Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial
AbstractObjectivesTo assess the efficacy of local intranasal treatment with budesonide (nasal irrigation), in addition to olfactory rehabilitation, in the management of loss of smell in COVID-19 patients without signs of severity and with persistent hyposmia 30 days after the onset of symptoms.To search for an association between the presence of an obstruction on MRI and the severity of olfactory loss, at inclusion and after 30 days of treatment.Trial designTwo center, open-label, 2-arm (1:1 ratio) parallel group randomized controlled superiority trial.ParticipantsInclusion criteria- Patient over 18 years of age;- Patient ...
Source: Trials - July 19, 2020 Category: Research Source Type: clinical trials
