TTField in Combination With TMZ and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.
Conditions: Glioblastoma Multiforme Interventions: Device: Tumor Treating Fields; Drug: Tislelizumab; Drug: Temozolomide (TMZ) Sponsors: Jiangsu Healthy Life Innovation Medical Technology Co., Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)
Conditions: Advanced or Metastatic NRAS-mutant Melanoma Interventions: Drug: Naporafenib; Drug: Dacarbazine; Drug: Temozolomide; Drug: Trametinib Sponsors: Erasca, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials
Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma
Conditions: Glioma Interventions: Drug: Temozolomide （TMZ） injection or oral administration; Drug: Albumin-Bound Paclitaxel(ABX) intravenous drip; Device: Specific mode electroacupuncture stimulation(SMES) intervention Sponsors: The Third Affiliated hospital of Zhejiang Chinese Medical University; Zhejiang University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
Evaluate the Efficacy and Safety of Atorvastatin Combined With Temozolomide in the Treatment of Glioblastoma
Conditions: Glioblastoma, IDH-wildtype Interventions: Drug: Atorvastatin 20mg Sponsors: Tianjin Medical University General Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).
Conditions: Glioblastoma Interventions: Drug: Radiotherapy, Temozolomide, Doxorubicin Sponsors: Iacopo Sardi Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma
Conditions: Glioblastoma; Cancer; Temozolomide Interventions: Drug: 6-mercaptopurine Sponsors: The First Affiliated Hospital with Nanjing Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)
Conditions: Glioblastoma; Glioblastoma Multiforme; Glioblastoma, IDH-wildtype; Glioblastoma Multiforme of Brain; Glioblastoma Multiforme, Adult; Recurrent Glioblastoma; Astrocytoma, Malignant; Astrocytoma of Brain Interventions: Procedure: Re-resection; Drug: Temozolomide; Drug: Lomustine; Radiation: Re-irradiation; Procedure: Experimental therapy; Other: Best supportive care Sponsors: Jasper Gerritsen; Haaglanden Medical Centre; Universitaire Ziekenhuizen KU Leuven; University Hospital Heidelberg; Technical University of Munich; Insel Gruppe AG, University Hospital Bern; Massachusetts General Hospital; University of Calif...
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Niraparib and Temozolomide in Patients Glioblastoma
Conditions: Glioma, Malignant Interventions: Drug: Temodal; Drug: Niraparib Sponsors: Armando Santoro, MD; Istituto Clinico Humanitas; GlaxoSmithKline Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
The Efficacy and Safety of Low-dose Radiotherapy Combined With Sintilimab and Temozolomide in Recurrent Glioblastoma
Conditions: Recurrent Glioblastoma Interventions: Drug: Sintilimab; Radiation: Low-dose Radiotherapy Sponsors: Fifth Affiliated Hospital, Sun Yat-Sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM
Conditions: Glioblastoma Multiforme Interventions: Drug: Haloperidol Tablets; Drug: Temozolomide Sponsors: Southern Medical University, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials
Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
Conditions: Childhood Cancer; Childhood Solid Tumor; Childhood Brain Tumor; Recurrent Cancer; Refractory Cancer Interventions: Drug: Paxalisib, Irinotecan, Temozolomide; Drug: Pimasertib Sponsors: Australian& New Zealand Children ' s Haematology/Oncology Group; Children ' s Cancer Institute Australia (CCIA); The Hospital for Sick Children; Medical Research Future Fund; Kazia Therapeutics Limited; Day One Biopharmaceuticals, Inc.; C17 Council Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Tumors
Conditions: Digestive System Neuroendocrine Neoplasm; Lung Neuroendocrine Neoplasm; Malignant Solid Neoplasm; Pancreatic Neuroendocrine Neoplasm Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Biological: Incomplete Freund ' ' s Adjuvant; Procedure: Magnetic Resonance Imaging; Biological: Sargramostim; Biological: SVN53-67/M57-KLH Peptide Vaccine; Drug: Temozolomide Sponsors: Roswell Park Cancer Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma
Conditions: Glioblastoma Multiforme of Brain Interventions: Drug: Cisplatin Plus Temozolomide; Drug: Temozolomide Sponsors: Zhongnan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Conditions: Ganglioneuroblastoma; Neuroblastoma Interventions: Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Bone Scan; Drug: Carboplatin; Drug: Cisplatin; Procedure: Computed Tomography; Drug: Cyclophosphamide; Drug: Dexrazoxane; Biological: Dinutuximab; Drug: Doxorubicin; Drug: Etoposide; Procedure: FDG-Positron Emission Tomography and Computed Tomography Scan; Procedure: Hematopoietic Cell Transplantation; Drug: Irinotecan; Drug: Isotretinoin; Procedure: Leukapheresis; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Radiation: Radiation Therapy; O...
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials
Study of Olutasidenib and Temozolomide in HGG
Conditions: High Grade Glioma; Astrocytoma; Astrocytoma, Grade III; Astrocytoma, Grade IV; Diffuse Intrinsic Pontine Glioma; WHO Grade III Glioma; WHO Grade IV Glioma; Metastatic Brain Tumor; Diffuse Midline Glioma, H3 K27M-Mutant; Thalamus Tumor; Spinal Tumor; IDH1 Mutation; IDH1 R132; IDH1 R132C; IDH1 R132H; IDH1 R132S; IDH1 R132G; IDH1 R132L; Oligodendroglioma Interventions: Drug: Olutasidenib + TMZ Sponsors: Nationwide Children ' s Hospital; Rigel Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials
