambulance or helicopter transit to the hospital--with metoprolol, a cheap drug available for more than 30 years, significantly reduces damage to the heart during a myocardial infarction, according to the results of the METOCARD-CNIC study published in the latest edition of Circulation, the leading journal in the cardiovascular field. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 1, 2013 Category: Global & Universal Source Type: news
Inexpensive drug costing less than 3 dollars may minimize damage from heart attack
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Early treatment of heart attack patients with an inexpensive beta-blocker drug called metoprolol, while in transit to the hospital, can significantly reduce damage to the heart during a myocardial infarction. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 1, 2013 Category: Global & Universal Source Type: news
