Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):670-676. doi: 10.18502/ijaai.v21i6.11527.ABSTRACTChronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ). We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immuno...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Shaghayegh Pezeshki Mir Hadi Jazayeri Bahram Chahardouli Nader Tajik Seyyed Massood Nabavi Mahdi Akbarzadeh Source Type: research