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Renin inhibition and the long-term renal function in patients with hypertensive emergency: a retrospective cohort study
CONCLUSIONS: DRI can successfully suppress PRA in patients with high-renin hypertensive emergency in both subacute and chronic phases. An efficient RAS blockade is associated with preserved renal function in these patients.PMID:37819695 | DOI:10.1093/ajh/hpad099 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - October 11, 2023 Category: Cardiology Authors: Masaki Ueno Wataru Fujii Wataru Ono Hiroshi Murata Yoshihide Fujigaki Shigeru Shibata Source Type: research

First-line diuretics versus other classes of antihypertensive drugs for hypertension
CONCLUSIONS: When used as first-line agents for the treatment of hypertension, thiazides and thiazide-like drugs likely do not change total mortality and likely decrease some morbidity outcomes such as cardiovascular events and withdrawals due to adverse effects, when compared to beta-blockers, calcium channel blockers, ACE inhibitors, and alpha-blockers.PMID:37439548 | PMC:PMC10339786 | DOI:10.1002/14651858.CD008161.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - July 13, 2023 Category: General Medicine Authors: Marcia Reinhart Lorri Puil Douglas M Salzwedel James M Wright Source Type: research

First-line diuretics versus other classes of antihypertensive drugs for hypertension
CONCLUSIONS: When used as first-line agents for the treatment of hypertension, thiazides and thiazide-like drugs likely do not change total mortality and likely decrease some morbidity outcomes such as cardiovascular events and withdrawals due to adverse effects, when compared to beta-blockers, calcium channel blockers, ACE inhibitors, and alpha-blockers.PMID:37439548 | DOI:10.1002/14651858.CD008161.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - July 13, 2023 Category: General Medicine Authors: Marcia Reinhart Lorri Puil Douglas M Salzwedel James M Wright Source Type: research

Impact of multimorbidity on mortality in heart failure with reduced ejection fraction: which comorbidities matter most? An analysis of PARADIGM ‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with coexistent PAD and stroke were at greatest individual risk whereas, from a population perspective, coexistent CKD and hypertension mattered most. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 25, 2023 Category: Cardiology Authors: Pooja Dewan, Jo ão Pedro Ferreira, Jawad H. Butt, Mark C. Petrie, William T. Abraham, Akshay S. Desai, Kenneth Dickstein, Lars Køber, Milton Packer, Jean L. Rouleau, Simon Stewart, Karl Swedberg, Michael R. Zile, Scott D. Solomon, Pardeep Tags: Research Article Source Type: research

Impact of multimorbidity on mortality in HFrEF: Which comorbidities matter most? – An analysis of PARADIGM‐HF and ATMOSPHERE
ConclusionsIn HF, the impact of multimorbidity differed at the individual-patient and population level, depending on the prevalence of and the risk related to each comorbidity, and the interaction between individual comorbidities. Patients with co-existent PAD and stroke were at greatest individual risk whereas, from a population perspective, co-existent CKD and hypertension mattered mostThis article is protected by copyright. All rights reserved. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 17, 2023 Category: Cardiology Authors: Pooja Dewan, Jo ão P Ferreira, Jawad H Butt, Mark C Petrie, William T Abraham, Akshay S. Desai, Kenneth Dickstein, Lars Køber, Milton Packer, Jean L Rouleau, Simon Stewart, Karl Swedberg, Michael R Zile, Scott D Solomon, Pardeep S Jhund, Tags: Research Article Source Type: research

Erratum notice for: "Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways" [Braz J Med Biol Res 2020;53(2): e8793]
Braz J Med Biol Res. 2023 Mar 17;56:e8793erratum. doi: 10.1590/1414-431X2023e8793erratum.ABSTRACT[This corrects the article doi: 10.1590/1414-431X20198793].PMID:36946843 | PMC:PMC10021487 | DOI:10.1590/1414-431X2023e8793erratum (Source: Brazilian Journal of Medical and Biological Research)
Source: Brazilian Journal of Medical and Biological Research - March 22, 2023 Category: Research Source Type: research

Erratum notice for: "Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways" [Braz J Med Biol Res 2020;53(2): e8793]
Braz J Med Biol Res. 2023 Mar 17;56:e8793erratum. doi: 10.1590/1414-431X2023e8793erratum.ABSTRACT[This corrects the article doi: 10.1590/1414-431X20198793].PMID:36946843 | PMC:PMC10021487 | DOI:10.1590/1414-431X2023e8793erratum (Source: Braz J Med Biol Res)
Source: Braz J Med Biol Res - March 22, 2023 Category: Research Source Type: research

Erratum notice for: "Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways" [Braz J Med Biol Res 2020;53(2): e8793]
Braz J Med Biol Res. 2023 Mar 17;56:e8793erratum. doi: 10.1590/1414-431X2023e8793erratum.ABSTRACT[This corrects the article doi: 10.1590/1414-431X20198793].PMID:36946843 | DOI:10.1590/1414-431X2023e8793erratum (Source: Braz J Med Biol Res)
Source: Braz J Med Biol Res - March 22, 2023 Category: Research Source Type: research

Erratum notice for: "Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways" [Braz J Med Biol Res 2020;53(2): e8793]
Braz J Med Biol Res. 2023 Mar 17;56:e8793erratum. doi: 10.1590/1414-431X2023e8793erratum.ABSTRACT[This corrects the article doi: 10.1590/1414-431X20198793].PMID:36946843 | DOI:10.1590/1414-431X2023e8793erratum (Source: Brazilian Journal of Medical and Biological Research)
Source: Brazilian Journal of Medical and Biological Research - March 22, 2023 Category: Research Source Type: research

Erratum notice for: "Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways" [Braz J Med Biol Res 2020;53(2): e8793]
Braz J Med Biol Res. 2023 Mar 17;56:e8793erratum. doi: 10.1590/1414-431X2023e8793erratum.ABSTRACT[This corrects the article doi: 10.1590/1414-431X20198793].PMID:36946843 | PMC:PMC10021487 | DOI:10.1590/1414-431X2023e8793erratum (Source: Braz J Med Biol Res)
Source: Braz J Med Biol Res - March 22, 2023 Category: Research Source Type: research