AstraZeneca enlists UK Treg biotech for type 1 diabetes, inflammatory bowel disease deal featuring $85M upfront
AstraZeneca is partnering with Quell Therapeutics to develop regulatory T cell therapies for type 1 diabetes and inflammatory bowel disease, joining the growing movement of companies and academic groups developing cell therapies for autoimmune diseases.…#quell #1diabetes #academic #royalties (Source: Reuters: Health)
Source: Reuters: Health - June 9, 2023 Category: Consumer Health News Source Type: news
Akero ’s NASH candidate reduces liver fat in patients taking a GLP-1
Akero Therapeutics said its NASH drug reduced liver fat in patients who were also taking a GLP-1 agonist. The NASH-focused biotech on Monday released topline data from a Phase IIb trial for 32 patients with type 2 diabetes and F1-F3 liver fibrosis due to NASH who…#glp1 #nash #2diabetes #f1f3 #symmetry #f1 #f3 #unlock (Source: Reuters: Health)
Source: Reuters: Health - June 6, 2023 Category: Consumer Health News Source Type: news
Why Does He Rock His Body?
Discussion
Stereotypies are “…patterned, repetitive, purposeless, involuntary movements that are also rhythmic and continual and tend to change little over time.” They occur at all times of the day, and can get worse with stress or heightened emotions including happiness. Stereotypies more often occur in children with developmental disabilities (up to 61%), sensory impairments (e.g. blindness) or social deprivation. They can be present more often in patients with autism (up to 88%). They can be seen in ~7% of normally developing children too. Their onset is before age 3 years and tend to improve over year...
Source: PediatricEducation.org - May 22, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Prion Disease in Human Tears; Functional vs Primary Tics; COVID-19 and the Brain
(MedPage Today) -- Misfolded prion protein was detectable in tear fluid of people with Creutzfeldt-Jakob disease. (New England Journal of Medicine)
Autologous hematopoietic stem cell transplants showed benefit over fingolimod (Gilenya) and natalizumab... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - May 16, 2023 Category: Neurology Source Type: news
What Are the Symptoms of Serotonin Syndrome?
Discussion
Serotonin syndrome (SS) is a clinical diagnosis and problem which can be seen in patients of all ages. Classically SS presents with changing mental status, autonomic dysfunction and neuromuscular excitability. It is caused by increased serotonin levels because of therapeutically increasing the dose of a medication already being taken, adding an additional serotoninergic medication or one that potentiates serotonin, overlapping transition when changing medications, or intentional or unintentional overdose. It has become more common especially as selective serotonin reuptake inhibitors (SSRIs) have been used more ...
Source: PediatricEducation.org - May 8, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Can brains bounce back? Recovering addicts turn to science to map the effects of meth
Cohen Irwin is part of a group of former addicts in New Zealand working with researchers to trace signs of healing in the brains of those who stop smokingEvery few months, Cohen “Coey” Irwin lies on his back and lets the walls close in. Lights move overhead, scanning over the tattoos covering his cheeks. He lies suspended, his head encased by a padded helmet, ears blocked, as his body is shunted into a tunnel. The noise begins: a rhythmic crashing, loud as a jackhammer. For the next hour, an enormous magnet will produce finely detailed images of Irwin’s brain.Irwin has spent much of his adult life addicted to smoking...
Source: Guardian Unlimited Science - May 6, 2023 Category: Science Authors: Tess McClure in Gisborne Tags: New Zealand Drugs Science World news Source Type: news
Identifying high-risk phenotypes and associated harms of delayed time-to-antibiotics in patients with ICU onset sepsis: A retrospective cohort study
Conclusions: Septic patients with respiratory or cardiovascular dysfunction were associated with harms of delayed time-to-antibio tics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 14, 2023 Category: Consumer Health News Source Type: news
Tourette's tics reduced using electrical wrist device
(Source: Reuters: Health)
Source: Reuters: Health - March 12, 2023 Category: Consumer Health News Source Type: news
Tourette's device tested by Lewis Capaldi reduces tics in trial
A trial of 121 people finds they experienced, on average, a reduction in tic frequency of 25%. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 11, 2023 Category: Consumer Health News Source Type: news
Tangled in bankruptcy proceedings and legal tussle, Sorrento secures $75M to stay afloat
Sorrento Therapeutics can keep the lights on for now. Days after filing its Chapter 11 paperwork, the San Diego-based biotech said a bankruptcy court in Texas has granted interim approval for a $75 million financing that will fund its operations while it sorts out its…#sandiego #patricksoonshiong #venture #parentcompany #develop #chapter11filing #jmbcapitalpartners (Source: Reuters: Health)
Source: Reuters: Health - February 23, 2023 Category: Consumer Health News Source Type: news
How Teens Recovered From the ‘TikTok Tics’
A wave of teenagers who developed tics during the pandemic has receded, illustrating the powerful influence of stress on the body and the resilience of adolescents. (Source: NYT Health)
Source: NYT Health - February 13, 2023 Category: Consumer Health News Authors: Azeen Ghorayshi and Amber Bracken Tags: Social Media Teenagers and Adolescence Transgender and Transsexuals Computers and the Internet Anxiety and Stress Mental Health and Disorders Women and Girls Psychology and Psychologists Research Source Type: news
Patient death spurs trial halt for Magenta Therapeutics
Magenta Therapeutics is pausing an early-stage clinical trial after a patient died. The death was deemed to be possibly related to its drug, MGTA-117. The biotech said the pause of the Phase I/II trial is voluntary and gives it time to review all available data before…#fda #conjugate #cancerpatients #myeloid #grade4respiratory #classify #grade5 (Source: Reuters: Health)
Source: Reuters: Health - January 26, 2023 Category: Consumer Health News Source Type: news
Tourette's teen has experimental chip implanted under his skin which zaps away tics
Seventeen-year-old Callum deQuevedo, from Pennsylvania, was plagued by severe tics for three years, which included screaming, cursing and hitting himself in the head. (Source: the Mail online | Health)
Source: the Mail online | Health - January 20, 2023 Category: Consumer Health News Source Type: news
Ecopipam Reduces Tourette s Tics Without Common Side Effects Ecopipam Reduces Tourette s Tics Without Common Side Effects
It"may be a safe and effective treatment of Tourette syndrome with advantages over other currently approved therapeutic agents."Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 19, 2023 Category: Consumer Health News Tags: Pediatrics News Source Type: news
Ecopipam Reduces Tourette's Tics Without Common Side Effects Ecopipam Reduces Tourette's Tics Without Common Side Effects
It"may be a safe and effective treatment of Tourette syndrome with advantages over other currently approved therapeutic agents."Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 19, 2023 Category: Consumer Health News Tags: Pediatrics News Source Type: news
