Application and risk prediction of thrombolytic therapy in cardio-cerebrovascular diseases: a review
Cardiocerebrovascular diseases (CVDs) are the leading cause of death worldwide, consuming huge healthcare budget. For CVD patients, the prompt assessment and appropriate administration is the crux to save life... (Source: Thrombosis Journal)
Source: Thrombosis Journal - September 4, 2023 Category: Hematology Authors: Kexin Zhang, Yao Jiang, Hesong Zeng and Hongling Zhu Tags: Research Source Type: research

Comparing 5G mobile stroke unit and emergency medical service in patients acute ischemic stroke eligible for t ‐PA treatment: A prospective, single‐center clinical trial in Ya'an, China
ConclusionsOur findings indicate that 5G MSU care significantly reduces the time from symptom onset to stroke diagnosis and intravenous thrombolysis in patients with AIS, resulting in improved functional outcomes compared to EMS care. As China continues its deployment of 5G technology and other digital infrastructures, the adoption of 5G MSU care on a broader scale may eventually supplant traditional stroke treatment approaches. (Source: Brain and Behavior)
Source: Brain and Behavior - August 26, 2023 Category: Neurology Authors: Bo Zheng, Yan Li, Gangfeng Gu, Jian Yang, Junyao Jiang, Zhao Chen, Yang Fan, Sheng Wang, Han Pei, Jian Wang Tags: ORIGINAL ARTICLE Source Type: research

Thromboembolic Disease
Venous thromboembolism (VTE) encompasses deep vein thrombosis and pulmonary embolism, both of which can present on a spectrum from subtle symptoms to life- and limb-threatening emergencies. Some risk factors for VTE overlap cardiovascular risk factors and statin therapy can somewhat reduce the VTE risk. When presentations are not life-threatening, clinical prediction scores using the Well ’s criteria are best used to determine diagnostic testing. The mainstay of VTE treatment is anticoagulant therapy, although life- and limb-threatening presentations can also require thrombolytic therapy. (Source: Primary Care: Clinics in Office Practice)
Source: Primary Care: Clinics in Office Practice - August 26, 2023 Category: Primary Care Authors: Michael J. Arnold Source Type: research

The efficacy and safety of post-stroke cognitive impairment therapies: an umbrella review
Conclusion: Our study demonstrated that ACEI inhibitors (Donepezil) and NMDA antagonists (Memantine), EGB761, and acupuncture are the ADL and BI, MoCA, and neurological function deficit medication/therapy, respectively, for patients with PSCI.Clinical Trial Registration:https://inplasy.com/inplasy-2022-11-0139/; Identifier: INPLASY2022110139. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 24, 2023 Category: Drugs & Pharmacology Source Type: research

Effect of teleconsultation on the application of thrombolytic therapy in stroke patients in the emergency department
ConclusionsTeleconsultation was a successful and reliable strategy in assessing patients with ischemic stroke and making decisions for IV-tPA. Moreover, patient assessment via teleconsultation was less time consuming. The results of the study are promising for the use of teleconsultation in the future. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 19, 2023 Category: General Medicine Source Type: research

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712 (Source: Vascular)
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712 (Source: Vascular)
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712 (Source: Vascular)
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712 (Source: Vascular)
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research

Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.PMID:37577766 | DOI:10.14503/THIJ-23-8113 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - August 14, 2023 Category: Cardiology Authors: Yu Zhang Yu Qiu Jinming Luo Jian Zhang Qingqing Yan Source Type: research