Does dosing of drug for mom make a difference for baby's risk of cleft lip, palate?
(American Academy of Neurology) Taking a higher dose of topiramate during the first three months of pregnancy may increase a baby's risk of cleft lip or cleft palate more than when taking a lower dose, according to a study published in the Dec. 27, 2017, online issue of Neurology ® , the medical journal of the American Academy of Neurology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 27, 2017 Category: International Medicine & Public Health Source Type: news
Topiramate in Early Pregnancy Increases Risk of Oral Clefts
Study finds that taking a higher dose of the drug in the first trimester increases risk of cleft lip or cleft palate more than taking a lower dose. (Source: BWH for Journalists)
Source: BWH for Journalists - December 27, 2017 Category: Research Source Type: news
No magic pill to cure alcohol dependence yet
(Society for the Study of Addiction) A new study published by the scientific journal Addiction has found no reliable evidence for using nalmefene, naltrexone, acamprosate, baclofen or topiramate to control drinking in patients with alcohol dependence or alcohol use disorder. At best, some treatments showed low to medium efficacy in reducing drinking, but those findings were from studies with a high risk of bias. None demonstrated any benefit on health outcomes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 21, 2017 Category: International Medicine & Public Health Source Type: news
Perampanel with concomitant levetiracetam and topiramate: post hoc analysis of adverse events related to hostility and aggression - Chung S, Williams B, Dobrinsky C, Patten A, Yang H, Laurenza A.
In 4 Phase III registration trials (3 in patients with partial seizures, N=1480; 1 in patients with PGTCS, N=163), perampanel administered to patients already receiving 1-3 concomitant antiepileptic drugs (AEDs) demonstrated statistically superior efficacy... (Source: SafetyLit)
Source: SafetyLit - August 24, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
FDA Drug Safety Communication: Risk of oral clefts in children born to mothers taking Topamax (topiramate)
[03-04-2011] The U.S. Food and Drug Administration (FDA) is informing the public of new data that show that there is an increased risk for the development of cleft lip and/or cleft palate (oral clefts) in infants born to women treated with Topamax (topiramate) during pregnancy. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 4, 2017 Category: Drugs & Pharmacology Source Type: news
Short-term adjunct of topiramate to antipsychotics in schizophrenia improves the psychopathology and has weight maintenance
This study included RCTs of antipsychotic cotreatment with topiramate in patients with schizophrenia-spectrum disorders (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 21, 2017 Category: Consumer Health News Source Type: news
Topamax (Topiramate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 26, 2017 Category: Drugs & Pharmacology Source Type: news
9 Surprising Reasons You Have A Headache
For Allure, by Cassie Shortsleeve.
Headaches have a special kind of way of ruining even the best of days. And it seems just about anything (those super elegant candles you just splurged on, your aunt’s voice, that third glass of wine...) can cause finicky little beasts to start banging tambourines in your brain.
If you feel like you have specific headache triggers, you probably do. Most headaches have them, but it can be difficult to pinpoint exactly what caused the paint to come on in the first place. “There are probably 1,000 causes of headaches,” says Mark W. Green M.D., director of headache and pain ...
Source: Healthy Living - The Huffington Post - April 17, 2017 Category: Consumer Health News Source Type: news
Qudexy XR (Topiramate Extended-Release Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 17, 2017 Category: Drugs & Pharmacology Source Type: news
Once-Daily Topiramate Approved for Migraine Prophylaxis Once-Daily Topiramate Approved for Migraine Prophylaxis
Extended-release capsules get the final FDA go-ahead for migraine prevention in both adults and adolescents aged 12 years and older who have migraine headaches.FDA Approvals (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - March 31, 2017 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news
FDA Approves Expanded Indication for Qudexy XR (topiramate) Extended-Release Capsules to Include Prophylaxis of Migraine Headache in Adults and Adolescents
MAPLE GROVE, Minn., March 30, 2017 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. (Upsher-Smith) today announced that it has received U.S. Food and Drug Administration (FDA) final approval of two supplemental new drug applications (sNDAs) for... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 30, 2017 Category: Drugs & Pharmacology Source Type: news
Qsymia (Phentermine and Topiramate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 6, 2017 Category: Drugs & Pharmacology Source Type: news
Trokendi XR (Topiramate Extended-release Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 30, 2016 Category: Drugs & Pharmacology Source Type: news
Topiramate for acute affective episodes in bipolar disorder in adults
Bipolar disorder is a common recurrent illness with high levels of chronicity. Previous trials have suggested that the anticonvulsant topiramate may be efficacious in bipolar disorder. This is an update of a previous Cochrane review (last published 2006) on the role of topiramate in bipolar disorder.
To assess the effects of topiramate for acute mood episodes in bipolar disorder in adults compared to placebo, alternative pharmacological treatment, and combination pharmacological treatment as measured by treatment of symptoms on specific rating scales for individual episodes. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 3, 2016 Category: Consumer Health News Source Type: news
Weight Loss Pills And Products Don't Work And Aren't Safe
Our ancestors lived in a feast or famine world. When you don't know where your next meal is coming from, or when it will arrive, the smart play is to pig out every time food is available. Our genes are programmed to extract as much energy as possible from what we eat and to store any extra energy in fat reservoirs, available in reserve for future famines.
These deeply ingrained genetic tendencies worked great in the austere world of our ancestors, but are a disaster in our current world of refrigerators, ubiquitous fast food joints and milk shakes.
Only one third of Americans are now able to maintain a normal weight; one ...
Source: Science - The Huffington Post - September 5, 2016 Category: Science Source Type: news
