Thrombocytopenia Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway
CONCLUSIONS: Alnustone can promote megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway and thus provides a new therapeutic strategy for the treatment of thrombocytopenia.PMID:38570080 | DOI:10.1016/j.ejphar.2024.176548 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 3, 2024 Category: Drugs & Pharmacology Authors: Yueyue Li Jia Lai Mei Ran Taian Yi Ling Zhou Jiesi Luo Xiaoxi Liu Xiaoqin Tang Miao Huang Xiang Xie Li Hong Yan Yang Wenjun Zou Jianming Wu Source Type: research

Clinical value of coagulation parameters in predicting the severity of severe fever with thrombocytopenia syndrome
DiscussionThe monitoring of the coagulation parameters in patients with SFTS is great significance for identifying the severity and death of the patient’s condition, and it is of great clinical value to provide early attention, timely intervention and maximum reduction of the mortality rate for patients at risk of severe disease. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - April 3, 2024 Category: Microbiology Source Type: research

 Erratum to: Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia
Haematologica. 2024 Apr 1;109(4):3010. doi: 10.3324/haematol.2023.284815.NO ABSTRACTPMID:38562076 | DOI:10.3324/haematol.2023.284815 (Source: Haematologica)
Source: Haematologica - April 2, 2024 Category: Hematology Authors: Srdan Verstovsek Ruben Mesa Moshe Talpaz Jean-Jacques Kiladjian Claire N Harrison Stephen T Oh Alessandro M Vannucchi Raajit Rampal Bart L Scott Sarah A Buckley Adam R Craig Karisse Roman-Torres John O Mascarenhas Source Type: research

Bernard-Soulier syndrome caused by two novel heterozygous GP1BA gene mutations: a case report and literature review
CONCLUSION: This case report describes two novel gene mutation sites that have not been reported previously, enriching understanding of the GP1BA mutation spectrum.PMID:38564005 | DOI:10.1080/16078454.2024.2334642 (Source: Hematology)
Source: Hematology - April 2, 2024 Category: Hematology Authors: Senlin Zhang Jing Ling Kai Cui Shihong Zhan Jiajia Zheng Wenyi Wang Junjie Fan Shaoyan Hu Source Type: research

 Erratum to: Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia
Haematologica. 2024 Apr 1;109(4):3010. doi: 10.3324/haematol.2023.284815.NO ABSTRACTPMID:38562076 | PMC:PMC10988197 | DOI:10.3324/haematol.2023.284815 (Source: Haematologica)
Source: Haematologica - April 2, 2024 Category: Hematology Authors: Srdan Verstovsek Ruben Mesa Moshe Talpaz Jean-Jacques Kiladjian Claire N Harrison Stephen T Oh Alessandro M Vannucchi Raajit Rampal Bart L Scott Sarah A Buckley Adam R Craig Karisse Roman-Torres John O Mascarenhas Source Type: research

Antiphospholipid syndrome, thrombosis, and vaccination in the COVID-19 pandemic
AbstractThrombosis is one of the many signs of antiphospholipid syndrome (APS) and COVID-19 infection. Although the mechanisms contributing to thrombosis in APS and COVID-19 are relatively similar, this remains an open subject. Even now (when the COVID-19 pandemic has subsided), there is no conclusive solution to APS and COVID-19 co-occurrence. The presence of newly generated antiphospholipid antibodies (aPLs) in COVID-19 infection may or may not be connected to the diagnosis of APS. The prevalence of aPLs is substantial in severe COVID-19 but not related to thrombosis or a worse outcome. Adequate monitoring of antibody po...
Source: Rheumatology International - April 2, 2024 Category: Rheumatology Source Type: research

A real ‐world retrospective–prospective analysis of efficacy and safety of combined ixazomib, lenalidomide, and dexamethasone in relapsed/refractory multiple myeloma: The northern Italy experience
ConclusionIRd might be effective and safe in RRMM pts with an indolent disease, in early lines of treatment, and who proved Len-sensitive, independent of age, and cytogenetic risk. (Source: Cancer Medicine)
Source: Cancer Medicine - April 1, 2024 Category: Cancer & Oncology Authors: Anna Furlan, Michele Cea, Laura Pavan, Monica Galli, Cristina Clissa, Silvia Mangiacavalli, Anna Maria Cafro, Stefania Girlanda, Francesca Patriarca, Claudia Minotto, Giovanni Bertoldero, Gregorio Baril à, Anna Pascarella, Albana Lico, Ross Tags: RESEARCH ARTICLE Source Type: research

Why might cord blood be a better source of platelets for transfusion to neonates?
Blood Transfus. 2024 Mar 27. doi: 10.2450/BloodTransfus.566. Online ahead of print.ABSTRACTThrombocytopenia (defined as a platelet count <150×109/L) is a common condition in preterm neonates and may occur in 18-35% of all infants admitted to the Neonatal Intensive Care Unit (NICU). Neonatal platelet functionality in terms of reactivity is often described as reduced compared to adults, even in healthy, term neonates. However, this platelet "hyporeactivity" does not correspond to a global functional impairment of the normal delicately balanced neonatal hemostatic system. The extent to which neonatal thrombocytopenia and ...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Valeria Cortesi Giacomo Cavallaro Genny Raffaeli Stefano Ghirardello Fabio Mosca Thomas R L Klei Suzanne Fustolo-Gunnink Simon Stanworth Helen V New Em öke Deschmann Enrico Lopriore Source Type: research