Just Saying "No" to Adjuvant Temozolomide
Discovering that the medicine cabinet for my terminal disease was filled with fluff. (Source: Depth-First)
Source: Depth-First - August 31, 2023 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs

Temodar, MGMT Methylation, and the Endless Loop of Bad Glioblastoma Treatments
Understanding why half of patients will take a drug offering little to no benefit. (Source: Depth-First)
Source: Depth-First - August 6, 2023 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs

New Biomaterial Improves Brain Cancer Survival in Rats
Researchers from the University of Nottingham have developed a new biomaterial that delivers chemotherapies to treat brain cancer. Their work demonstrates that their biodegradable paste led to increased survival compared to controls, and that half of all rats in a study were clear of any cancer as confirmed by laboratory tests. This exciting development may one day improve treatment options for glioblastoma patients, as well as those with other cancers. Surgery is commonly performed to try to fight glioblastoma. Yet, one of the major challenges is that despite careful surgical removal of the tumor, some cancer cells may...
Source: Medgadget - July 24, 2019 Category: Medical Devices Authors: Siavash Parkhideh Tags: Materials Medicine Neurosurgery Oncology Source Type: blogs

Last Couple of Months in Oncology with Dr. Bishal Gyawali: March 2019
By BISHAL GYAWALI MD, PhD Hey, I’m back! Well, you might not have noticed that my blogs were missing for the last three months but anyways, its good to be back. I was having a little time off blogs and social media as I was transitioning in my career but now I am back. Sometimes, it is very difficult to manage time for things that you must do versus things you enjoy doing, especially when these two don’t intersect. For me, these last few months the things I had to do were all bureaucratic while I couldn’t find the time for things I enjoy doing like writing these blogs. But now that we are back, let’s rec...
Source: The Health Care Blog - March 26, 2019 Category: Consumer Health News Authors: Matthew Holt Tags: Medical Practice Physicians Bishal Gyawali Cancer drugs Clinical Trials Oncology Prostate Cancer RCTs Source Type: blogs

7 Things to Know About Glioblastoma
News recently shocked the nation that Sen. John McCain was diagnosed with an aggressive form of brain cancer called glioblastoma. Dr. Mark Mishra, a radiation oncologist at the University of Maryland Greenebaum Comprehensive Cancer Center and Maryland Proton Treatment Center who specializes in treating brain cancer, tells you 7 things to know about glioblastoma. How common is glioblastoma? Glioblastoma is the most common type of primary brain tumor that is diagnosed in adults.  There are estimated to be nearly 13,000 patients who will be diagnosed with a glioblastoma annually within the United States. Why is it so aggr...
Source: Life in a Medical Center - July 21, 2017 Category: Universities & Medical Training Authors: UMMC Tags: Cancer Source Type: blogs

Best Post of September 2012: DecisionDx-GBM: Should every glioblastoma patient be getting this test?
The next in our Best of the Month Series is from September 12, 2012. It's worth revisiting the question of whether or not genetic testing of brain tumors is appropriate in patients who are not on research studies: What does the neuropathology community think of DecisionDx-GBM? This is a product offered by Castle Biosciences, based in Phoenix, AZ. DecisionDx-GBM is a gene expression profile test developed at The University of Texas M. D. Anderson Cancer Center for the purpose of increasing the accuracy of the prognosis and predicted responsiveness of glioblastoma multiforme to first line radiation plus temozolomide. Th...
Source: neuropathology blog - April 9, 2013 Category: Pathologists Source Type: blogs