A Randomized, Blinded, Placebo-controlled, Phase II Trial of LEE011 in Patients With Relapsed, Refractory, Incurable Teratoma With Recent Progression
Condition:  TeratomaInterventions:  Drug: LEE011;  Drug: LEE011 PlaceboSponsor:  Novartis PharmaceuticalsRecruiting - verified March 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 15, 2014 Category: Research Source Type: clinical trials
A Randomized, Blinded, Placebo-controlled, Phase II Trial of LEE011 in Patients With Relapsed, Refractory, Incurable Teratoma With Recent Progression
Condition:  TeratomaInterventions:  Drug: LEE011;  Drug: LEE011 PlaceboSponsor:  Novartis PharmaceuticalsNot yet recruiting - verified November 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 15, 2014 Category: Research Source Type: clinical trials
Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors
Conditions:  Adult Central Nervous System Germ Cell Tumor;  Adult Teratoma;  Malignant Extragonadal Germ Cell Tumor;  Malignant Extragonadal Non-Seminomatous Germ Cell Tumor;  Extragonadal Seminoma;  Recurrent Malignant Testicular Germ Cell Tumor;  Recurrent Ovarian Germ Cell Tumor;  Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor;  Stage IV Extragonadal Seminoma;  Stage IV Ovarian Germ Cell TumorIntervention:  Drug: palifosfamideSponsors:  Indiana University School of Medicine;  ZiopharmRecruiting - verified January 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2013 Category: Research Source Type: clinical trials
DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings
Conditions:  Childhood Malignant Ovarian Germ Cell Tumor;  Childhood Malignant Testicular Germ Cell Tumor;  Ovarian Choriocarcinoma;  Ovarian Embryonal Carcinoma;  Ovarian Mixed Germ Cell Tumor;  Ovarian Teratoma;  Ovarian Yolk Sac Tumor;  Testicular Choriocarcinoma;  Testicular Embryonal Carcinoma;  Testicular Seminoma;  Testicular Teratoma;  Testicular Yolk Sac TumorInterventions:  Other: laboratory biomarker analysis;  Other: questionnaire administrationSponsors:  Children's Oncology Group;  National Cancer Institute (NCI)Recruiting - verified May...
Source: ClinicalTrials.gov - September 13, 2011 Category: Research Source Type: clinical trials
Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia
Conditions:  Childhood Atypical Teratoid/Rhabdoid Tumor;  Childhood Central Nervous System Choriocarcinoma;  Childhood Central Nervous System Germinoma;  Childhood Central Nervous System Mixed Germ Cell Tumor;  Childhood Central Nervous System Teratoma;  Childhood Central Nervous System Yolk Sac Tumor;  Childhood Choroid Plexus Tumor;  Childhood Craniopharyngioma;  Childhood Ependymoblastoma;  Childhood Grade I Meningioma;  Childhood Grade II Meningioma;  Childhood Grade III Meningioma;  Childhood Infratentorial Ependymoma;  Childhood Medulloepithelioma;  ...
Source: ClinicalTrials.gov - March 16, 2010 Category: Research Source Type: clinical trials
Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy
Conditions:  Cognitive Side Effects of Cancer Therapy;  Malignant Ovarian Mixed Epithelial Tumor;  Malignant Ovarian Surface Epithelial-Stromal Tumor;  Ovarian Brenner Tumor;  Ovarian Carcinosarcoma;  Ovarian Choriocarcinoma;  Ovarian Clear Cell Cystadenocarcinoma;  Ovarian Dysgerminoma;  Ovarian Embryonal Carcinoma;  Ovarian Endometrioid Adenocarcinoma;  Ovarian Mixed Germ Cell Tumor;  Ovarian Mucinous Cystadenocarcinoma;  Ovarian Polyembryoma;  Ovarian Sarcoma;  Ovarian Serous Cystadenocarcinoma;  Ovarian Teratoma;  Ovarian Yolk Sac Tumor;  Stage IÂ...
Source: ClinicalTrials.gov - March 3, 2010 Category: Research Source Type: clinical trials
